Pharma Research Library | Pharma Info Index Research | Innovation | Opportunities |

El Houssine Mabrouk1 1Laboratory of Organic Chemistry, Faculty of Sciences DharElMehraz, University Sidi Mohamed Ben Abdellah, Fez, B.P.:1796-Fès Atlas, Morocco ABSTRACT The title compound, N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide2, was synthesized in high yield, via N-alkylation reaction of methyl 2-azido-2-benzamidoacetate or methyl 2-bromo-2-benzamidoacetate with o-phenylenediaminein acetone, with the presence of diisopropylethylamine(DIEPA) as a base. The structure of the prepared compound was characterized by 1H, ... Read More »

Thriveni*, T. Sekhar, M. Hari Krishna, K. Murali Department of Chemistry, Vikrama Simhapuri University, Nellore-524001, A.P, India. A B S T R A C T A general, mild and efficient protocol for the synthesis of 1,5- benzodiazepine derivatives is achieved for first time using Silver triflate as a catalyst by a one pot, three-component condensation of ethylacetoacetate, aldehyde and o-Phenylenediamine. ... Read More »

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, India E-mail : dhanipharmachem@gmail.com Abstract: Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5,6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12.The benzimidazoles are also known as benziminazolones or benzoglyoxalines.The new benzimidazole derivative i.e, 2-mercapto benzimidazole was synthesized.The melting point ... Read More »

About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5, 6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12. Diversity ... Read More »