Wednesday , 17 July 2024

Method Development and Validation for the Assay of Nebivolol Tablets by using RP-HPLC

1N. Kalpana Devi*, 2Pradeep Reddy, 3D.S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3 Vikas Institite of Pharmaceutical Sciences, Rajahmundary ABSTRACT A simple, precise, and accurate gradient reversed-phase (RP)  high-performance liquid chromatographic (HPLC) assay method was developed and validated for determination of nebivolol in tablet dosage forms. gradient RP-HPLC separation was achieved on a Phenomenex, kinetex ... Read More »

Synthesis, Characterization and Biological Activities of Thiadiazole Derivative

G. Nagaraju*1, Dr. Sunil Kumar bainda*2 1Research Scholar, Department of Pharmaceutical Chemistry, OPJS University, Churu, Rajasthan 2Dr. Sunil Kumar, OPJS University, churu, Rajasthan A B S T R A C T Isatin (indole-2, 3-dione) is an endogenous compound, widely distributed in mammalian tissues and body fluids. Isatin chemically known as 1H-indole-2, 3-Dione. It   is a unique molecule possessing both amide ... Read More »

Formulation and Evaluation of Famotidine Floating Micro Beads

A. Sai Kiran, K. Prasanna Kumar, K. Sravani, V. Agni, A. Lakshmi Prasanna, T. Kalyani, P. Venkata Madhu Sudhan Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukuru (M), Nellore, Andhra Pradesh, India. ABSTRACT The main objective of the present study was to prepare and evaluate Floating Micro Beads of Famotidine from the prepared beads by iontotropic gelation method. The FT-IR confirmed ... Read More »

Development and Validation of a New Method for the Simultaneous Estimation of Metformin and Linagliptin in Bulk and Dosage form by using UV–Spectrophotometry

M. Mallikarjuna*, C. Guru Sudhakar, K. Siva Shankar, SK. Abid, P. Rameeja Ratnam Institute of Pharmacy, Pidathapolur, Nellore, AP, India ABSTRACT A Simple, Determined, and precise method to develop a new quantitative simultaneous identification of metformin hydrochloride and Linagliptin in combined pharmaceutical dosage forms. This method was based on the based on the UV spectrophotometric method for the simultaneous estimation of ... Read More »

Interplay Between Brain Stress Markers and Cognito-Motor Behaviour and Coordination in Starvation- Induced Stress in Rats

Olorunfemi O.J., Bohr E.L.S., Okosiemiama S.C., Okopido I.S, Okpe E. Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Choba, Port Harcourt, Nigeria. ABSTRACT The impact of stress (which is a common daily occurrence) is strongly influenced by the type and duration of the stressor. The study was done to ascertain the ... Read More »

Evaluation of Antiurolithiatic Activity of Rhynchosia Minima by using Ethylene Glycol-Induced Urolithiasis in Rats

S. Parveen*, B. Mayuri Department of Pharmacology, Santhiram College of Pharmacy, Nandyal, A.P Abstract The objective is to study the antiurolithiactic activity of “Rhynchosia minima” by using ethylene glycol induced urolithiasis in male albino rats of wistarstrain.The urolithiasis was induced in rats by oral feeding of ethylene glycolated water (0.75%v/v) for 28 days ethanolic extract of “Rhynchosia minima” (200mg/kg,400mg/kg) was ... Read More »

A Review on Serotonin Syndrome

Murugala Sravani*, Chitturi Santhiswaroopa, Jarugula Nagaraja M A M College of Pharmacy, Kesanupalli, Narasaraopet, Guntur, Andhra Pradesh-522601 Abstract Serotonin syndrome is a potentially dangerous syndrome that is accumulation of serotonin levels will be observed by the use of serotonergic drugs and hyperactivity of both the peripheral and central postsynaptic 5HT-1A and, most probably, 5HT-2A receptors.  A combination of mental status ... Read More »

Chromosomal Aberrations As an Evidence of Genetic Damage in the Offspring of Methyl Isocyante Exposed Population of Bhopal

Ravi Sukumaran1, Tahir Mohiuddin Malla2, Rekha Khandia3, N. Ganesh1* 1Department of Research, Jawaharlal Nehru Cancer Hospital & Research Centre, Idgah Hills, Bhopal M.P 2Cancer Diagnostic and Research Centre, Sher-i-Kashmir Institute of Medical Sciences, Srinagar (J&K) 3Department of Biochemistry & Genetics, Barkatullah University, Bhopal (M.P.) A B S T R A C T Introduction: Bhopal gas tragedy was one of the ... Read More »

Development and Validation of Micellar Electrokinetic Chromatographic Assay Method for Simultaneous Estimation of Antihypertensive Drugs in Pharmaceutical Formulations

A. Ramyasree1*, Dr. R. Sekar2 1NRI college of Pharmacy, Vijayawada, Andhra Pradesh 2Indian Institute of Chemical Technology (IICT), Hyderabad, Telangana A B S T R A C T A micellar electrokinetic capillary chromatographic (MEKC) method has been developed for the simultaneous determination of anti-hypertensive drugs amlodipine (AM) and lisinopril (LS) in pharmaceutical formulations. Analysis was performed in a 75 µm ... Read More »

Lassa Fever

G. Sadhana*, Nilsha Anil, R. Ramprasad, N. Venkateshan and Amutha Iswaryadevi Department of Pharmacy, Arulmigu Kalasalingam College of Pharmacy,Krishnankoil-626126 A B S T R A C T To Focus on LASSA VIRUS about it’s prevalence and it’s treatment LASSA fever is an acute Viral Haemorrhagic illness of 2-21 days duration that Occurs in West Africa. Though first described in 1950’s ... Read More »

Scroll To Top