Akanksha Jethmal*1, Amit K Agrawal2, Archana Tiwari2 1Department of Pharmaceutics, Vedica College of B.Pharmacy, Bhopal, M.P, India 2Department of Pharmaceutics, Patel College of Pharmacy, Bhopal, M.P, India A B S T R A C T The aim of present study was to prepare proniosomal gel for the topical drug delivery. Ketoconazole was used as proniosomal gel with sorbitol by using ... Read More »
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Ketoconazole Solubility Enhancement: Different Techniques and its Comparison
Author Details Ravi Prakash*, Shashi Shekhar Tripathi, Pravin Gupta, Rahul Dev, Anaagat Sir Madanlal Institute of Pharmacy Aalampur Hauz, Etawah-206001, U.P., India Abstract Four techniques namely melt sonocrystallization, solid dispersion, hydrotrophy and inclusion complex with cyclodextrin were used for the solubility enhancement. The order of the techniques for the solubility enhancement was found hydrotrophy>inclusion complex>solid dispersion>sonocrystallization method. Enhancement in the ... Read More »