Sunday , 14 July 2024

Synthesis and Characterization of 6-Phenylimidazo [1, 2-A] Pyridin-2-yl)-1H-Pyrazoamine Derivatives

Denish C. Karia*1, Nilay Shah2 1Assistant Professor Patel J. D. K. Science College Borsad-388540 Gujarat India  2Senior Executive, Cadila Health care Pvt. Ltd, Changodar-382219, Gujarat, India A B S T R A C T 2-amino-5-bromo pyridine was treated with ethyl bromopyruvate followed by Suzuki coupling, acetonitrile-n-Buli reaction and cyclized with hydrazine hydrate at 80°C to get 6-phenylimidazo[1,2-a]pyridin-2-yl)-1H-pyrazoamine (5). This key ... Read More »

Extraction of Gallic Acid isolated from Terminalia Chebula, Analysis by Liquid Chromatography−Mass Spectrometry and its Pharmacokinetics in Mice & Rats

Sravan Kumar Reddy Theepireddy*1, Ravikanth Veluri2, Ramakrishna Chinthala1, L. Vaikunta Rao3, Byresh Pabba2, Rathanakar Reddy Kura2, Mallikarjuna Rao Duvvada1 1Department of Environmental Studies, GITAM Institute of Sciences, GITAM University, Visakhapatnam-530045, India 2Hetero Research Foundation, Plot No 80 and 81 A.P.I.E, Balanagar, Hyderabad-500018. India. 3Department of Chemistry, GITAM Institute of Sciences, GITAM University, Visakhapatnam-530045, India. A B S T R A C ... Read More »

Synthesis and Evaluation of Sulfonylureas for Anti Diabetic Activity

Anurag Singh*1, Abhishek Agrawal1, Dr. Shantaram U2 1Nargund College of Pharmacy, Bangalore, Karnataka, India 2Deparment of Chemistry, Government College of Pharmacy, Bangalore, Karnataka A B S T R A C T Drug ,synthesis and development multidisciplinary, creative, complex and highly regulated process New drug synthesis not only done loping new chemical entities but also important for therapeutic need Diabetes mellitus ... Read More »

Method Development and Validation for Simultaneous Estimation of Isoniazid and Ethambutol by using RP-HPLC in Bulk and Pharmaceutical Dosage form

Etika Madhu*, Dr. Alagar Raja. M, K.N.V Rao,David Banji Departmernt of Pharmaceutical Analysis, Nalanda College of Pharmacy, Nalgonda, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Isoniazid and Ethambutol in bulk and pharmaceutical dosage form. The separation was carried out on a [Column: Inertsil ... Read More »

Screening of In-Vitro Antioxidant Activity of Poly Herbal Methanolic Extract

Ganta Radhika Reddy*, Dr. P Mani Chandrika, K. Shailaja, K. Priyanka, D. Ratna Kumari, B. Sandhya, T. Sarika, P. Shalini Bojjam Narasimhulu Pharmacy College for Women, Vinay Nagar, Saidabad, Hyderabad, Telangana, India. A B S T R A C T The present study was carried out to evaluate antioxidant activity of poly herbal methanolic extract of peels of Beta vulgaris (beetroot), ... Read More »

Formulation and In-vitro Evalaution of Repaglinide Controlled Release Tablets

Pravalika Segonda*, Dr. P Mani Chandrika, Safura, Saleha Sultana, Sameera Gousher, Samreen Fathima, Sameena Begum. Bojjam Narasimhulu Pharmacy College for Women, Vinay Nagar, Saidabad, Hyderabad, Telangana, India. A B S T R A C T The purpose of present research work was to prepare and evaluate the controlled release tablets of Repaglinide. Direct compression method was used to prepare the tablets ... Read More »

Synthesis, Characterization and Antimicrobial Evolution of Six Membered Cyclic Imides

R. S. Dhivare1, S. S. Rajput*2 1Department of Chemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2Department of Chemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T The six membered cyclic imide derivatives were synthesized by reacting glutaric anhydride with different substituted aromatic amines to get 4-(N-phenylcarbamoyl) butanoic acid. These intermediates underwent ring closer with ... Read More »

Studies on the molecular interaction of Neutral Red with surfactants

Papiya Jana1, V. Padmavathy2 and Asok K. Jana2* 1Department of Chemistry, Sri Manakula Vinayagar Engineering College, Pondicherry 605 107, India 2Department of Chemistry, Kanchi Mamunivar Centre for Post-Graduate Studies, Pondicherry-605 008, India  A B S T R A C T The spectrophotometric studies of neutral red (NR) dye in an aqueous solution containing three different types of surfactants such as ... Read More »

Method Development and Validation for Simultaneous Estimation of Isoniazid and Ethambutol by using RP-HPLC in Bulk and Pharmaceutical Dosage form

Etika Madhu*, Dr. Alagar Raja. M, K.N.V Rao,David Banji Departmernt of Pharmaceutical Analysis, Nalanda College of Pharmacy, Nalgonda, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Isoniazid and Ethambutol in bulk and pharmaceutical dosage form. The separation was carried out on a [Column: Inertsil ... Read More »

To study the variations in Chemical parameters of water during the pre – monsoon and the post monsoon seasons – A case study of Upper Lake, Bhopal

Ranjana Talwar*1, Swasati Bhattacharya2, Amit Chowdhury3, Avinash Bajpai4, Suman Malik5 1Extol Faculty of Life Sciences, Bhopal, India 2,3Dept of Zoology, East Calcutta Girls College, Laketown, Kolkata 4Makhanlal Chaturvedi University, Bhopal, India 5Head of Dept. of Chemistry Sadhu Vaswani College Bhopal, India A B S T R A C T Upper Lake of Bhopal is the chief source of potable water ... Read More »

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