Nagamani*, J. Sreedevi, Y. Ankama Chowdary NRI College of Pharmacy, Krishna District, Andhra Pradesh, India A B S T R A C T Pulsatile dosage form taken at bed time with a programmed start of drug release in the early morning hours, can prevent a sharp increase in the incidence of heart attacks during the early morning hours. In the ... Read More »
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Tag Archives: Pulsatile Drug Delivery
Multi-component, Catalyst free Synthesis of α-Aminonitrile by Using of Glycerol as Recyclable and Green Solvent
Amir Hossein zamania*, Saeedeh shariatib, Hamid Reza Ghaienia aMalekAshtar University of Technology, Tehran, Iran, 1465943681 bAhvaz Jundishapur University of Medical Sciences. School of Pharmacy, Ahvaz, Iran, 1579461357 A B S T R A C T We describe the use of glycerol as an efficient, safe and recyclable solvent in the one-pot reaction of aldehydes, amines, and trimethyl silylcyanide to afford ... Read More »
Formulation and evaluation of pulsatile release tablets of Venlafaxine Hydrochloride
S. Masood Ahmed*, G. Somasekhar, R. Nazemoon, S. MD. Razia Sultana Department of Pharmaceutics, Safa College of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T Conventional tablet dosage form of venlafaxine HCl has a poor pharmacokinetic profile and shorter half life (5hrs) that necessitates 2-3 times daily dosing. Thus, this study attempts to design and ... Read More »
Formulation and evaluation of film coated pulsatile release tablets of Venlafaxine Hydrochloride
Hyma.P* Scientific and Applied Research Center, Hyderabad, Telangana A B S T R A C T Conventional dosage form of venlafaxine HCl has a poor pharmacokinetic profile and shorter half life (5hrs) that necessitates 2-3 times daily dosing. Thus, this study attempts to design and evaluate a chronomodulated pulsatile drug delivery system of venlafaxine by rupturable coating method. The core ... Read More »