Monday , 15 July 2024

Life Cycle Management of Drugs – An Extensive Review

Venugopal.A*, Vijayaraj.S, Kalyana Chakravarthi.G, Saritha.M, Shakeerbasha.S Department of Pharmaceutical Analysis, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, A. Rangampet, Tirupathi–517102, Chitoor (DT), Andhra Pradesh, India. A B S T R A C T Lifecycle management refers to extend the market exclusivity period. The exclusivity period is increasing the marketing period by extending the patent life. Patenting is common type ... Read More »

Method Development and Validation of Nebivolol by RP-HPLC

Naga Jyothi. C*, Gummi Vishwanth, P. Sunitha Pharmaceutical Analysis and Quality Assurance,   JNTUH, Kukutpally, Hyderabad, India A B S T R A C T An isocratic reversed-phase high performance liquid chromatographic method was established for the estimation of Nebivolol in tablet dosage form. The chromatographic conditions were successfully developed for the estimation of Nebivolol by using Develosil C18 column (150×4.6mm, ... Read More »

Design and Evaluation of Fast Dissolving Tablets of Fexofenadine by Using Novel Super Disintegrants

B. Venkateswara Reddy*, G. Srikanth, K. Navaneetha Department of Industrial Pharmacy, St.Paul’s College of Pharmacy, Hayathnagar, Hyderabad, R.R.Dist-501510, India A B S T R A C T The purpose of this research was to formulate tasteless complexes of Fexofenadine Hydrochloride with Amberlite IRP-64 and to formulate tasteless complex into Orally-Disintegrant tablets (ODT) for the treatment of allergic rhinitis & chronic ... Read More »

Design and Evaluation of Entecavir Sustained Release Microspheres

B. Venkateswara Reddy*, G. Shankar, K. Navaneetha Department of Industrial Pharmacy, St.Paul’s College of Pharmacy, Hayathnagar, Hyderabad, R.R.Dist-501510, India A B S T R A C T The present research work is aimed to design oral twice a daily sustained release microspheres of Entecavir, used for the treating or preventing Hepatitis B which can release the drug for 10 to ... Read More »

Method Development and Validtion of Melphalan Injection by RP-HPLC Method

Gummi Vishwanth*, P. Sunith, Naga Jyothi. C Pharmaceutical Analysis and Quality Control,   JNTUH, Hyderabad, India A B S T R A C T A simple, rapid, sensitive, accurate and precise RP-HPLC method has been developed and validated for the estimation of melphalan in injection dosage form. The mobile phase used was a combination of Methanol, Acetonitrile, TEA in the ratio ... Read More »

Anti-Depressant Activity of Alstonia Venenata R.Br Stem Bark Extracts in In-vivo Methods

C. Pradeep Kumar*, T. Sravanthi, Dr. Vijaya Kuchana, CH. Maheswara Reddy Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana, India A B S T R A C T The ethanolic extract of Alstonia venenata R.Br stem bark was subjected for phytochemical investigation and LD50 studies. It was found that ethanolic extract contained reducing sugars, proteins. Aminoacids, flavonoids, phenolic compounds and ... Read More »

Method Development and Validation studies of Pregabalin Drug by RP-HPLC Method

Eswara Rao Bammidi*1, Vaikuntarao Lakinani1, Subrahmanyam Lanka1, Mallikarjun Rao Duvvada2 1Departmernt of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, A.P., India 2Departmernt of Environmental Sciences, GITAM Institute of Science, GITAM University A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of related substances in Pregabalin in bulk and ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Ambroxol HCL and Levocetrizine in Its Bulk and Dosage Form by RP-HPLC

R. Vivek*, Dr. T. Rama Mohan Reddy, Dr. V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Hyderabad, Rangareddy, India A B S T R A C T A simple Reverse phase liquid chromatographic method has been developed and subsequently validated for simultaneous determination of Levocetirizine and Ambroxol HCl in combination. The separation ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Albendazole and Ivermectin Tablet of Dosage Form by RP-HPLC

B. Saidulu*, G. Usha Sree, Dr. V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Hyderabad, Rangareddy, India A B S T R A C T A reverse phased liquid chromatography (LC) method was developed and validated for simultaneous estimation of albendazole and ivermectin in tablet dosage form. The isocratic LC analysis was ... Read More »

A Novel RP-UPLC Method for the Simultaneous Estimation of Domperidone and Rabeprazole in Pharmaceutical Dosage Form

K. Spandana*1, N. Venkatesh1, K. Suresh2, U. Sambamoorthy1 1SARC – (Scientific and Applied Research Center) Hyderabad, India 2Pratishta Institute of Pharmaceutical Sciences, Durajpally, Suryapet, Hyderabad, India A B S T R A C T A simple, accurate, rapid, precise and novel Reverse phase Ultra Pressure liquid chromatographic method has been developed and validated for simultaneous determination of Domperidone and Rabeprazole ... Read More »

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