Wednesday , 17 July 2024

Pharmacokinetic Drug Interaction of Quetiapine and Pioglitazone in Animal Models

Bhupalam Pradeepkumar 1*, Y. Padmanabha Reddy 2, N. Devanna3 1Department of Pharmacology, Center for Pharmaceutical Research, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu-515721, Andhrapardesh, India. 2 Principal, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu – 515721, A.P, India. 3 Principal, JNTUA College of Engineering, Kalikiri – 515234, Andhra Pardesh, India. A B S T R A C T ... Read More »

Influence of Olanzapine on the Pharmacodynamics and Pharmacokinetics of Pioglitazone in Animal Models

Bhupalam Pradeepkumar1*, Y. Padmanabha Reddy 2,N. Devanna3 1Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu-515721, Andhra Pardesh, India. 2Principal, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu-515721, A.P, India. 3Principal, JNTUA College of Engineering, Kalikiri – 515234, Andhra Pradesh, India. A B S T R A C T The present study was performed to investigate the effect ... Read More »

Preventive Effect of Premna Latifolia against High Fructose Diet Induced Insulin Resistance, Hyperlipidemia and Obesity in Male Wister Rats

Gampa Vijaya Kumar*1, K. Ramprasad2 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Keesara,Rangareddy, Telangana, India. 2Department of Pharmacology, Sree Chaitanya Institute of Pharmaceutical Sciences, L.M.D Colony, Thimmapur, Karimnagar, Telangana, India. A B S T R A C T The aim of this study was to investigate ant diabetic effect of premna latifolia on the ... Read More »

Popular Polymers used for Fabricating fast Dissolving Tablets to treat Arthritis: A Technical Review

Yaswanth M, Hindustan Abdul Ahad*, Pruthvimani N, Sashi Kumar, Vanajakshi M, Jacqueline PRB Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India A B S T R A C T A wide range of drugs have been studied in the form of fast dissolving tablets to treat arthritis. Many polymers were tried in single, combination of two and more for fabricating ... Read More »

Formulation and evaluation of fast dissolving Tablets of nizatidine

G. Archana*1, Hindustan Abdul Ahad2, P. Siva Kumar1 1Department of Pharmaceutics, Gokul Krishna College of Pharmacy, Sullurpet, Nellore, Andhra Pradesh, India 2Department of Pharmaceutics, Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India A B S T R A C T Nizatidine is a H2 receptor antagonist used to treat gastric and duodenal ulcers and gastroesophogeal reflux disease. Fast dissolving tablets ... Read More »

Synthesis, Characterisation and Biological Evaluation of Novel BIS 1,3,4-Thiadiazole ring containing Indole and pyridine Moieties

V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A P, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu – 515003 (A.P) India A B S T R A C T The article is aimed to synthesize, characterize and screening the biological activity of 2-(5-(1H-indole-2-yl)-1, 3, ... Read More »

Rosuvastatin Calcium Immediate Release Tablets

T. Satyanarayana*1, K. Someshwar2 1Department of Pharmaceutics, Browns College of Pharmacy, Khammam, Telangana, India 2Managers, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad, Telangana, India A B S T R A C T In the present research Rosuvastatin calcium immediate release tablets were formulated and evaluated. Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting ... Read More »

Spectrophotometric Determination of Moxifloxacin Hydrochloride using Palladium (Pd-II) ions in micellar medium

Madhuri.D1*, Chandrasekhar K.B2, Devanna N3, Somasekhar G4 1Department of Pharmaceutical Analysis, Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, A. P, India 2Director & Professor, OTPRI-JNTUA, Anantapur, A.P, India-515002 3Professor, Department of Chemistry, JNT University, Anantapur A.P, India-515002 4Department of Pharmaceutical Chemistry, Safa College of Pharmacy. Kurnool, A.P, India A B S T R A C T A simple ,sensitive ... Read More »

Efficacy of PARP1 inhibitor nutlin3a on liver injury induced by Ischemia-reperfusion

Daisuke Kawahara1, Kosho Yamanouchi 1, Naoyuki Okita2, Tamotsu Kuroki1, Yoshikazu Higami2 and Susumu Eguchi1 1Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan 2Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-0022, Japan A B S T R A C T Nutlin 3a was known ... Read More »

Synthesis and Characterization of Zn-Al-Cl of Hydrotalcites and their Application in Four Component Synthesis of 4H-Pyrano[2,3C] Pyrazoles

Jugraj Jatav*, Ruchi Gupta, Santosh Kumar Bhardwaj Department of Chemistry, Jiwaji University, 474011 Gwalior, M.P. India A B S T R A C T Zn/Al hydrotalcite acts as an efficient heterogeneous basic catalyst for the synthesis of 4H-pyrano[2,3-c] pyrazoles via a multi-component reaction of  hydrazine hydrate, ethyl acetoacetate, aldehydes, and malononitrile in ethanol at ambient temperature. The hydrotalcite catalyst was ... Read More »

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