Wednesday , 17 July 2024

Synthesis, spectral, biological applications on cobalt(III) dithiocarbamate complexes and their solvothermal decomposition to nano cobalt(II) sulphide

A.S. Sonia*, R. Baskaran Department of Chemistry, Annamalai University, Annamalai Nagar, T.N, India-608 002. A B S T R A C T Octahedral diamagnetic [Co(eedtc)3] (1), [Co(medtc)3] (2), [Co(bhpdtc)3] (3) and [Co(cedtc)3](4) (where eedtc = N-ethyl-N-(2-hydroxyethyl) dithiocarbamate anion, medtc = N-methyl-N-(2-hydroxyethyl) dithiocarbamate anion, bhpdtc =N-benzhydryl piperazine dithiocarbamate anion and cedtc = bis(2-cyanoethylamine)  dithiocarbamate anion) have been prepared. The synthesized complexes ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril and Hydrochlorothiazide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Jyothi Keerthi*, G. Devika Subramaniyan, Ramesh Petchi, Rajendran Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A Reverse Phase High Performance Liquid Chromatography method was developed for the determination of Enalapril and Hydrochlorothiazide in bulk and Pharmaceutical dosage form. The separation was achieved on an Inertsil ODS (250×4.6mm),5µm column by using a ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Raltegravir and Lamivudine by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Parsa Sivarama Krishna*, G. Devika Subramaniyan, Ramesh Petchi, Rajendran Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana A B S T R A C T A simple, accurate, precise method was developed for the simultaneous estimation of the Raltegravir and Lamivudine in Tablet dosage form. Chromatogram was run through Inertsil ODS 3V(250×4.6mm)5µm column by using a mixture of Phosphate buffer and ... Read More »

Formulation Development and In-vitro Evaluation of Bosentan Gastroretentive Drug Delivery System

Seelam Manasa*, Y. Krishna Reddy Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana A B S T R A C T The present investigation of the development of floating tablets are used in the treatment of high blood pressure in the lungs (pulmonary arterial hypertension). The Bosentan floating tablets were prepared by direct compression method. The evaluation of Precompression Blend Flow ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

N-[4-[Benzyloxy] benzyl]-benzenemethaneamines with High Biological Activity against Intracellular Trypanosoma cruzi and Leishmania infantum Amastigotes

Gabrielle Frizzo Souza1, Simon Bernhard Cämmerer1*, Caio Haddad Franco2,  Laura Maria Alcantara2, Carolina Borsoi Moraes2, Lucio Holanda Freitas Junior2* 1Instituto de Química, Universidade Estadual de Campinas, Rua Monteiro Lobato S/N, Cidade Universitaria Zeferino Vaz, Barão Geraldo, CP 6154, CEP 13083-970, Campinas, São Paulo, Brasil. 2Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Rua Giuseppe ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms

Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »

Antioxidant and Antimicrobial Activity of Grape Skin

Ms. Sneha V & Dr. V. Judia Harriet Sumathy Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai – 600 006. A B S T R A C T Grape (Vitis vinifera) skins and seeds are considered to be rich sources of poly-phenolic compounds.Using the sap of grapevines, European folk healers sought to cure skin and eye diseases. Other ... Read More »

Antioxidant Activity of Lycopene from Papaya

Ms. Harini R & Dr. V. Judia Harriet Sumathy Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai – 600 006. A B S T R A C T A modern life style keeps people away from healthy diet. For healthy dietary habits one should increase the consumption of food products which are helpful in the prevention of illness. ... Read More »

Pharmacovigilance Methods: A Review

Musali Muni kumari*, Saritha Chandra, Dr. P. Venkatesh Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukur (M), SPSR Nellore-524348. A B S T R A C T Pharmacovigilance is “defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, principally long term and short term adverse effects of medicines. It is an important and ... Read More »

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