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G. Varun Kumar*, V. Pavan kumar, M. Gobinath, V. Hari Baskar, Ramesh Dhani, Y. Vijitha Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A new simple accurate and suitable reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Linagliptin in ... Read More »
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Microwave Assisted Synthesis and Antimicrobial activities of 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro-2H-pyrrolo[2,3-c,5,4-c] di pyrazole
Ravindra S. Dhivare1, S. S. Rajput*2 1Department of Chemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2Department of Chemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T The novel pyrazole derivatives were synthesized by reacting substituted bis-chalcones with 4-hydroxy-3-methoxy benzaldehyde to get 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro -2H-pyrrolo [2,3-c,5,4-c] dipyrazole using solvent-free microwave method. All these derivatives were screened ... Read More »
Development and Validation of RP-HPLC Method for the Estimation of Olmesartan Medoxomil and Cilnidipine in Tablet Dossage Form
Devalam Madhu*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, N. Vamsi Krishna Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Olmesartan medoxomil and Cilnidipine in Tablet dosage form. Chromatogram was run ... Read More »
Evaluation of levels of minerals and trace elements of Cocoa (Theobroma cacao) in Côte d’Ivoire.
Dion-Laine Massiata1, Trebissou Jonhson Noel D2*, Lohoues Essis Esmel C 1, Sess E Daniel1 1Biochemistry Laboratory, Faculty of Medical Sciences, University of Félix Houphouët-Boigny, BP 582 Abidjan 22- Côte d’Ivoire. 2Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University. PO Box, 582, Abidjan 22- Côte d’Ivoire. A B S T R A C T Evaluate the levels of minerals and ... Read More »
Antidepressant Activity of Different Extracts of Nelumbo Nucifera Leaves in Laboratory Animals
Krishna Prasad D*1,2, Sriharsha SN2, Madhusudan Rao Y1, V. Naveena1 1*Vaagdevi Institute of Pharmaceutical Sciences, Bollikunta, Warangal, Telangana, India. 2Pacific College of Pharmacy, Pacific University, Udaipur, Rajasthan, India. A B S T R A C T In the present study, the anti-depressant activity of Nelumbo nucifera Gaertn. leaves (Nymphaeceae) was studied in acute model forced swimming test (FST) and tail ... Read More »
Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles
B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »
Development of Stomach Specific Floating Oral Insitu Gel of Domperidone for Children
M. Nirosha*1, S. Mumtaz Begum2, B. Hari Krishna2, V. Manideep2, G. Soujanya2, G. Venkatesh2 1Department of Pharmaceutics, OTRI, JNTUA, Ananthapuramu, A.P, India. 2Department of Pharmaceutics, SKUCOPS, SK University, Ananthapuramu, A.P, India. A B S T R A C T Domperidone, is an antiemetic drug, has been used as an add-on treatment in adults and children. To reduce the dosing frequency ... Read More »
Floating Drug Delivery System, Formulation, Evaluation, Application and Recent Advances-A Review
Navneet Kumar Verma*, P.D. Panda, Wajahat Ullah Khan, Priyanka Agrahari, Somika Singh Asst. Professor, Kailash Institute of Pharmacy and Management, GIDA, Gorakhpur, U.P, India A B S T R A C T Floating drug delivery systems (FDDS) or hydrodynamically controlled systems are low-density systems that have sufficient buoyancy to float over the gastric contents and remain buoyant in the stomach ... Read More »
Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Isoniazid and Ethambutol in Combined Tablet Dosage Form
Gampa Vijaya Kumar1*, N. Rajendra Prasad2 1Professor, Departmernt of Pharmaceutical Analysis, CVM College of Pharmacy, Velichala, Kothapally, Karimnagar, Telangana-505451 2Asst. Professor, Departmernt of Pharmaceutical Analysis, CVM College of Pharmacy, Velichala, Kothapally, Karimnagar, Telangana-505451 A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Isoniazid and Ethambutol in Tablet dosage ... Read More »
Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Lopinavir and Ritonavir in Combined Tablet Dosage form
Gampa Vijaya Kumar1*, N. Rajendra Prasad2 ... Read More »
