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Kumarraja Jayavarapu*, Dr. S. Parimalakrishnan, Dr. V. D Sundar Research Scholar, Department of Pharmacy, Annamalai University, Tamilnadu – 608002. A B S T R A C T A simple, sensitive, linear, precise and accurate RP – HPLC method for the estimation of Zaltoprofen was developed and validated. Zaltoprofen [(2RS)-2-(10-oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propionic acid] is a potent NSAID with powerful anti-inflammatory and analgesic effects ... Read More »
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Analytical Method Development and Validation for the Estimation of Erlotinib Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Gobala Krishnan P*, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy & Research centre, Nellore, Andhra Pradesh, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Erlotinib hydrochloride by using the HPLC method for Erlotinib hydrochloride as per ICH Guide lines. Shimadzu LC-2010 series ... Read More »
Development and validation of HPTLC method for analysis of ursolic acid from methanol extract of mimosoups elengi L
ABOUT AUTHOR Gayatri Ganu*1, Tushar A. Deshmukh2 1Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunuzunu, Rajasthan 2Department of Pharmacognosy, College of Pharmacy, Faizpur Abstract: Mimusops elengi L. (ME) is a small to large evergreen tree found all over the different parts of India. Bark of ME possesses cardio tonic, alexipharmic, stomachic, anthelmentic and astringent activity. The present investigation is an attempt to ... Read More »
Method development and validation for the simultaneous estimation of Nebivolol hydrochloride and S (-) Amlodipine besilate in tablet dosage form by RP – HPLC
About author Prabhakaran. V.*, Sekar. S., Baskar.E., Raghuprasath. V.R. Formulation Research and Development Department, The Madras Pharmaceuticals, Karapakkam, Chennai, Tamil Nadu, India. Email: rnd@madraspharma.com ABSTRACT High Performance Liquid Chromatography method was developed and validated in a simple, specific and precise manner for Nebivolol HCl and Amlodipine besilate in a combined solid dosage form. Nebivolol hydrochloride, a long acting, cardioselective β ... Read More »
A COMPARISION OF ANALYTICAL METHOD VALIDATION PROCEDURES
About author: Chinmaya Keshari Sahoo* Research Scholar,Dept. of Pharmaceutics, OUCT, Osmania University,A.P, India *e-mail: sahoo.chinmaya83@gmail.com INTRODUCTION : Analytical method validation is a regulatory requirement that refers to the evaluation and proving that the selected analytical method shall ensure reproducible and reliable results adequate for the intended purpose.The process of analytical method validation should demonstrate that the method is fit for ... Read More »
