Saturday , 29 June 2024

Matrix Diffusion Controlled Release Tablets of Repaglinide-Formulation and In-vitro Evaluation

P. Suresh1*, U. Venkatesh1, P. Anwar Basha1, B. Yogesh, G. Sravan reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T The purpose of present reaserch work was to prepare and evaluate the controlled release tablets of Repaglinide. Direct compression method was used to prepare the tablets ... Read More »

Preclinical safety, toxicology and efficacy studies of Recombinant Exendin-4 (Antidaibetic peptide) on wistar rats

U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T Recombinant Exendin-4 is a 39 amino acid peptide which exhibits sequence identity over 30 amino acids with mammalian glucagon like peptide-1 (GLP-1) and shares many of the gluco-regulatory ... Read More »

Thiopurine methyl transferase enzyme activity-relationship to the dose and adverse effects of 6-mercaptopurine in children with acute lymphoblastic leukemia

Osama A.E. Ali*, Nabeel A.J.Ali1, Janan G. Hassan2 1MBChB, PhD, Department of Pharmacology, College of Medicine, University of Basrah, Basrah, Iraq 2MBChB,FICMS, Department of Pediatrics, College of Medicine, University of Basrah, Basrah, Iraq A B S T R A C T Background: There are genetic variations in the activity of the enzyme thiopurine methyl transferase (TPMT) which lead to differences ... Read More »

Antidermatophytic activity of alkaloid and saponin extracts from Cnidoscolus aconitifolius.

Basil Ita1*, Samuel Eduok2 1Department of Chemistry, University of Uyo, Uyo, Akwa Ibom State, Nigeria. 2Department of Microbiology, University of Uyo, Uyo, Akwa Ibom State, Nigeria. A B S T R A C T The antidermatophytic activity of saponin and alkaloid extracts from organs of Cnidoscolus aconitifolius against Trichophyton rubrum, Microsporum gypseum, Epidermophyton floccosum and Trichophyton interdigitale was studied by ... Read More »

Occurrence of ESBL-producing Escherichia coli and Klebsiella pneumoniae in urinary tract infection (UTI) patients

Afiukwa Ngozi, Iroha Ifeanyichukwu, Nwuzo Agabus, Ejikeugwu Chika*, Nwakaeze Emmanuel, Ukpai Ekenem, Anthonia Orji Department of Applied Microbiology, Faculty of Sciences, Ebonyi State University, Abakaliki, P.M.B 053, Ebonyi State, Nigeria A B S T R A C T A urinary tract infection (UTI) is an infection in any part of the urinary tract system that includes infections of the kidneys, ... Read More »

Neuroprotective Effect of Walsura Piscidia Implications for Dementia of Alzheimer’s type using Female Albino Wistar Rats

P. Indiramma, B. Kumar* Department of Pharmacology, Ratnam institute of Pharmacy, Pidathapolur, Muthukur, Nellore A B S T R A C T The present study was to evaluate the Anti-dementic effect of walsura piscidia on scopolamine induced female albino wistar rats. Animals were grouped into normal, control, standard, test1 and test2.Except the normal group all the other groups received scopolamine ... Read More »

The challenging larvicidal activity of Ocimum sanctum

Pragati Khare*1, 2Kamal Kishore, 1Pranit Saraswat, 1Ritesh Kumar Tiwari and 3 Noopur Khare 1Department of Pharmacy, Shri Ram Murti Smarak (C.E.T), Bareilly, U.P, India. 2Department of Pharmacy, M.J.P. Rohilkhand University, Bareilly, U.P, India. 3Institute of Engineering and Technology, Department of Biotechnology, Lucknow, U.P, India. A B S T R A C T Mosquitoes are the main vectors that are responsible ... Read More »

Formulation and Evaluation of Ziprasidone Microspheres by Sovlent Evaporation Method

Kodur Sumathi, Penabaka Venugopalaiah*, Yerikala Ramesh Department of Pharmaceutics, Ratanam Institute of Pharmacy, Nellore -524 346, Andhra Pradesh, India A B S T R A C T The objective of the present study was formulation and evaluation of Ziprasidone microspheres by using solvent evaporation technique. Ziprasidone is loaded with ethyl cellulose & HPMC 15 microspheres and it was prepared by ... Read More »

Anti-inflammatory Activity of Ethanolic and Aqueous extracts of Toxocarpus beddomei Gamble

J. Karthi*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T In this study anti-inflammatory activity of ethanolic and aqueous extracts of Toxocarpus beddomei Gamble belonging to family apocynaceae were studied in. Preliminary phytochemical screening revealed the presence of ... Read More »

A Retrospective Study on Maternal Factors Low Birth Weight in Rural Parts of Nellore and Kurnool District, Andhra Pradesh

B. Kumar*, G. Indumathi, Yitzhak Department of Pharmacy Practice, Ratanam Institute of Pharmacy, Nellore -524 346, Andhra Pradesh, India A B S T R A C T Today’s children are tomorrow’s citizens of a country. Thus, the normal health and growth of children plays an important role in the prosperity of a country. Number of factors like maternal, socio environmental ... Read More »

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