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S. Murali Krishna, Y. Padmalatha, L.K. Ravindranath Department of Chemistry, S.K. University, Anantapur-515003,A.P, India A B S T R A C T The article is aimed to discuss characterize and screening the biological activity of a series of Azetidinone as a Core Biological evaluation Agent. Azetidinones are of great biological interest, especially as anti-tubercular antibacterial. The important and structural diversity ... Read More »
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Analytical Method Development and Validation of Simultaneous Estimation of Tramadol, Paracetamol, Domperidone in Tablet Dosage Form by RP-HPLC
Nagaraju.Y*, A. Ajitha and Uma Maheshwar Rao. V Departmentof Pharmaceutical Analysis, CMR College of Pharmacy, Ranga Reddy-501401, India A B S T R A C T A simple reverse phase high pressure liquid chromatography (RP-HPLC) method has been developed and validated for simultaneous estimation of tramadol paracetamol and domperidone in tablet dosage forms. The compounds were separated on inertsil C-18 ... Read More »
Molecular Properties and Bio-Activity Score of Alkaloids in Erythna Varigata Leaves to find Lead Compound
Dr (Mrs). G.Valli*2 and A. Jayalakshmi1 1Department of Chemistry, S.F.R. College, Sivakasi, Tamilnadu, India 2Associate Professor & Head, Department of chemistry, S.F.R. College, Sivakasi, Tamilnadu, India A B S T R A C T Molecular properties and Bio-Activity score of alkaloids present in erythrina varigata leaves were calculated using molinspiration software. MiLog P values of these compounds were found to ... Read More »
Evaluation of Anti Ulcer effect of Polyalthia Longifolia Leaves in Albino Rats
Bhupalam Pradeepkumar1,Y Padmanabha Reddy1, N Devanna1, K Somasekhar Reddy1, A Sudheer1, G Naresh Babu2 1Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu-515721, Andhra Pradesh, India. 2Balaji College of Pharmacy, Anantapuramu-515001, Andhra Pradesh, India. A B S T R A C T The anti ulcer activity of Polyalthia longifolia has been carried out in albino rats. Antiulcer activity of ethanolic extract ... Read More »
Formulation and Evaluation of Compressed Coated Tablets of Mosapride Citrate for Colonic Delivery
Yeswanth Reddy Musukula* Department of Pharmaceutics, Synapse Life Sciences, Nakkalagutta, Hanamkonda, Warangal, Telangana, India A B S T R A C T The objective of the present research study is to develop compression coated tablets of Mosapride citrate with a view of minimizing the drug release in the physiological envinorment of stomach and small intestine and to ensure maximum drug ... Read More »
One Pot Synthesis and Biological Activities of Schiff Base
P. Venkateswara Rao, A.V. G.S. Prasad*1, P.S.S. Prasad *2 1Department of Chemistry, Nizam College (Autonomous), Hyderabad, Telangana, India. 2Drug Control Administration, Hyderabad, Telangana, India. A B S T R A C T In the present study an intermolecular reductive Schiff base formation from nitroarene and benzaldehyde to yield diarylimine is carried out in the presence of iron powder and ammonium ... Read More »
Cascade Synthesis and Biological Activities of Schiff Base
P. Venkateswara Rao, A.V.G.S. Prasad*1, P.S.S. Prasad*2 1Department of Chemistry, Nizam College (Autonomous), Hyderabad, Telangana, India. 2Drug Control Administration, Hyderabad, Telangana, India. A B S T R A C T In the present study an intermolecular reductive Schiff base formation from nitroarene and benzaldehyde to yield diarylimine is carried out in the presence of iron powder and ammonium chloride. New ... Read More »
Economic Synthesis and Characterization of Schiff Base and Metal Complexes
P. Venkateswara Rao, A.V.G.S. Prasad*1, P.S.S. Prasad*2 1Department of Chemistry, Nizam College (Autonomous), Hyderabad, Telangana, India. 2Drug Control Administration, Hyderabad, Telangana, India. A B S T R A C T In the present study an intermolecular reductive Schiff base formation from nitroarene and benzaldehyde to yield diarylimine is carried out in the presence of iron powder and ammonium chloride. New ... Read More »
Development and Evaluation of Carvedilol Fast Disintegrating Tablet by using Superdisintegrants and Solid Dispersion Technique
Hyma.P*, Mahesh.M Scientific and Applied Research Center, Hyderabad, Telangana, India A B S T R A C T Carvedilol is a poorly water soluble oral antihypertensive agent. An attempt has been made to develop fast dissolving the tablet of carvedilol direct compression and solid dispersion technique the solid dispersion of carvedilol with peg-4000(1:4 molar ratio) by fusion extrusion method with ... Read More »
Impact of rickettsial bacterial disease on immune system
Impact of rickettsial bacterial disease on immune system Amit Gupta1 and Sushama R Chaphalkar1, 2* 1Department of Immunology, Vidya Pratishthan’s School of Biotechnology (VSBT) Vidyanagari, Baramati, Pune, India 2Director, Vidya Pratishthan’s School of Biotechnology (VSBT) Vidyanagari, Baramati, Pune, India A B S T R A C T Rickettsia belonging to the family Rickettsiales. The number of human cell types which ... Read More »
