Monday , 15 July 2024

METHOD DEVELOPMENT AND ITS VALIDATION FOR QUANTITATIVE SIMULTANEOUS DETERMINATION OF DEXAMETHASONE AND GATIFLOXACIN IN OPHTHALMIC SOLUTION BY RP-HPLC

About author : Ankit Agarwal*, Subhash Dadhich, Sunil Kumar Tiwari, Kashyap Nagariya R & D Division, Ahlcon Parenterals (I) Ltd., Bhiwadi, Rajasthan, India *e-mail: [email protected] ABSTRACT : To develop a simple, rapid and accurate HPLC method for simultaneous quantitative determination of Dexamethasone and Gatifloxacin in ophthalmic solution. Chromatographic separation was achieved with PDA detector using Inertsil C18, 250 x 4.6mm, ... Read More »

Mass Spectrometry – A vulnerable analytical tool for molecular formula & mass determination

About author : Jony Mallik* Department of Pharmacy, Southern University Bangladesh, Chittagong-4200. *e-mail: [email protected] INTRODUCTION Pharmaceutical analysis has greatest importance in pharmaceutical science, specially in terms of Research & Development (R&D), Drug-Product design, Quality Control Department of a Pharmaceutical Industry. Among the number of spectroscopic analytical techniques, Mass Spectrometry occupied a large area of whole analytical zone. The very important ... Read More »

A NOVEL APPROACH FOR DRUG DELIVERY: A MEDICATED CHEWING GUM

About author: Kalpen N Patel*, Maulika S Patel Dept. of Pharmaceutical Technology Shree Krishna Institute of Pharmacy, Shankhalpur, Becharaji, Mehsana. *e-mail : [email protected] INTRODUCTION: Medicated Chewing gum is a potentially useful means of administering drugs either locally or systemically via, the oral cavity. The Medicated Chewing gum has through the years gained increasing acceptance as a drug delivery system. Today ... Read More »

RECENT ADVANCES IN TABLETING TECHNOLOGY

About author: S. Prasanthi*  Research Scholar, Dept. of Pharmaceutical technology, AU College of Pharmaceutical Sciences, ANDHRA UNIVERSITY. A P, India *e-mail: [email protected] Introduction: Tablets, a dosage form that stood the test of time have evolved from being a simple uncoated tablet for oral administration giving immediate release, to sustained release systems that can be implanted into the body. Industrial production of tablets has ... Read More »

A COMPARISION OF ANALYTICAL METHOD VALIDATION PROCEDURES

About author: Chinmaya Keshari Sahoo* Research Scholar,Dept. of Pharmaceutics, OUCT, Osmania University,A.P, India *e-mail: [email protected] INTRODUCTION : Analytical method validation is a regulatory requirement that refers to the evaluation and proving that the selected analytical method shall ensure reproducible and reliable results adequate for the intended purpose.The process of analytical method validation should demonstrate that the method is fit for ... Read More »

Role of DPP IV Inhibitor in Type-2 Diabetes Mellitus

About author : Anup K. Chakraborty*, Umesh K. Patil Dept of Pharmaceutical Chemistry, School of Pharmacy & Research Centre, People’s University, Bhopal (M.P.), India *e-mail: [email protected] Abstract: Incretin hormones are defined as intestinal hormones released in response to nutrient ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin effect is mainly caused by two peptide hormones, glucose-dependent insulin ... Read More »

PHARMACOGNOSTICAL STUDY AND LOCALIZATION OF TANNIN IN PENTATROPIS CAPENSIS LEAF- AN EXTRA PHARMACOPOEIAL PLANT

About author : Chowdhury Saikat*, K Nishteswar, Harisha CR I.P.G.T. & R.A.  Gujarat Ayurved University, Jamnagar, India *e-mail : [email protected] ABSTRACT:                                                                  Pentatropis capensis Linn. f. (Bullock) is a straggler twining on thorny shrubs and trees, belonging to the family Asclepiadaceae, commonly known as Kakanasa, distributed throughout Bengal and Western Peninsula. Till there was no data regarding the detailed pharmacognostical, ... Read More »

DETAIL COMPARATIVE MACRO AND MICRO MORPHOLOGICAL STUDY OF KARPAS (Gossypium herbaceum Linn.) AND RAKTA KARPAS (Gossypium arboreum Linn.) LEAF AND STEM.

About author : Dr. Ananta krushna palei*, Harisha C.R IPGT & RA, Gujarat Ayurveda University, Jamnagar, India *e-mail:[email protected] ABSTRACT Gossypium herbaceum Linn. known as Karpasa. Gossypium arboreum Linn., commonly known as Rakta Karpasa. both belongs to the family Malvaceae. Karpasa  is widely used in Ayurveda for the treatment of diseases like post-puerperal haemorrhage, dysmenorrhoea, diarrhoea, hyperpiesia, dysentery etc.  and for ... Read More »

FORMULATION AND EVALUATION OF ETHYLCELLULOSE COATED MICROCAPSULES FOR CONTROLLED RELEASE OF PARACETAMOL

About author: Navneet Kumar Verma* Department of Pharmacy, Rameshwaram Institute of Technology and Management Lucknow (U.P), India *e-mail- [email protected] ABSTRACT: The objective of the study is to evaluate ethylcellulose as a coat for controlled release microcapsules of paracetamol. Ethylcellulose coated microcapsules were prepared by an emulsion-solvent evaporation method employing different proportions of core and coat and the microcapsules were evaluated ... Read More »

Anti-atherogenic effects of HDL

About author : Amir Khan*,  Anchal Rana *Dept. of Biotechnology & Biochemistry Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences & Research, Dehradun, India *e-mail: [email protected] Introduction : High Density Lipoprotein (HDL) is the most potent lipid predictor of coronary artery disease risk in men and women above 49 years of age. Every 1 mg/dl increment in HDL  is ... Read More »

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