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Shaik Salmasultana*, P. Sukumari, SK. Shafi, D. Maheswari, P. Ramsai, K. Sasikumar, A. Sravani Department of Pharmacology, Jagan’s Collegeofpharmacy, Gangalakandriga, Nellore A B S T R A C T The antidepressant activity of eugenol excluded clove extract was investigated using two different models of stress induced depression (forced swim test and Tail suspension method). Animals were divided into different groups each ... Read More »
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In-Silico Structure-Activity Relationship and Molecular Docking Study of Levofloxacin and its Mono substitted Analogues against the Escherichia coli DNA Gyrase
O.A Durojaye*, U. I Njoku, S. Cosmas, E. N Akpan, M. M Ganyam University of Nigeria, Nsukka. A B S T R A C T Background: Escherichia coli is one of the most frequent causes of many common bacterial infections, including cholecystitis, bacteremia, cholangitis, urinary tract infection (UTI), traveler’s diarrhea, and other clinical infections such as neonatal meningitis and pneumonia. ... Read More »
Method Development and Validation of Sofosbuvir and Ledipasvir in API & Its Pharmaceutical dosage forms by RP-HPLC
Shinnde Sandeep* Department of Pharmaceutical Analysis & Quality Assurance ,SSJ College of Pharmacy,Vattinagulapally, Gandipet, Hyderabad – 500075, Telangana State A B S T R A C T Ledipasvir is indicated in patients with hepatitis C virus (HCV) genotype 1 for treatment of chronic hepatitis as a combination therapy, which includes peg interferonalfa and ribavirin. Ledipasvir is a protease inhibitor for ... Read More »
Evaluation of Prescription Pattern of Drugs for Rheumatoid Arthritis Patient
Sravani K*, B. Kumar Department of Pharmacy Practice, Ratnam institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore district-524 346 A B S T R A C T Rheumatoid Arthritis has emerged as important clinical and public health problem Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints. Autoimmune diseases are illnesses that occur when the ... Read More »
Synthesis and antimicrobial activity of Schiff base of quinolene-2-ones
Dr. Alka Pradhan and Sanjay Kumar Vishwakarma* Professor, Department of Chemistry, S. N. Govt. G.P.G. College Bhopal. *Research Scholar, Department of Chemistry, S .N. Govt. G.P.G. College Bhopal. A B S T R A C T In the present study, we synthesized Schiff bases of quinolene-2-one and their antibacterial activity was evaluated by wells diffusion method. Schiff bases of quinolene-2-one ... Read More »
Development and Validation of new UV-Visible Spectrophotometric Method for the Estimation of Losartan in Tablet Dosage Form
*Suruchi Samparna Acharya, R. Maneesha, L. Manikanta, M. Ajay Kumar, P. Gowthami, B. Hareesh Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukuru (M), Nellore, Andhra Pradesh, India. A B S T R A C T A simple, Accurate, precise method was developed for the estimation of Losartan in Tablet dosage form. Solutions of Losartan were prepared in solvent like methanol ... Read More »
RP-HPLC Method Development and Validation for Simultaneous Estimation of Bupropion and Naltrexone in Bulk and Pharmaceutical Dosage Forms
Sanju Srinivas and V. Nirmala* Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana *Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T Thus the proposed stability indicating RP-HPLC technique for the synchronic determination of Naltraxone and Bupropione in bulk and pharmaceutical dosage form was accurate, precise, linear, reliable, simple, economic ... Read More »
Simultaneous Estimation of Amlodipine and Atenolol by Using Reverse Phase High Performance Liquid Chromatography in Bulk and Marketed Formulation
Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India. Abstract A simple precise and accurate reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for the simultaneous estimation of Amlodipine and Atenolol. Chromatographic separation was achieved on Altima C18 column (4.6×150mm, 5µ) using the mobile phase consisting of Methanol: TEA ... Read More »
Evaluation of Antidepressant Activity of Mimosa Pudica in Experimental Mice
Gampa Vijaya Kumar*1, Dr. Y. Sridhar2, A. Mounika3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor, KGR Institute of Technology and Management, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T Depression is the most common ... Read More »
Formulation and In-vitro Evaluation of Ergotamine Tablets for Buccoadhesive Drug Delivery System
Gampa Vijaya Kumar1, Dr. G.S. Valluri2, Thota Karunakar3 1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T Ergotamine was formulated as ... Read More »
