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JagadeswaraRao K1,2, Murali Mohan SV 2and *Rama Rao Malla1 1Department of Biochemistry, Cancer Biology Lab, GIS, GITAM University, Visakhapatnam, India 2Analytical Research and development Department, Shilpa Medicwere Limited, India 3Department of Chemistry, GIS, GITAM University, Visakhapatnam, India A B S T R A C T The pharmaceutical formulation manufacturing process use some of polymers, which contains traces of inorganic elements ... Read More »
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Evaluation of Adverse Drug Reactions in General Medicine Department of a Tertiary Care Hospital: A Cross-sectional study
Kiran Kumar Chemudugunta*1, Dr. Habib Habibuddin M2 1Research Scholar, Rayalaseema University, Kurnool, Andhra Pradesh, India 2Principal, Shadan College of Pharmacy, Hyderabad, Telangana, India A B S T R A C T Background: In hospital settings, Adverse Drug Reactions (ADRs) are the major cause for the increased length of hospital stay, cost, morbidity and mortality. The study aim to evaluate the ... Read More »
Attenuating Effect of Icariin, a Flavanoid in Partial Sciatic Nerve Ligation Induced Neuropathic Pain in Rats: An Evidence of Anti-Oxidative, Anti-Nociceptive and Neuroprotective Activity
Swapna Pokkula*1, Santhrani Thaakur2, Lavanya Yaidikar3 1Department of Pharmacology, Browns College of Pharmacy, Khammam, Telangana, India. 2Department of Pharmacology, Sri Padmavathi Mahila Visvavidyalayam, Tirupati, Andhra Pradesh, India. 3Seven Hills College of Pharmacy, Tirupati–517502, Andhra Pradesh, India A B S T R A C T Neurodegeneration of the central and peripheral nervous system causes neuropathic pain. The present study has been ... Read More »
A Validated Reverse Phase Stability-Indicating HPLC Method Forbortezomib in the presence of degradation products and process-related impurities
Jagadeswara Rao K1,2, Mohan B2,3, Venugopal NVS3, Murali Mohan SV2 and *Rama Rao Malla1 1Department of Biochemistry, Cancer Biology Lab, GIS, GITAM University, Visakhapatnam, India 2Analytical Research and development Department, Shilpa Medicwere Limited, India 3Department of Chemistry, GIS, GITAM University, Visakhapatnam, India A B S T R A C T Degradation cycle of bortezomib was established as per ICH guidelines ... Read More »
Development of Enhanced Site Specific Periodontal Drug Delivery Systems for Minocycline HCl and Ciprofloxacin Films
Mukamalla Suresh*, Rohit Saraswat School of Pharmacy, OPJS University, Churu, Rajasthan A B S T R A C T Ciprofloxacin hydrochloride, fluoroquinone antibiotic and Minocycline hydrochloride, tetracycline antibiotic that could be used in the treatment of periodontitis for localized therapy. The ciprofloxacin film was formulated using biodegradable polymer, gelatin and sodium alginate with poly ethylene glycol (PEG) 400. The film ... Read More »
Nephro-protective Activity of Methanol Extract of “Cassia tora’’ Seeds in Cisplatin Induced Nephrotoxicity in Mice
Raghu Ram.A1*, Dr. Rohit Saraswat2, D. Yashwanth Kumar3 1,3Research Scholar, School of Pharmacy, OPJS University, Churu, Rajasthan 2Research Supervisor, School of Pharmacy, OPJS University, Churu, Rajasthan A B S T R A C T Kidneys have sensitive tasks, especially when they deal with unwanted substances, which have to be cleared from the system, principally toxins. Kidneys play an important role ... Read More »
Formulation and Evaluation of Metformin Hydrochloride and Linagliptin Immediate Release Tablets
P. Ramya*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India-518218 A B S T R A C T The main objective of the work is to design and develop immediate release tablets of Metformin Hydrochloride and Linagliptin in combination using different granulating agents and to perform suitable studies for the development ... Read More »
Design Formulation and Evaluation of Lansoprazole Mouth Dissolving Tablets
R. Kavitha*, C.S. Pasrameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India-518218 A B S T R A C T The aim of the present work is to investigate the possibility of preparing mouth dissolving tablet containing Lansoprazole by direct compression method. Mouth dissolving tablets are innovative tablet technology where the dosage form ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Tezacaftor and Ivacaftor by RP-HPLC Method
Chitraju Prathyusha, P. Sabiya*, B. Poornima Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupathi, A.P, India. A B S T R A C T The aim of present research work made to develop and validate simultaneous estimation of Tezacaftor and Ivacaftor was done by RP-HPLC. The optimized mobile phase was consists of Acetonitrile: Phosphate buffer pH 2.5 mixed in ... Read More »
Development of new simultaneous RP-HPLC method for the estimation of Dapagliflozin and Saxagliptin in tablet dosage form
M. Kavitha*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr.K.V.Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim of present research work made to develop and validate RP-HPLC method for the simultaneous estimation of Dapagliflozin and Saxagliptin in bulk and combined dosage form. The optimized mobile phase was consists of 0.1% ... Read More »
