Wednesday , 17 July 2024

Analytical Method Development and Validation of Chloro Impurity and Methyl Ester Impurity by using RP-HPLC

Suryanarayana Gottapu*1, Hirdayesh kumar Vatsa1, B. Anitha2 1Monad Univeristy, Hapur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, Telangana, India A B S T R A C T A simple and precise RP-HPLC method was developed for the determination of Apixaban impurities like Chloro impurity and Methyl ester impurity. The chromatographic separation was achieved on an Zorbax Bonus RP ... Read More »

Analytical Method Development and Validation of Apixaban and Dehydro Impurity by Using RP-HPLC

Suryanarayana Gottapu*1, Dr. Hirdayesh kumar Vatsa1, B. Anitha2 1Department of Pharmaceutical Analysis, Monad Univeristy, Hapur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, Telangana, India A B S T R A C T A simple and precise RP-HPLC method was developed for the determination of Apixaban impurities like Acid impurity and Amino acid impurity. The chromatographic separation was achieved ... Read More »

Analytical Method Development and Validation for Apixaban by RP-HPLC

Md. Abdul Majeed*1, Dr.K.Vijaya1, B. Anitha2 1Department of Pharmaceutical Analysis, Monad Univeristys, Hapur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, Telangana, India A B S T R A C T A simple and precise RP-HPLC method was developed for the determination of Apixaban dosage form the chromatographic separation was achieved on an Zorbax Bonus RP (250 X 4.6mm) ... Read More »

Method Development and Validation of Amino Acid and Acid Impurities of Apixaban

Md. Abdul Majeed*1, Dr. K. Vijaya1, B. Anitha2 1Department of Pharmaceutical Analysis, Monad Univeristy, Hapur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, Telangana, India A B S T R A C T A simple and precise RP-HPLC method was developed for the determination of Apixaban impurities like Acid impurity and Amino acid impurity. The chromatographic separation was achieved ... Read More »

Formulation and Evaluation of Simvastatin Effervescent Floating Tablets

B. Venkateswara Reddy1*, M.Sekar2  1Department of Pharmaceutics, Santhiram College of Pharmacy, Nandyal, Kurnool-518501 2Department of Pharmaceutical Chemistry, Santhiram College of Pharmacy, Nandyal, Kurnool-518501 A B S T R A C T In the present research work gastro retentive floating matrix formulation of Simvastatin were prepared by using various hydrophilic polymers. Gas generating agent sodium bicarbonate concentration was optimized. Then formulations ... Read More »

Nanochemistry: Recent Advances and Future Perspectives: A Review

Amol S Dighe*1, Sunil A.Nirmal1, NachiketS.Dighe1, RavindraB.Laware2, SantoshB.Dighe3 1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India. 2Dept. of Quality Assurance and technique, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India. 3Departments of Pharmacology, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India. A B S T R A C T Nanoscience and nanotechnology represent ... Read More »

Various Biological Activity of 1, 3, 4-Oxadiazole Derivatives: A Review

M Somashekhar*, R B Kotnal Department of Pharmaceutical Chemistry, BLDEA’S College of Pharmacy, Vijaypur-586101. A B S T R A C T Oxadiazole a heterocyclic nucleus has attracted a wide attention for the researchers in search for the new therapeutic molecules. Among them, 1,3,4-oxadiazoles have exhibited a wide range of biological properties. The first mono-substituted 1,3,4-oxadiazoles were reported in 1955 ... Read More »

Design and In-Vitro Characterization of ORO Dispersible Tablets of Azithromycin

H. Padmalatha*  HOD, Pharmaceutical analysis and QA, Gyana Jyothi College of Pharmacy, Boduppal, Hyderabad. A B S T R A C T The goal of this project is to formulate Oro-dispersible tablet of Azithromycin that is intended to disintegrate rapidly into the oral cavity and form a stabilized dispersion. A direct compression method was failed to formulate dispersible tablet of ... Read More »

Evaluation of Antihyperlipidemic Activity on Ethanolic extract of Caesalpinia sappan L in hyperlipidemic rats.

P. Naresh Babu1 SK. Karimulla1, Anupam Kanti Bag1, M.Gobinath2, B. Bharathi*1 1Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. 2Principal and Professor, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore, A.P, India. A B S T R A C T The anti-hyperlipidemic effect of ethanolic extract of heart wood of caesalpinia sappan L (CSP) was tested ... Read More »

Antifertility activity of Polyalthia suberosa in male and female wistar albino rats

Sk. Karimulla, Challa Sujitha*, M. Gobinath, B. Bharathi Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. A B S T R A C T To evaluate the potential spermatotoxic effect of ethanolic extract of Polyalthia suberosa in male albino rats. Ethnolic extract of Polyalthia suberosa  were given by gavage to rats in the in vivo ... Read More »

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