Sunday , 30 June 2024

New carboxylic α,α-diamino acids: 2-benzamido-2-(benzylamino) acetic acid and 2-benzamido-2-(N,N-dibenzylamino) acetic acid

El Houssine Mabrouk* Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco A B S T R A C T New α,α-diamino acids derivatives, as  2-benzamido-2-(benzylamino) acetic acid and 2-benzamido-2-(N,N-dibenzylamino) acetic acid were synthesized in high yield through alkaline hydrolysis reaction of corre威而鋼 sponding N-benzoylated methyl α,α-diamino esters. The structure ... Read More »

Synthesis of the new carboxylic α,α-diamino acids: 2-benzamido-2-(N-benzyl N-methylamino) acetic acid and 2-benzamido-2-(N-benzyl N-ethylamino) acetic acid

El Houssine Mabrouk* Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco A B S T R A C T We reported here the synthesis of new α,α-diamino acids derivatives, as  2-benzamido-2-(N-benzyl N-methylamino) acetic acid and 2-benzamido-2-(N-benzyl N-ethylamino) acetic acid through alkaline hydrolysis reaction of corresponding N-benzoylated methyl α,α-diamino esters. ... Read More »

Prevalence and Antimicrobial Susceptibility of Asymptomatic Bacteriuria among the Pregnant Women at Tertiary Care Teaching Hospital, Tirupati, Andhrapradesh, India – A Retrospective Study

Dr. Chandrakala Penagadam1*, Dr. B. Kailasanatha reddy2, Dr. MadhusudanaPulaganti3 1Assistant Professor, Dept of Microbiology, S.V. Medical College, Tirupati, India-517507 2Professor & HOD, Dept of Microbiology, S.V. Medical College, Tirupati, India-517507 3BIF, Dept of Biochemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India-515003 Abstract Aim: This retrospective study aims to demonstrate the prevalence of asymptomatic bacteriuria by aerobic bacterial uropathogens among the ... Read More »

Bacteriologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Skin Burns – A Retrospective Study at Tertiary care Teaching Hospital, Tirupati, Andhrapradesh, India.

Dr. Chandrakala Penagadam1*, Dr. B. Kailasanathareddy2, Dr. B. Subbulu3, Madhusudana Pulaganti 1Assistant Professor, Dept of Microbiology, S.V. Medical College, Tirupati, India-517507 2Professor & HOD, Dept of Microbiology, S.V. Medical College, Tirupati, India-517507 3Assistant Professor, Dept of Microbiology, S.V. Medical College, Tirupati, India517507 4BIF, Dept of Biochemistry, Sri Krishnadevaraya University-515003. Abstract Aim: To demonstrate the prevalence of isolated aerobic microorganisms in ... Read More »

Design and Characterization of Hydrogel based Mesalamine Microbeads for Colon Targeted Drug Delivery System

Tadakapally Ramchandar1*, Jimidi Bhaskar2, Kanakam vijaya Bhaskar3, V.L. Narasaiah4 1Department of Pharmaceutics, Mother Teresa college of Pharmacy, Ghatkesar, Hyderabad, Telangana. 2Department of Pharmaceutics, Avanthi Institute of Pharmaceutical Sciences, Gunthapally, Near Ramoji Film city, Hyderabad, Telangana, India. 3Department of Pharmacognosy, Sahasra Institute of Pharmaceutical Sciences, Warangal, Telangana. 4Dept. of Pharmaceutics, Dr Samuel George Institute of Pharmaceutical Sciences, Markapur, A.P, India. A ... Read More »

Evaluation of Hepatoprotective Activity of Methanolic Leaf Extract of Evolvulus nummularius Linn.

G. Sindhu*, V. Jayashankar Reddy, T. Usha Kiran Reddy S V U College of Pharmaceutical Sciences, S.V University, Tirupati–517502. A B S T R A C T The present study was aimed to explore the hepatoprotecive activity in aqueous whole plant extract of EN on rats. Acute toxicity studies were conducted in Male Wistar rats by using OECD guidelines No.423. ... Read More »

A Brief Study on Steviarebaudiana–A Review

T. Usha Kiran Reddy*, R. Gouri, G. Sindhu, R. Harsha, K. Thyagaraju S V U College of Pharmaceutical Sciences, S.V University, Tirupati–517502. A B S T R A C T Stevia rebaudiana belongs to Asteraceae family and is popularly known as candy leaf. Stevia rebaudiana Bertoni is a sweet tasting medicinal herb; and has been known to contain calorie-free natural ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Darunavir and Cobicistat by RP- HPLC Method

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, T. Naga Sirisha Devi3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, ... Read More »

Novel RP-HPLC Method Development and Validation of Dasatinib and Lenvatinib in Bulk and Pharmaceutical Dosage Forms

Dr. K. Nageswara Rao1*, 2Raghava Doonaboyina, Hope Evangeline3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A ... Read More »

Prospective Assessment of Drug Utilization Practice of Anti Epileptic Medications in the Management of Epilepsy Associated Comorbidites in a Tertiary Care Hospital

C.L. Sindhura*, B. Kumar, D. Sujana, M. Bhargavi Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidathapolur  (V&P), Muthukur (M), SPSR Nellore (Dist) 524346, Andhra Pradesh, India. A B S T R A C T It is a central nervous system condition where the brain experiences recurrent seizures. A seizure is the outward manifestation of the synchronous and excessive excitement ... Read More »

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