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Trivikram Rawat1*, I.P.Pandey2, Suman Lata Chhimwal2 1Member, American Association of Pharmaceutical Scientists, Unites States of America 2Department of Chemistry, D.A.V. (P.G.) College, Dehradun, 248001, India A B S T R A C T The aim of the present study was to investigate the various chemical components present in the volatile oil of leaves of Cymbopogon citratus and to determine its ... Read More »
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Green Synthesis of Fulgenic Acids from Stobbe Condensation Method
aYadav Hanuman Singh*, bGadegone Sunita and cPande Hemant bDepartment of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur-440009, India a,cDr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India A B S T R A C T One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to diacidswerereported. The ... Read More »
Synthesis and Spectral Studies of Novel 3-(5-mercapto-1, 3, 4-oxadiazol-2-yl)-2H-chromen-2-one Derivatives as Anticancer Agents
Chamandeep Kaur Bhinder1*, Amandeep Kaur2 1Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India 2Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India A B S T R A C T In recent years, researchers hunt for a novel anticancer agent mainly from plants. Among various phytochemicals, coumarins have attracted considerable interest in the past few years due to their ... Read More »
Synthesis, Characterisation and Biological Evaluation of Benzo [1, 4] Diazepine Derivatives linked with 7-aza Indole ring
V. Prabhakar*1, C. Divya Vani2, B. Roopa2 1Department of Chemistry, Sri Krishnadevaraya University, Ananthapuramu, Andhra Pradesh, India. 2Department of Chemistry, Sri Padmavati Women’s Degree & PG College, Tirupati, Andhra Pradesh, India. A B S T R A C T Heterocyclic compounds occur widely in nature and quite a few of these are essential to life processes. The literature on heterocyclic ... Read More »
GC-MS Studies of Crinum defixum Ker-Gawler Leaves
A. Elaiyaraja*, G. Chandramohan Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi, Thanjavur-613 503, Tamilnadu, India. A B S T R A C T The present study was carried out to identify the phytochemical present in the Crinum defixum Ker-Gawler leaves. It is an important medicinal plant worldwide trends towards the utilization of natural plant remedies has created an enormous ... Read More »
Formulation and Evaluation of Avanafil Orodispersible Tablet
Anuradha Patel*, Ajay Nair, Parixit Prajapati, Dr. Anil Jadhav Department of Pharmaceutics, Smt. B.N.B Swaminarayan Pharmacy College, Salvav, Vapi, Gujarat, India. A B S T R A C T The aim of this study is to improve the solubility and oral bioavailability of Avanafil a recently approved second generation type 5 phosphodiestrase inhibitor used for the treatment of erectile dysfunction ... Read More »
Multi-component, Catalyst free Synthesis of α-Aminonitrile by Using of Glycerol as Recyclable and Green Solvent
Amir Hossein zamania*, Saeedeh shariatib, Hamid Reza Ghaienia aMalekAshtar University of Technology, Tehran, Iran, 1465943681 bAhvaz Jundishapur University of Medical Sciences. School of Pharmacy, Ahvaz, Iran, 1579461357 A B S T R A C T We describe the use of glycerol as an efficient, safe and recyclable solvent in the one-pot reaction of aldehydes, amines, and trimethyl silylcyanide to afford ... Read More »
Formulation and Evaluation of Chlorzoxazone Mucoadhesive Tablets
Ch. Praveen Kumar, G. Padmaleela*, S. Sucharitha, K. Gnanaprakash Department of Pharmaceutics, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore-524346, Andhra Pradesh A B S T R A C T In the last two decades, mucoadhesion has shown renewed interest for prolonging the residence time of mucoadhesive dosage forms through various mucosal routes in drug delivery applications. In the present exploration ... Read More »
Structure -Activity Correlation of Thiophene-2- Sulfonic Acid and Thiophene by Rapid Chlorination Kinetics using Hydrodynamic Voltammetry
V.T. Borkar* Department of Chemistry, Nowrosjee Wadia College Research Centre, Affiliated to the Savitribai Phule Pune University, Pune, Maharashtra, India A B S T R A C T The rapid chlorination kinetics of thiophene-2-sulfonic acid by molecular chlorine in aqueous solution has been investigated employing hydrodynamic volatammetry. The specific reaction rate and energy of activation for the reaction were found ... Read More »
Synthesis, characterization and antimicrobial evaluation of novel compounds of 1-(2, 5-difluorobenzoyl)-4-(2-(4-phenyl)hydrazono)-3-(5-(4-(trifluoro methyl) phenyl) -1H-tetrazol-1-yl)-1H-pyrazo l – 5(4H)-one
M. Swarna Kumari*1, K. Sudhakar Babu1, L.K. Ravindhranath1, J. Latha3, K. Harinagamaddaih2 1,2Department of Chemistry, Sri Krishnadevaraya University, Anantapur , A.P, India. 3Department of Bio-technology, SKUCET, Sri Krishnadevaraya University, Anantapur, A.P, India. A B S T R A C T New novel derivatives of 3-chloro-6-(2,5-difluorobenzoyl)-1-(phenylamino) -8-(5-(4-(trifluoromethyl) phenyl)-1H-tetrazol-1-yl)-1,6,7-triazaspiro[3.4]oct-7-ene-2,5-dione (2a-g) were prepared by condensation of 1-(2,5-difluorobenzoyl)-4-(2-phenyl hydrazono)-3-(5-(4-(trifluoromethyl)phenyl)-1H-tetrazol-1-yl)-1H-pyrazol-5(4H)-one(1a-g). Newly synthesized compounds were characterized by ... Read More »
