Thursday , 11 July 2024

Simultaneous estimation and validation of Lumacaftor and Ivacaftor in the tablet dosage form using RP-HPLC method

S. Kantha Lakshmi*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim present research work to development and validation of RP-HPLC method for the simultaneous estimation of Lumacaftor and Ivacaftor. Chromatographic separation was evaluated by Phenomenex C18 column (250 X 4.6 mm, ... Read More »

Development of New simultaneous RP-HPLC method for the estimation of Pentazocine HCl and Naloxone HCl in tablet dosage form

M. Sowbhagya Lakshmi*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim of present research work made to develop and validate RP-HPLC method for the simultaneous estimation of Pentazocaine and Naloxone in bulk and combined dosage form. The optimized mobile phase was ... Read More »

Development of new simultaneous RP-HPLC method for the estimation of Glecapravir and Pibrentasvir in tablet dosage form

M. Lakshmi Prasanna*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim present research work to development and validation of RP-HPLC method for the simultaneous estimation of Glecapravir and Piberentasvir. Chromatographic separation was evaluated by Xterra C18 column (250 X 4.6 mm, ... Read More »

Analytical Method Development and Validation for Tranexamic Acid and Ethamsylate in Combine Dosage Form by RP-HPLC

1V. Bhavani*, 2Priyanka K Department of Pharmaceutical Analysis, Smt. Sarojini Ramulamma college of Pharmacy, Sheshadri Nagar, Mahabubnagar, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Tranexamic acid and Ethamsylate   by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Tranexamic acid and Ethamsylate by using Inertsil ... Read More »

Evaluation of Hepatoprotective activity of Delonix Elata against Carbontetra chloride, Paracetamol and ethanol induced Hepatotoxicity in rats

P. Sripal Reddy*¹, M. Raghavendra¹, M. Venkata Kirankumar¹, K. Abbulu² ¹Dept. of Pharmacology, CMR College of Pharmacy, Kandlakoya, Medchal Road, Hyderabad-501401, Telangana, India. ¹Associate Professor, Department of Pharmacology, CMR College of Pharmacy, Kandlakoya, Medchal Road, Hyderabad-501401, Telangana, India. ¹HOD, Department of Pharmacology, CMR College of Pharmacy, Kandlakoya, Medchal Road, Hyderabad-501401, Telangana, India. ²Principal, Department of Pharmaceutics, CMR College of Pharmacy, ... Read More »

Dermal Wound Healing Processes of Terminalia Arjuna Extract Impregnated Collagen Dermal Scaffolds

D. Krishna Priyanka*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India-518218 A B S T R A C T The aim of this work is to design and fabricate  a collagen based dermal scaffold containing Terminalia Arjuna extract for the improvement in process of wound healing. For this purpose Collagen was ... Read More »

Formulation and Evaluation of Microspheres of Aceclofenac

Murugan Mounika1, Nallapu Prathyusha Evangelin2, Nomula Chaitanya3, B. Prabhakar Reddy*4 1,2,3Vignan Institute of Pharmaceutical Sciences, Vignan Hills, Deshmukhi, Yadadri, Bhongir, Telangana, India. 4Associate Professor, Department of Pharmaceutics, Vignan Institute of Pharmaceutical Sciences, Vignan Hills, Deshmukhi, Yadadri, Bhongir, Telangana, India. A B S T R A C T In the present work, Aceclofenac microspheres using HPMC K 4 M., Eudragit L100, Eudragit ... Read More »

Solubility Enhancement of Nifedipine Using Liquisolid Compact Technique

S. Shehanaz Begum*, C. S. Parameswari, B.V. Ramana, G. Nagarajan Dr.K.V.Subba Reddy Institute of Pharmacy, Kunrool, Andhra Pradesh, India A B S T R A C T The objective of the present investigation was to formulate and evaluate conventional tablets of Nefidipine by solubility enhancement liquisolid technique. Liquisolid technique is a new and promising method that can change the dissolution ... Read More »

Treatment of Asthma by Chronotherapeutic Drug Delivery System using Salbutamol Sulphate

D. Manasa*, C. S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kunrool, Andhra Pradesh, India A B S T R A C T The objective of the present investigation was to formulate and evaluate Salbutamol sulphate by chronotherapeutic drug delivery system. In chronopharmacotherapy (timed drug therapy) drug administration is synchronized with biological rhythms to produce ... Read More »

Method Development and Validation of Suvorexant in Tablet Formulation by using UV Double Beam Spectrophotometer

Moguloori. Sai Sowmya1, Molugu. Prudhvi2, Moola. Manisha3, S. Rajasree4, Dr. M. Srinivasa Murthy5 , P. Dhanunjaiah6 1,2,3Vignan Institute of Pharmaceutical Sciences, Deshmukhi, India. 4Assistant Professor and Dept. of Pharmaceutical Analysis, Vignan Institute of Pharmaceutical Sciences, Deshmukhi, India. 5Professor and Dept. of Pharmaceutical Chemistry, Vignan Institute of Pharmaceutical Sciences, Deshmukhi, India. 6Assistant Professor and Dept. of Pharmaceutical Analysis & Quality Assurance, Vignan ... Read More »

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