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Panga Latha1*, K. Umasankar1, M. Alagusundaram1, M. Srikanth Reddy1, G. Devi Nagajyothi1, M. Mallika1, Jagadesh kumar yadav.K2 1Department of pharmaceutics, Krishna Teja College of Pharmacy, Tirupathi, Andhra Pradesh, India 2Department of pharmaceutics, Sree Vidyanikethan College of Pharmacy, Tirupathi, Andhra Pradesh, India Abstract Amylodipine besylate is a anti-hypertensive drug (or) blood pressure reducer, having the 64% bio-availability .in the present study focus ... Read More »
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Isatine: A Versatile Heterocyclic Molecule
Shailee Tiwari* Department of Pharmaceutical Chemistry, YB Chavan College of pharmacy, Aurangabad, India Abstract Heterocyclic compounds are present in many of our medicines used today. This article gives detailed information on isatine which is one of the versatile heterocyclic molecule. It is a synthetically versatile molecule, a precursor for a large number of pharmacologically active compounds. Isatin and its derivatives ... Read More »
Solid Dispersion-A Strategy for Improving the Solubility of Lipophilic Drugs
Krishna Moorthy S.B,*1 Sandeep. J2, Rajalakshmi.R1, Rubiya SK1, Saddam hussain. SK1 1Department of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupathi, Andhra Pradesh, India. 517102. 2Department of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupathi, Andhra Pradesh, India. 517503. Abstract Improving oral bioavailability of drugs those given as solid dosage forms remains a challenge for the formulation scientists due to solubility ... Read More »
Phytochemical screening and Antidiabetic activity of extracts of Citrullus lanatus rind in Alloxan-Induced Diabetic Albino Mice
Umar Muhd Sani* Chemistry Department, Nigeria Police Academy, P.M.B. 3474, Wudil, Kano State Abstract A number of plants products among which the protein-rich Cucurbitaceae seeds are commonly used in traditional medicine with increasing acclaimed efficacy against diabetes mellitus. In this study the anti-diabetic effect of ethanol and petroleum ether extracts of Citrullus lanatus (watermelon) rind in alloxan-induced diabetic mice have ... Read More »
Efficient Computational Analysis of 4-(butan-2-ylideneamino)-N’-ethylidenebenzohydrazide Derivatives for Design of Anti microbial agents
Manocha Nimita, Bahrani Pankaj, Jain Neha* Department of Pharmaceutical Chemistry, Swami Vivekanand College of Pharmacy, Indore M.P, India-452001 Abstract QSAR studies were performed on selected series of 4-(butan-2-ylideneamino)- N’-ethylidenebenzohydrazide derivatives. The best quantitative structure activity relationship models were further validated by LOO method of cross-validation. The study of best model shows that the steric property like Radius (Rad) contributed negatively ... Read More »
Removal of Carbamazépine (CBZ) from aqueous solution using Cuttlefish bones
Hassen Khazri*1,2, Ibtissem Ghorbel-Abid1,2, Rafik Kalfat1, Malika Trabelsi-Ayadi2 1Laboratory of Methods and Techniques of Analysis (LMTA), National institute of Physico-chemical Analysis (INRAP), Technological Pole-2020, Sidi Thabet, ARIANA Tunisia. 2Laboratoire des Applications de la Chimie aux Ressources et Substances Naturelles et a` l’Environnement (LACReSNE), Faculty of Sciences of Bizerte, Zarzouna 7021, Tunisia Abstract Pharmaceutical compounds have an emerging group of organic ... Read More »
A Green Synthesis of xanthone and thioxanthone Derivatives by ZrCl4 in Ionic liquid under Microwave Irradiation
M. A. Nasseri*, E. Vahedi, B. Zakeri Nasab, A. Allahresani Department of Chemistry, College of Sciences, University of Birjand, Birjand- 97175-615, Iran Abstract A mild and green procedure is presented for the preparation of biologically interesting hydroxyl xanthones and hydroxyl thioxanthones via condensation of salicylic acid / thiosalicylic acid with phenol derivatives in the presences of ZrCl4 under microwave-assisted ionic ... Read More »
Evaluation of antidiabetic activity of methanolic leaves extract of Lagerstroemia microcarpa in streptozotocin induced diabetic rats
Revitha. L, C.D. Shaji Selvin* Sree krishna College of Pharmacy and Research Centre, Parassala, kerala, India Abstract In the present study, the effect of alcoholic leaves extract of Lagerstroemia microcarpaon blood glucose,plasma insulin, and carbohydrate metabolic enzymes were studied in experimental diabetes. Diabetesmellitus was induced by a single intraperitoneal injection of STZ (60 mg/kg bw). ... Read More »
Kinetic Studies of Micelle-Assisted Redox reactions in aqueous Media
Asok K. Jana*1, G. Subashini1 and Papiya Jana2 1Department of Chemistry, Kanchi Mamunivar Centre for Post-Graduate Studies, Pondicherry-605008, India 2Department of Chemistry, Sri Manakula Vinayagar Engineering College, Pondicherry 605107, India Abstract The rate constant of three redox reactions: i) Fe3+ — H2O2, ii) S2O8 2-—I– and iii) BrO3–—I– were determined in aqueous media in the absence and presence of surfactants: ... Read More »
1-Bromobenzimidazole Oxidation of Aliphatic Alcohols -A Kinetic Perspective
B. Ramkumar*1, V. Santhosh Kumar2 and M. Rukmangathan2 *1PG and Research Department of Chemistry, Government Arts College, Thuvakudimalai, Tiruchirappalli, Tamil Nadu, India–620022 2Department of Chemistry, Arasu Engineering College, Kumbakonam, Tamil Nadu, India–612501 Abstract The kinetics of oxidation of aliphatic alcohols by 1-bromobenzimidazole (BBI) has been studied in aqueous acetic acid medium in presence of mercuric acetate. The order of the reaction ... Read More »
