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D. Sravika1, V.Anjeneyaulu2, Gampa Vijay Kumar3 1,2,3Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Medchal, Telangana, India. A B S T R A C T Atovaquone is a chemical compound that belongs to the class of naphthoquinones. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. The main objective of the present work was to ... Read More »
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Tag Archives: Solid dispersion
Formulation and Evaluation of Atorvastatin Calcium Solid Dispersions
Mahitha P1, Charitha M, Krishna sumanth K, Yasasvi P,Madhumitha L, Prudhvi Raj V*, Niranjan babu M Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupathi-517561 A.P, India A B S T R A C T Atorvastatin is useful in converting bad cholesterol to good cholesterol. As this bad cholesterol causes many diseases in human like increase in cholesterol levels in ... Read More »
Determining the Best Poly Ethylene Glycol as Solid Dispersion Carrier for Improvement of Solubility and Dissolution Rate of Ofloxacin
B. Faheem, Hindustan Abdul Ahad, Shameena S, Mohammed Asif M, Meena M, Abdul Riyaz S Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India A B S T R A C T The present investigation was to find out the best polyethylene glycol (PEG) as carrier to increase solubility of poorly soluble drug by taking Ofloxacin as model drug. PEG 1500, ... Read More »
Formulation and Evaluation of Immediate Fenofibrate Solid Dispersions
Dipak K.Borole*1, Hemant V.Deore1, Tanvirahmad J. Shaikh1, Jayshri A. Patil2, Harshal S. Bhandari 1 1DCS’S A.R.A College of Pharmacy, Nagaon, Dhule 2NES’S Gangamai College of Pharmacy, Nagaon, Dhule A B S T R A C T The aim of the present research work, Fenofibrate a BCS class II Anti hyperlipidemic drug belongs to fibrate class was formulated as solid dispersions ... Read More »
Formulation and Evaluation of Orally Disintegrating Tablets of Zolpidem Tartarate
S. Rajeshwari*, Soma Sekhar. G, Nazemoon.R, Razia Sultana, Hamshida .P. Khanam, M.BiBi. Fathima Safa college of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T Zolpidem tartarate is a super disintegrating tablet. It achieves rapid dissolution, absorption and further improving the bioavailability of drug. It is formulations by in-vitro method and to select the best formulation ... Read More »
Preparation and Evaluation of Solid Dispersions of Pioglitazone Using Skimmed Milk Powder as Carrier
A. Hemanth*1, H. Abdul Ahad2 1V. L .College of Pharmacy, Manik Prabhu Temple Road, Raichur-584103, India. 2Balaji College of Pharmacy, Rudrampeta Bypass, Anantapur-515001, India. A B S T R A C T Solubility is an important physicochemical factor affecting absorption of drug and its therapeutic effectiveness. Consequences of poor aqueous solubility would lead to failure in formulation development. The poor ... Read More »
Comparative study of different solvent extract of Olea dioica Roxb. Western Ghats, Karnataka, against selected plant and animal pathogenic bacteria
Ashwathanarayana.R*1, Raja Naika2 1Research student, Department of PG Studies and Research in Applied Botany, Jnanasahyadri, Kuvempu University, Shankaraghatta- 577451, Shimogga, district, Karnataka, India. 2Professor, Department of PG Studies and Research in Applied Botany, Jnanasahyadri, Kuvempu University, Shankaraghatta- 577451, Shimogga, district, Karnataka, India. A B S T R A C T Olea dioica Roxb. is a very important ethno medicinal evergreen tree ... Read More »
Development and Evaluation of Carvedilol Oral Disintegrating Tablet by Solid Dispersion Technique
Balachandrudu*, Somasekhar.G, Nazemoon.R, Raziya SMD. Department of Pharmaceutics, Safa College of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T Carvedilol is a poorly water soluble oral antihypertensive agent. An attempt has been made to develop fast dissolving the tablet of carvedilol by direct compression and solid dispersion technique the solid dispersion of carvedilol with peg-4000(1:4 ... Read More »
Development and Evaluation of Carvedilol Fast Disintegrating Tablet by using Superdisintegrants and Solid Dispersion Technique
Hyma.P*, Mahesh.M Scientific and Applied Research Center, Hyderabad, Telangana, India A B S T R A C T Carvedilol is a poorly water soluble oral antihypertensive agent. An attempt has been made to develop fast dissolving the tablet of carvedilol direct compression and solid dispersion technique the solid dispersion of carvedilol with peg-4000(1:4 molar ratio) by fusion extrusion method with ... Read More »
Ketoconazole Solubility Enhancement: Different Techniques and its Comparison
Author Details Ravi Prakash*, Shashi Shekhar Tripathi, Pravin Gupta, Rahul Dev, Anaagat Sir Madanlal Institute of Pharmacy Aalampur Hauz, Etawah-206001, U.P., India Abstract Four techniques namely melt sonocrystallization, solid dispersion, hydrotrophy and inclusion complex with cyclodextrin were used for the solubility enhancement. The order of the techniques for the solubility enhancement was found hydrotrophy>inclusion complex>solid dispersion>sonocrystallization method. Enhancement in the ... Read More »
