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Vasanthi. J* and S. Binukumari PG and Research Department of Zoology, Kongunadu Arts and Science College, Coimbatore, TamilNadu ABSTRACT The wide spread use of synthetic organic pesticides over decades has let to their frequent exposure in the environment. Also acute and chronic exposures of humans to pesticides occur during their commercial production and their application. Synthetic pesticides are deliberately ... Read More »
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Fluorescence resonance energy transfer (FRET) based high throughput drug screening for the determination of antineoplastic activity of natural compounds from herbs
Sharmistha Gupta1 and Mithun Mukherjee2 1West Bengal State Council of Science and Technology, West Bengal-India 2Ramakrishna Vivekananda Mission Institute of Advanced Studies, West Bengal-India ABSTRACT Objectives: In the present experiment a very useful cell-based high throughput screening method that uses a novel bio-sensor which specifically identifies apoptosis based on fluorescence resonance energy transfer technology. Methodology: A stable HeLa cell line ... Read More »
Acute and Sub-Chronic Toxicity Studies of Recombinant Exenedin-4 in Rats
Sumasri Guntupalli*1, Gowthami Vangala2, Venugopalaiah Penabaka3, Pasupuleti Naresh3 1Department of Pharmacology, Shri Vishnu College of Pharmacy, Andhra Pradesh, India 2Department of Biotechnology, Virchow Biotech Private Limited, Hyderabad, India 3Department of Pharmaceutics, Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh, India-524346 Abstract The acute and sub-chronic toxicity effects of recombinant Exenedin-4 were investigated when administered intravenously and subcutaneously to Sprague Dawley (SD) Rats. ... Read More »
A Review on Alzheimer’s Disease
M.V. Sai Lalith kumar*, Y.N. Sujitha, S. Sudheer, K. Siva, Madhavi latha Nrayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh, India Abstract Alzheimer’s disease, is also known in medical literature as Alzheimer disease, and is the most common form of dementia, which is not curable that as it progress and eventually death. Most of this disease is seen in the old ... Read More »
Formulation and Evaluation of Glimepiride Fast Dissolving Tablet
Ashwini V*, Poojitha U, Surekha R, Geetha G, Srinath B Raghavendra Institute of Pharmaceutical Education and Research, Ananthapuramu, AP, India. Abstract The objective of this work was to prepare Glimepiride (1mg) fast dissolving tablets by wet granulation method. Glimepiride was the drug of choice because of its low dose. The prepared Glimepiride FDT were found to have faster onset of ... Read More »
Prevalance of HIV and Syphilis among Patients Attending ICTC Center in a Multispeciality Hospital in Heritage City
Sumana MN, Arnaw Kishore* Department of Microbiology, JSS Medical College and Hospital, JSS University, India Abstract It is estimated that globally, 34.0 million [31.4 million–35.9 million] people were living with H.I.V at the end of 2011. According to W.H.O. estimates, 15% (50 million) of the 340 million new annual sexually transmitted infection (S.T.I.) cases are in India, and 44% (151 ... Read More »
A Novel validated RP-HPLC method for the estimation of “Rupatadine” in its Bulk and Pharmaceutical Dosage forms
CH. Naveen Kumar*, Arvapalli Rajani, Vemula Madhavi Latha, Vijaya Kuchana Department of Pharmaceutical Analysis and Quality Assurance, Teegala Krishna Reddy College of Pharmacy, Hyderabad, India Abstract A Novel Reverse Phase High Performance Liquid Chromatography (RP-HPLC) method for the Estimation of “Rupatadine” has been developed. The developed method was found and proved to be a better one than the already existing ... Read More »
Process Validation of Terbinafine Hydrochloride Tablets and Blend
Kullayappa C*, Naresh G, Muneer S, Hindustan Abdul Ahad Department of Pharmaceutics, Balaji College of Pharmacy, Ananthapuramu, AP, India Abstract Quality is the primordial intention for process validation is the means of ensuring and providing documentary evidence that processes within their specified design parameters are capable of repeatedly and reliably producing a finished product of required quality. In this study ... Read More »
Simple Stability Indicating Methods for Metaxalone by RP-HPLC
S. Praveena, S. Muneer*, B. Mohammed Ishaq, Hindustan Abdul Ahad, Murali D PG department of Pharmaceutical Analysis, Balaji College of Pharmacy, Anantapur, AP, India Abstract A novel stability-indicating high-performance liquid chromatographic assay method was developed and validated for Metaxalone in the presence of degradation products generated from forced decomposition studies. Metaxalone is a skeletal muscle relaxant. The method was based ... Read More »
Formulation and Evaluation of Immediate Release Donepezil Tablets
Taj khan H*, Hindustan Abdul Ahad, Naresh G, Sreekanth K PG Department of Pharmaceutics, Balaji college of pharmacy, Ananthapuramu-515 001, Andhra Pradesh, India Abstract The study was undertaken with an aim to develop an optimized formulation of anti-Alzheimer, Donepezil HCl by oral drug delivery. Preformulation studies were conducted to know the drug excipients compatibilities. Based on the results, suitable excipients ... Read More »
