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K. Lavanya*, Ramesh Dhani, T. Sairajitha, K. Sravani, G. Tharunasree, G. Gnanaprasuna Ratnam Institute of Pharmacy, Pidathapolur, Muthukur (M), Nellore, Andhra Pradesh, India-524346 A B S T R A C T In recent years there have been a number of technological break throughs that have allowed for clinical trails in gene therapy to be initiated. In combination with the genome ... Read More »
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A Scientific Report on Alzheimer’s disease
T. Sairajitha*, Ramesh Dhani, K. Sravani, G. Tharunasree, k, lavanya, G. Gnanaprasuna Ratnam Institute of Pharmacy, Pidathapolur, Muthukur (M), Nellore, Andhra Pradesh, India-524346 A B S T R A C T Alzheimer’s disease (AD) is the most common cause of dementia worldwide. The etiology is multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential rise in the number ... Read More »
DFT Calculations for the Alkaloids Present in Erythrina Varigata Species
Dr (Mrs). G.Valli*2 and A. Jayalakshmi1 1Department of Chemistry, S.F.R. College, Sivakasi, Tamilnadu, India 2Associate Professor & Head, Department of chemistry, S.F.R. College, Sivakasi, Tamilnadu, India A B S T R A C T The alkaloids isolated from Erythrina varigata species were found to exhibit various pharmacological properties. In order to predict the lead compounds among the ten alkaloids chosen ... Read More »
Synthesis of N-Substituted Tetrahydrocarbazoles and Anticonvuslant Activity of Synthesised Compounds
Subrahmanyam Lanka* 1, Vaikuntarao Lakinani1, Eswara Rao Bammidi1, Siva Rama Rao Kakani2 1Department of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, India 2Noida Internatioanl University, NOIDA, U.P A B S T R A C T Thrust in the preparation of new heterocyclic molecules is increasing due to their proven significant biological activities. The paramount importance of heterocycles such as indoles ... Read More »
In-vitro Assessment of Free Radical Scavenging Anti-Inflammatory Potential and Phytochemical Analysis of Ethyl Acetate Leaf Extract of Manilkara Zapota
K. Kamalakararao1, K. Krishna Chaitanya1, Y.N. Sastry1, Dr. Ch. Surekha1, Dr. S.B. Padal2, Dr. D. Govinda Rao1 1Department of Biochemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, India 2Associate Professor, Department of Botany, Andhra University, Visakhapatnam, Andhra Pradesh, India A B S T R A C T Phytochemical analysis had become a vital aspect in screening of valuable phytoconstituents. ... Read More »
Development and Characterization of Bioadhesive Gel Incorporated Microencapsulated Ketorolac Tromethamine for Periodontal Therapy
P. Parveen*, Dr. A. Seetha Devi Department of pharmaceutics, Hindu College of Pharmacy, Amaravathi Road, Guntur-522002, Andhra Pradesh, India A B S T R A C T To develop and characterize bioadhesive gel incorporated Ketorolac tromethamine loaded microspheres in order to sustain, localize and target drug action in periodontal pockets for more than 6hrs. Ketorolac tromethamine loaded microspheres was prepared ... Read More »
Biochemical Evaluation of Ash Value of Some Medicinal Plants of Genus Terminalia (Combretaceae) of Marathwada Region in Maharashtra
1Kadam V.B, 1Salve S.B, 1Deore S.V, 2Medhane V. J and 3Gaikwad V.B 1P. G. Dept. of Botany & Research Centre, K.T.H.M. College, Nasik–422 002 2P. G. Dept. of Chemistry & Research Centre, K.T.H.M. College, Nasik – 422 002 3Director, B.C.U.D., Savitribai Phule Pune University, Pune, India A B S T R A C T The seasonal variation of total ash, ... Read More »
Formulation and Evaluation of Niosomes of Valacyclovir Hydrochloride
A. Ankarao, CH. Sowjanya*, Dr.A. Seetha Devi, V. Vasu Naik, A. Rajesh Department of Pharmaceutics, Hindu College of Pharmacy, Amaravathi Road, Guntur A B S T R A C T Valacyclovir hydrochloride niosomes were prepared by thin film hydration and ether injection process with different ratios of (1:2:2, 1:4:2) drug and and Span-80 ,span 20(Non-ionic surfactant) cholesterol. The niosomes prepared ... Read More »
Molecular Properties and Bio-Activity Score of Alkaloids in Erythna Varigata Leaves to find Lead Compound
Dr (Mrs). G.Valli*2 and A. Jayalakshmi1 1Department of Chemistry, S.F.R. College, Sivakasi, Tamilnadu, India 2Associate Professor & Head, Department of chemistry, S.F.R. College, Sivakasi, Tamilnadu, India A B S T R A C T Molecular properties and bio-activity score of alkaloids present in erythrina varigata leaves were calculated using molinspiration software. Mi Log P values of these compounds were found ... Read More »
Sodium hypophosphite catalyzed synthesis of bis (indolyl) methanes in aqueous medium
Rasokkiyam Elayarajaa,b and R. Joel Karunakaranb* aResearch and Development Centre, Orchid Chemicals and Pharmaceuticals Ltd., Shozhanganallur, Chennai-600119. India. bDepartment of Chemistry, Madras Christian College, Tambaram, Chennai-600059, India. A B S T R A C T A mild method of sodium hypophosphite catalyzed synthesis of bis(indolyl)methanes has been described. This electrophilic bisubstitution reaction between indole and aldehyde were carried out in ... Read More »
