About author Reddi Prashanth, Dr. Hindustan Abdul Ahad, Naresh babu G, Mohammed Ishaq B, Anil Kumar K PG department of Industrial Pharmacy, Balaji College of Pharmacy, Anantapur, AP, India E-mail: [email protected] Abstract The aim of the present work is to design bilayer tablets containing Losartan Potassium for immediate release using sodium starch glycolate as super disintegrant and Metoprolol succinate for ... Read More »
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Spectrophotometric Simultaneous Estimation of Valsartan and Hydrochlorothiazide in Pharmaceutical Dosage Form using Mixed Hydrotropic Solubilisation Approach
About author Jyoti Vilas Jadhav*, Kishorkumar Burade Govt. College of Pharmacy, Vidyanagar Karad, Satara, Maharashtra- 415124, India Email: [email protected] Abstract Two validated UV spectrophotometric methods for the simultaneous estimation of Valsartan and Hydrochlorothiazide in pure powder and in two component tablet dosage form have been developed, utilising simultaneous equation and absorbance ratio method. The ... Read More »
A Quantitative Structure-Activity Relationship Study of Caffeic Acid Amides as Selective Inhibitors of Matrix Metalloproteinase
About author Prithvi Singh* Department of Chemistry, S.K. Government Post-Graduate College, Sikar-332 001, India E-mail: [email protected] Abstract A quantitative structure-activity relationship (QSAR) study is carried out on caffeic acid amides as the inhibitors of matrix metalloproteinase (MMP). The inhibition action, for the sub-type MMP-9, is quantitatively analyzed following the non-parametric (Fujita-Ban) and parametric approaches. The Fujita-Ban analysis has identified the substituents ... Read More »
Biological Evaluation of Some Newly Synthsized Thiazolidinone Derivatives for their Analgesic Activity
About author Pravesh Gangwar*, Dr.Pankaj Sharma, Dr. Birendra Shrivastava. Jaya Sharma, Shikha Sharma Derartment of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India. E-mail: [email protected] Abstract Two new thiazolidinone derivatives were prepared by brominating 1-acetylnaphthalene in chloroform followed by condensation with substituted benzaldehyde thiosemicarbazones using ethanol to get 4-naphthalen-1-yl-2-{2-[(substituted phenyl)methylidene]hydrazino}-1,3-thiazoles. These thiazole derivatives were then cyclized to title compounds by ... Read More »
Synthesis and Characterization of New Thiazolidinone Derivatives and Screening for Their Anti-Inflamatory Activity
About author Pravesh Gangwar*, Dr.Pankaj Sharma, Dr. Birendra Shrivastava.Jaya Sharma, Shikha Sharma Department of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India. E-mail: [email protected] Abstract In the present study, a thiozolidinones derivatives were synthesized by the 1-actynaphthalene. 1-actynaphthalene on brominating with chloroform gives 1-bromoactynaphthalene which was reacted with substituted benzaldehyde thiosemicarbazone in ethanol as a solvent give 4-naphthalen-1-yl-2-{2-[(substituted phenyl) methylidene] ... Read More »
Redox Reactions of Cobalt (III) Complexes of A-Hydroxy acids by Pyridinium Dichromate in Surfactants
About author B. Mohammed Nawaz* PG and Research Department of Chemistry, Islamiah College, Vaniyambadi-635752,Tamil Nadu, India E.mail: [email protected] Abstract The kinetics of one electron transfer mode seems to be unavailable for PDC with Cobalt (III) bound and unbound complexes of α-hydroxyacids in surfactant medium, PDC oxidizes Cobalt(III) bound and unbound α-hydroxyacids. It rules out the synchronous C-C bond fission and ... Read More »
Eudragit a Versatile Polymer: A Review
About author Ishan Patel, Tiwari Ajaykumar, Dr. B.S. Srivastav Deparment of Pharmaceutical Science, Jaipur National University, SADTM Campus, Jaipur-302025. E-mail: [email protected] Abstract One would always like to have an ideal drug delivery system that will possess three main properties: It will be a single dose for the whole duration of treatment. It will deliver the active drug directly at the site ... Read More »
Regulatory Requirements for Import and Registration Lafutidine Tablet in India
About author Ramesh Chand Sharma*, Rajesh Saini, Mr. Ranjan Bairwa, Dr. Birendra shrivastav Department of pharmaceutical sciences, Jaipur National University, SADTM Campus, Jaipur-302025. India. E-mail: [email protected] Abstract Lafutidine is a histamine H2 receptor antagonist, the gastro protective effect of which is related to its antisecretory activity and its ability to activate a sensory neuron-dependent mechanism of defense. The present study ... Read More »
To Study Regulatory Requirements for Marketing Authorization of Febuxostat Tablet in India
About author Rajesh Saini*, Dr. Birendra shrivastav, Ramesh Chand Sharma, Dr. Rajendra Songra Department of pharmaceutical sciences, Jaipur National University, SADTM Campus, Jaipur-302025. India. E-mail: [email protected] Abstract Febuxostat has been approved for the treatment of hyperuricemia in patients with/without gout. This meta-analysis and systematic review assessed the efficacy and tolerability of febuxostat in hyperuricemia patients with/without gout. Major electronic databases were searched ... Read More »
Aloe Vera Gel Review
About author Abhilash A*, Prabhu Raj KJ, Gopi Krishna B,Hemalatha M, Dr. Hindustan Abdul Ahad B. Pharmacy, Balaji College of Pharmacy, Anantapur, AP, India. E-mail: [email protected] Abstract Aloe vera, commonly known as Barbados or Curaçao Aloe, is an herbal medicine with a long tradition of use by a variety of cultures. The succulent plant grows in arid and subtropical climates ... Read More »