Wednesday , 17 July 2024

Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Pregabalin and Methylcobalamin in Formulation by QBD Approach

Aasadi Balaji*, G. Dharmamoorthy, G. Aruna, KV Nanda Kumar, P. Jaya Chandra Reddy Krishna Teja Pharmacy College, Chadalawada Nagar, Renigunta Road Tirupati-517506 ABSTRACT By considering the current regulatory requirement for an analytical method development, a simple, precise, accurate, linear and rapid Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method for the simultaneous quantitative estimation of Pregabalin 75mg and Methylocobalamin 750µg ... Read More »

Photochemical Study of Medicinal Compound (N-2 (thaizolyl) sulfanilamide,)

Meena Chourey* Oriental Institute of Science and Technology Bhopal, India – 462021 ABSTRACT N-2(thaizolyl) sulfanilamide, it is common hetero atoms are N,O and S.Sulphonamide are synthetic chemotherapeutic agents which contain a sulphonamide (SO2- NH2)group in their structures. The Photochemical reaction of N-2(thaizolyl) sulfanilamide it is in different medium, for example of, neutral medium, acidic medium and alkaline medium It is ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Sildenafil and Dapoxetine by Using RP-HPLC Technique

Prathap.B1*, V.HariBaskar1, B.Kumar1, D.Ramesh2, M.Maheswari1, S.Harika1, P.Sonalika1 1Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh – 524346. 2Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G Nagar-571448, Mandya, Karnataka. ABSTRACT A new RP-HPLC method was developed for the simultaneous estimation of sildenafil and Dapoxetine in pharmaceutical dosage form. The chromatographic conditions were successfully developed ... Read More »

Analytical Method Development and Validation of Paclitaxel Pharmaceutical Dosage Forms by RP-HPLC

K. Nithiyananthan1 K.V.S Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur. 2Principal, Rahul Institute of Pharmaceutical Sciences and Research, Chirala. ABSTRACT A simple, precise, accurate RP-HPLC method was developed and validated for the estimation of Paclitaxel in pharmaceutical dosage forms. An Agilent column (4.6×150mm) 5µ, flow rate was 1.0 ml/min, mobile phase ratio was Methanol: Phosphate buffer (60:40% v/v), detection wavelength ... Read More »

Method Development and Validation of Gemifloxacin by using Gas Chromatography

K. Padmalatha, Vijaya Durga. D*, Sk. Salma, N. Naga Lakshmi, Ch. Janaki, U. Sony, M. Shireen, K.V.S.S. Sahithi Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada-521108, India. ABSTRACT The aim of present research work to development of simple, rapid and cost-effective method for the estimation Gemifloxacin by using gas chromatography with flame ionization detector (GC-FID).The solutions ... Read More »

A Comparative Study of Packaging, Labelling and Container Closure Systems of Various Regulatory Bodies

V. Narasimhulu*, J. Praveen Kumar, P. Jaya Chandra Reddy Krishna Teja Pharmacy College, Tirupathi, Andhra Pradesh, India ABSTRACT Regulatory affairs professionals are key players in drug development for obtaining approvals and maintaining life cycle management of both branded and generic drugs. Packaging has been around for many hundreds of years in some shape or form, from the early days of ... Read More »

Method Development and Validation of Pregabalin Single Drug Molecule by Using UV Double Beam Spectrophotometer

K. Surendra*, P. Shankar, G. Yamini, M.V. Jeevanandham, S.MD. Shahid Afridi Rao’s College of Pharmacy, Chemudugunta, Venkatachalam, Nellore, Andhra Pradesh-524320, India. ABSTRACT The present research work was mainly focused on method development and validation for the quantification of Pregabalin in tablet formulation by using UV spectroscopy. The solvent employed for this method was distilled water and absorption maximum was found ... Read More »

Formulation and Evaluation of Oral mouth dissolving Tablets of Dapsone

B. Sireesha1, K. Sunil kumar2 1Sun Institute of Pharmaceutical Education And Research, Kakupalli, Nellore, Andhrapradesh, India. 2Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A B S T R A C T The aim of the present study is to formulate the Oral Mouth Dissolving tablets (ODT) of Dapsone using SSg, ... Read More »

Evaluation of Antiurolithiatic activity of Ethanolic Extract of Alphonsea Sclerocarpaon Ethylene Glycol Induced Urolithiasis in Rats

Vinitha.M*, Dr. P. Dharani Prasad, Dr. V. Jayasankar Reddy, Dr. P. Jayachandra Reddy Department of Pharmacology, Krishna Teja College of Pharmacy, Tirupathi-517506 A B S T R A C T Kidney stones are one of the most painful of the urologic disorders. Renal stone affect 5% to 15% of adults. In the present study the roots of Alphonsea sclerocarpa Linn ... Read More »

Development and Validation of UV-Spectroscopic Method for Estimation of Formoterol in Bulk and Pharmaceutical Dosage Form

P. Penchalamma*, G. Vikas, C. Dileep Reddy, S. Chaitanya, Shaik. Aftab, D. Narayana Rao’s College of Pharmacy, Chemudugunta, Venkatachalam, Nellore, Andhra Pradesh-524320 A B S T R A C T This UV-spectrophotometric technique is quite simple, accurate, precise, reproducible, and sensitive. The UV method has been developed for quantification of Formoterol in tablet formulation. The validation procedure confirms that this ... Read More »

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