Tuesday , 16 July 2024

Design, Synthesis and Biological Evaluation of New Rennin Inhibitors

S.P. Likitha Rao*1, Anil Middah1, Neeraj Tandan2 1Department of Pharmaceutics,OPJS University, Rajasthan, India 2SARC (Scientific and Applied Research Centre) – Meerut A B S T R A C T Hypertension is a major risk factor for cardiovascular diseases such as stroke, myocardial infarction, and heart failure, the leading causes of death in the western world. Inhibitors of rennin –angiotensin system ... Read More »

Retrospective study pattern of Drug utilization and Antihypertensive Management in Pregnancy

Sk. Meharunnisa*, B. Kumar, M. Gobinath Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. A B S T R A C T Pregnancy is a state in which a woman carries a fertilized egg inside her body. Hypertensive disorders affect 10-22% of pregnancies in major population.  Pre-Eclampsia is thought to affect 5-8% of pregnancies. ... Read More »

Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Telmisartin and Atorvastain in Tablet Dossage Form

Y. Vijitha*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, G. Varun Kumar Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. A B S T R A C T A simple, sensitive and reproducible reverse-phase high performance liquid chromatographic (RP- HPLC) method has been developed for simultaneous quantitative estimation of Atorvastatin calcium ... Read More »

Formulation and Evaluation of Bilayer Tablets of Pioglitazone and Glibenclamide

Jeripiti Usha, Venugopalaiah P*, Gnanaprakash K, Gobinath M Department of Pharmaceutics, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore-524346, A.P, India A B S T R A C T An attempt was made to formulate the bilayer dosages form containing Pioglitazone HCl as immediate release layer and Glibenclamide as sustained release layer, for the management of Type II Diabetes Mellitus. The ... Read More »

Formulation and Evaluation of Mucoadhesive Tablets of Metoprolol Tartarate

B. Venkateswara Reddy1*, M.Sekar2  1Department of Pharmaceutics, Santhiram College of Pharmacy, Nandyal, Kurnool Dt-518501 2Department of Pharmaceutical Chemistry, Santhiram College of Pharmacy, Nandyal, Kurnool Dt-518501 A B S T R A C T The aim of the present study was to design mucoadhesive tablets of Metoprolol Tartarate to release the drug unidirectionally in buccal cavity in order to avoid first-pass ... Read More »

Formulation and Evaluation of Fenofibrate SR Capsules

B. Ramya Krishna1, Gampa Vijaya Kumar*2, P. Sridhar3, K. Someshwar4 1CVM college of Pharmacy, Karimnagar, Telangana, India 2Professor & Principal, CVM college of Pharmacy, Karimnagar, Telangana, India 3Assistant professor, CVM college of Pharmacy, Karimnagar, Telangana, India 4Managers, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad, Telangana, India A B S T R A C T Fenofibrate is a ... Read More »

Formulation and In-Vitro Evaluation of Colon Targeting Drug Delivery System of Mesalamine tablets

B. Ramesh1, Gampa Vijaya Kumar*2, P. Sridhar3, K. Someshwar4 1CVM College of Pharmacy, Karimnagar, Telangana, India 2Professor & Principal, CVM college of Pharmacy, Karimnagar, Telangana, India 3Assistant professor, CVM college of Pharmacy, Karimnagar, Telangana, India 4Managers, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad, Telangana, India A B S T R A C T In the present research ... Read More »

Memory enhancing activity of Cordia Subcordata Lam.

C. Madhavi Latha*1,2, K. Bhaskar Reddy3 1Research Scholar, Pacific University of Higher Education and Research University, Udaipur, Rajastan, India. 2Department of Pharmacology, Jagan’s College of Pharmacy, Nellore, Andhra Pradesh, India. 3Department of Pharmaceutics, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor, India. A B S T R A C T The present study was undertaken to investigate the effects of ... Read More »

Evaluation of Antidiabetic of Methanolic Leaf Extract of Bombax Ceiba on Streptozotocin Induced Diabetic Rats

Khan Majid Shabbir1,I. Sarath Chandiran*2, P.D. Chaudhari3   1Research Scholar, Prist Univesity, Vallam, Thanjavur, Tamilnadu, India 2Professor, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore-524346, Andhra Pradesh, India 3Principal, Modern College of Pharmacy, Nigdi, Pune-44, Maharashtra, India. A B S T R A C T The present study was aimed to investigate the antidiabetic activity of methanolic extract of leaf of Bombax ... Read More »

Anti-inflammatory activity of flavonoids from medicinal plants against hepatitis B vaccine antigen on human peripheral blood mononuclear cells

Amit Gupta* and Sushama R Chaphalkar Department of Immunology, Vidya Pratishthan’s School of Biotechnology, Baramati, District Pune, Maharashtra India A B S T R A C T The objective of our study is to investigate the anti-inflammatory activity of the variable doses of flavonoids (6.25 – 25 mg) extracted from the leaves of Syzygium cumini, Acacia catechu and Azadirachta indica ... Read More »

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