Sunday , 30 June 2024

Preclinical Safety, toxicology studies of Wamup gel- A novel Formulation with L-Arginine on Wistar Rats

U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T WAMUP is an aqueous based gel formulation containing 5% L-Arginine for topical application for both males & females. L-arginine in WANUP GEL releases nitric oxide (NO) through nitric ... Read More »

Method Development and Validation of Artemether and Lumifantrine by RP-HPLC

Farhana Shaheen*, Rubina Kauser, Salma Begum, Airaj Mahajabeen, Md Fasiuddin MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Introduction Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the immobilized ... Read More »

Design and Characterisation of Rifamiximin Multiparticulate Colon Targeted Drug Delivery

Dr. Hareesh Dara*, D. Siva dinesh, Dr. Thatipelli Ravichander The St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana A B S T R A C T Aim of present work was design and develop consistent and optimized formulations of Rifaximin multiparticulate targeted drug delivery to colon with the following objectives.,explore multiparticulate CDDS to achieve localized effect and evaluate the pH- ... Read More »

Design and Characterisation of Aceclofenac Multiparticulate Colon Targeted Drug Delivery

Dr. Hareesh Dara*, D. Siva dinesh, Dr. Thatipelli Ravichander The St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana A B S T R A C T Present work was design and develop sconsistent and optimized formulations of aceclofenac multiparticulate targeted drug delivery to colon with the following objectives. The first purpose of the study was developing multiparticulate cdds by means ... Read More »

Pharmacological Screening and Phytochemical Evaluation of Anti-Diabetic Activity of Asparagasus Racemosus Leaves in Normal and Alloxan Induced Diabetic Rats

Dr. Hareesh Dara*, D. Siva dinesh, Dr. Thatipelli Ravichander The St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana A B S T R A C T Diabetes mellitus is a most common endocrine disorder, affecting more than 300 million people worldwide, we studied the anti-diabetic potential of leaves of A.Racemosus. The acute oral toxicity studies of the extracts revealed no ... Read More »

Evaluation of antidepressant activity of hypericum perforatum using experimental models of depression in rats

Dr. Hareesh Dara*, D. Siva dinesh, Dr. Thatipelli Ravichander The St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana A B S T R A C T Depression constitutes the second-most common chronic condition in clinical practice, exceeded only by hypertension. Despite recent progress achieved in the development of clinically relevant antidepressant drugs in recent years, the currently available antidepressant therapy ... Read More »

Development and Validation of Novel RP-HPLC Method for Simultaneous Estimation of Cobicistat and Atazanavir in Synthetic Mixture

Srinivas Ganta*, Vidyadhara S Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur – 522018, Andhra Pradesh, India. A B S T R A C T A simple accurate and selective Rp-HPLC Assay method was developed for the simultaneous estimation of three drugs Cobicistat (COB) and Atazanavir (ATA) in their tablet formulation. Two drugs were separated on Xterra C18 (5μm, 15cm ... Read More »

Formulation and Evaluation of Colon Targetted Drug Delivery System of Theophylline for the Treatment of Nocturnal Asthma

Y. Swetha, Venugopalaiah .P*, D. Sravanthi Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore, Andhra Pradesh, India A B S T R A C T The site specific release in the colon affects a time delay between administration and onset of action, which can be useful for diseases with various degrees of severity, such as asthma and arthritis. In the present ... Read More »

Formulation Development and optimization of Lyophilized product of an Anti Ulcer Drug

GY. Srawan kumar, V Deva Prasad, Raveendra, Harish K, Ann Jose, Reny Jose, Durga, Rachel mathai, Kempe gowda. Hindu College of Pharmacy, Guntur, Andhra Pradesh, India. Strides Arcolab Limited, Bangalore-560076, India Abstract The aim of present research work was to formulate an intravenous injection of Omeprazole sodium. Omeprazole drug is very slightly soluble in water. Hence in-situ conversion of Omeprazole ... Read More »

A Review on Transdermal Patches

Vadlamudi Manohar, R.V.S. Mounica, Saritha Chandra*, Dr. P. Venkatesh Jagan’s college of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India A B S T R A C T Transdermal drug delivery (TDDS) is regarding application of drug on the skin surface so that it can permeate through the skin & reaches the systemic circulation at sufficient concentration to ensure therapeutic ... Read More »

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