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J. Bhaskar1*, T. Ramchandar2, V.L. Narasaiah3 1Dept. of Pharmaceutics, Princeton Institute of Pharmaceutical Sciences, Hyderabad, Telangana, India. 2Dept. of Pharmaceutics , Mother Teresa college of Pharmacy, Ghatkesar, Hyderabad, Telangana India. 3Dept. of Pharmaceutics, Dr Samuel George Institute of Pharmaceutical Sciences, Markapur, A.P, India. A B S T R A C T The purpose of this research was to study bioadhesive ... Read More »
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Formulation and Evaluation of Ondansetron Hydrochloride Bilalyered Buccal Tablets: I an In Vitro and Ex vivo
J. Bhaskar1*, T. Ramchandar2, V.L. Narasaiah3 1Dept. of Pharmaceutics, Princeton Institute of Pharmaceutical Sciences, Hyderabad, Telangana, India. 2Dept. of Pharmaceutics , Mother Teresa college of Pharmacy, Ghatkesar, Hyderabad, Telangana India. 3Dept. of Pharmaceutics, Dr Samuel George Institute of Pharmaceutical Sciences, Markapur, Prakasam, A.P, India. A B S T R A C T The aim of the present study was to ... Read More »
RP-HPLC Method Development and Validaton for the Simultaneous Estimation of L-Methyl Folate and EscitalopramIn Bulk and Its Pharmaceutical Dosage Form
Guvvala Triveni, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, Andhra Pradesh, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the L-methyl folate and Escitalopram in bulk and its pharmaceutical dosage form.Chromatographic separation was carried on Denali C18(150 x 4.6 mm, 5µ) column . Mobile phase consist of Phosphate buffer and ... Read More »
Stability Indicating RP-HPLC Method for Simultaneous Estimation of Lumacaftor and Ivacaftor in Bulk and Pharmaceutical Dosage Forms
Pasala Sandhya Mounika, Rameeja Pattan* Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore ABSTRACT A simple, fast, accurate, precise, reproducible Stability indicating Reverse phase High performance liquid chromatography (RP-HPLC) method was developed and validated for the determination of Lumacaftor and Ivacaftor in Bulk and pharmaceutical dosage form. Chromatographic separation was done by using Agilent Eclipse XDB-C8 column ... Read More »
Stability Indicating RP-HPLC Method for Simultaneous Estimation of Sofosbuvir and Velpatasvir in Bulk and Pharmaceutical Dosage Form
V. Hari Baskar, Ramesh Dhani*, P. Priyanka, M. Suchitra Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore. ABSTRACT A simple, precise, accurate rp-hplc method has been developed and validated for the sofosbuvir and velpatasvir in bulk and pharmaceutical dosage form. This method was carried out by using Inertsil ODS-3(4.6 x 150mm, 5mm). Mobile phase containing phosphate buffer (ph4.8): ... Read More »
Identification of Candidate Inhibitory Ligands from Allium cepa and Molecular Docking Against Trypanosma brucei Phosphoglycerate Kinase; The In-Silico Structure-Activity Relationship
S. Cosmas, O.A Durojaye*, R. O Asomadu, I. N Amorha, O. I Diyoke, G. A Osegbo Department of Biochemistry, University of Nigeria, Nsukka A B S T R A C T Trypanosoma brucei is a unicellular parasite causing African sleeping sickness in cattle and humans. Infection occurs when a vector tsetse fly bites a mammalian host. The fly injects the ... Read More »
A Review of Anticoagulant Activity of a Fucoidan from Undaria Pinnatifida Sporophy ll
Chirumanu Ramadevi*, Kongi Kavya Sudha, Ballavolu Sandeep Swathi College of Pharmacy, Venkatachalam, Nellore Abstract Undaria pinnatifida is brown sea weed. Fucoidan is a group of marine sulfated polysaccharides of the cell-wall matrix of brown algae, containing large proportion of L-fucose and sulfate, together with minor amounts of other sugar like xylose, galactose, glucose, mannose, uronic acid, and rhamnose. Fucoidan medically ... Read More »
Phytochemical constituent, percentage yield and phenolic content estimation of different solvent system of Carica papaya leave.
SHENENI Victor Duniya1*, MAMUDU Collins Ojonugwa1, ADAMU Danjuma Adamu1, OKPE John Mathias1, SHAIBU Isaac Eleojo1, USMAN Oman Salifu2 1Department of Biochemistry, Kogi State University, Ayingba, Nigeria. 2Department of Chemistry, Kogi State University, Ayingba Kogi, Nigeria ABSTRACT Carica papaya is an important medicinal plant used in the management of different disease conditions. Phytochemical screening was carried out using different chemical test, ... Read More »
Method Development and Validation of Acetazolamide Single Drug Molecule by Using UV Double Beam Spectrophotometer
Rameeja Pattan*, M. Charitha, M. Hemalatha, C. Lalitha, P. Pravallika, M. Vyshnavi, V. Sneha Priya Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore-524 346, Andhra Pradesh ABSTRACT This UV-spectrophotometric technique is quite simple, accurate, precise, reproducible, and sensitive. The UV method has been developed for quantification of Acetazolamide in tablet formulation. The validation procedure confirms that this is an appropriate ... Read More »
Synthesis of Some Novel Benzimidazole Derivatives & Evaluation of Their Antibacterial Activity
Jayakumar.A*, Ramesh Dhani, Sindhu.P, Ayesha.K, Keerthi. V, Rajeswari.P, Sukanya.P, Vijayadurga.P, Department of Pharmaceutical Chemistry, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District-524 346 ABSTRACT Benzimidazoles are heterocyclic compounds in which benzene is fused with five membered ring containing two hetero atoms. Both hetero atoms are nitrogen (N), which are present at non-adjacent position. It has broad spectrum ... Read More »
