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Tag Archives: ICH guidelines

Preparation, Standardization and In Vitro anti-arthritic evaluation of poly herbal formulation

Gollapalli Divya Mounika*, Y. Prapurna Chandra, C. Madhavi Latha Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District – 524 346 A b s t r a c t The present study is to formulate an ayurvedic capsule for treatment of arthritis. The formulated capsules are evaluated as per WHO guidelines and also performed pharmacological ... Read More »

RP-HPLC Method Development and Validation for the Simultaneous Estimation of Oxycodone and Naltrexone in Pharmaceutical Dosage Form

Ch. Sravani Phanithavya*, K.N. Maneesha, M. Sreenivasulu, Y. Prapurna Chandra Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District–524 346 Abstract The aim of this study is to develop and validate a new RP-HPLC method for the Simultaneous Estimation of Oxycodone and Naltrexone in Pharmaceutical Dosage Form. The estimation of Oxycodone and Naltrexone was ... Read More »

Develop a new, simple, fast, rapid, accurate, efficient and Reproducible RP-UPLC Method for the Simultaneous analysis of Metformin and Saxagliptin

A. Srikanth*, G. Srikanth1, Shaik afroz begum2, Machiraju Sai Kalyan3 *Associate Professor, Dept. of Pharmaceutical Analysis Vasavi institute of pharmaceutical sciences, Kadapa. 1Assistant Professor, Dept. of Pharmaceutics, Vasavi institute of pharmaceutical sciences, Kadapa. 2Assistant Professor, Dept of Pharmaceutical Chemistry, Vasavi institute of pharmaceutical sciences, Kadapa. 3Student, Department of Pharmaceutical Analysis, Vasavi institute of pharmaceutical sciences, Kadapa. Abstract Introduction: Metformin decreases ... Read More »

Development and Evaluation of Multi-Layer Controlled Release Tablet of Pentoxifylline

K. Sunil Kumar*1, M. Lokesh2 1Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A b s t r a c t In the present study an attempt was made to prepare Pentoxifylline Extended release tablet for the treatment of ... Read More »

Development and Validation of UV-VIS Spectrophotometer Method for Estimation of Flavonoid in Tagetes Erecta

V. Amaravathi*, M. Murali, Sk. Nagoor Shareef, Thatiparthi Harshitha, Thummala Likhitha Priya Jagans College of Pharmacy, SPSR Nellore, Andhra Pradesh, India A b s t r a c t For the determination of Quercetin in the Tagetes Erecta extract, a rapid, clear, selective and accurate UV-Visible Spectrophotometric method has been developed. The detection was carried out using ethyl acetate as ... Read More »

Method Development and Validation for the Simultaneous estimation of Velpatasvir and Sofosbuvir in tablet dosage form by using RP–HPLC

M. Anusha*, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kunrool, Andhra Pradesh, India A B S T R A C T The present research work mainly focused on method development and validation for the simultaneous estimation of velpatasvir and sofosbuvir in tablet dosage form by using RP-HPLC. Chromatographic separation was carried on YMC C18 column (4.6*150mm, ... Read More »

Development of New RP-HPLC method for the estimation of Glycopyrrolate and Formoterol fumarate in the tablet dosage form

Damam Vidya*, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kunrool, Andhra Pradesh, India A B S T R A C T The present research work mainly focused on method development and validation for the simultaneous estimation of Glycopyrrolate and Formeterol fumarate in tablet dosage form by using RP-HPLC. Chromatographic separation was achieved on Xterrra C18 column ... Read More »

Analytical Method Development and Vaidation for Ombitasvir and Paritaprevir in Combined Dosage Form by RP-HPLC

K.Nithiyananthan1*, K.V.S.Prasadarao2 1Research Scholar,  Acharya Nagarjuna University, Guntur, Andhra Pradesh 522510. 2Principal, Rahul Institute  of Pharmaceutical Sciences And Research, Chirala, Andhra Pradesh 523157 A B S T R A C T Ombitasvir and Paritaprevir by using Thermosil C18 column (4.0×125mm) 5µ, flow rate was 1ml/min, mobile phase ratio was (70:30 v/v) methanol: Sodium acetate buffer pH 3 (pH was adjusted ... Read More »

Review on Analytical Method Validation Procedures

k. Surendra*, SK. Karishma, G. Obulesu, M. Naveena Rao’s College of Pharmacy, Chemudugunta, Venkatachalam, Nellore, Andhra Pradesh-524320 A B S T R A C T Pharmaceutical analysis plays a very prominent role in quality assurance as well as quality control of bulk drugs and pharmaceutical formulations, of which analytical method development & validation is the basic activity. Analytical techniques are ... Read More »

A Novel RP-HPLC Method Development and Validation for the Estimation of Pyrimethamine in Bulk and its Pharmaceutical Formulation

U. Srinivasulu*1, N. Devanna2, A. Sandhya 3, B. Siva Sai Kiran3, S. Muneer3 1Associate Professor of Chemistry, SBSYM Degree College, Kurnool-518004, A.P., India 2Professor and Director, Department of Chemistry, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India. 3Department of Pharmaceutical Sciences, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India A B S T R A C T A simple, ... Read More »

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