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Dr. Gampa Vijaya Kumar*1, Dr. Nagaraju2, M. Kulkarni2, B. Shiva kumar2, S. Raju2 1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The present research work is involved with the evaluation of Acorus ... Read More »
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Evaluation of Antioxidant Activity for Salvia Officinalis Using In-Vivo and In-Vitro Methods
Dr. Gampa Vijaya Kumar*1, Dr. Y. Sridhar2, B. Prathyusha3, S. Raju4 1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2,3,4KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T On the basis of our findings, it may be worthy to suggest that ... Read More »
Pharmacovigilance Methods: A Review
Musali Muni kumari*, Saritha Chandra, Dr. P. Venkatesh Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukur (M), SPSR Nellore-524348. A B S T R A C T Pharmacovigilance is “defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, principally long term and short term adverse effects of medicines. It is an important and ... Read More »
Medicinal Chemistry of Tyrosine Kinase Inhibitor Drug: A Review
Amol S Dighe*1, Sagar D. Magar1, Nachiket S. Dighe2 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India A B S T R A C T Tyrosine kinases are a part of many cell functions, including cell signaling, growth, and division. These enzymes may be too active or found at high levels in some types of ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril and Hydrochlorothiazide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Jyothi Keerthi*, G. Devika Subramaniyan Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A Reverse Phase High Performance Liquid Chromatography method was developed for the determination of Enalapril and Hydrochlorothiazide in bulk and Pharmaceutical dosage form. The separation was achieved on an Inertsil ODS (250×4.6mm),5µm column by using a mixture of Phosphate ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Raltegravir and Lamivudine by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Parsa Sivarama Krishna*, G. Devika Subramaniyan Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana A B S T R A C T A simple, accurate, precise method was developed for the simultaneous estimation of the Raltegravir and Lamivudine in Tablet dosage form. Chromatogram was run through Inertsil ODS 3V(250×4.6mm)5µm column by using a mixture of Phosphate buffer and acetonitrile in a ... Read More »
Formulation Development and In-vitro Evaluation of Bosentan Gastroretentive Drug Delivery System
Seelam Manasa*, Y. Krishna Reddy Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana A B S T R A C T The present investigation of the development of floating tablets are used in the treatment of high blood pressure in the lungs (pulmonary arterial hypertension). The Bosentan floating tablets were prepared by direct compression method. The evaluation of Precompression Blend Flow ... Read More »
N-[4-[Benzyloxy] benzyl]-benzenemethaneamines with High Biological Activity against Intracellular Trypanosoma cruzi and Leishmania infantum Amastigotes
Gabrielle Frizzo Souza1, Simon Bernhard Cämmerer1*, Caio Haddad Franco2, Laura Maria Alcantara2, Carolina Borsoi Moraes2, Lucio Holanda Freitas-Junior2* 1Instituto de Química, Universidade Estadual de Campinas, Rua Monteiro Lobato S/N, Cidade Universitaria Zeferino Vaz, Barão Geraldo, CP 6154, CEP 13083-970, Campinas, São Paulo, Brasil. 2Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Rua Giuseppe Maximo ... Read More »
Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms
Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India. A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »
Antioxidant and Antimicrobial Activity of Grape Skin
Ms. Sneha V & Dr. V. Judia Harriet Sumathy Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai – 600 006. A B S T R A C T Grape (Vitis vinifera) skins and seeds are considered to be rich sources of poly-phenolic compounds.Using the sap of grapevines, European folk healers sought to cure skin and eye diseases. Other ... Read More »
