Green Synthesis of Fulgenic Acids via Aryl Aldehydes and Ketones from Stobbe Condensation Method

^aYadav Hanuman Singh, ^bGadegone Sunita and ^cPande Hemant
^bDepartment of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur 440009, India
^a,cDr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India

A B S T R A C T
One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to diacids were reported. The Stobbe condensation of various aromatic aldehydes or ketones with dimethyl succinate gives different types of diacids [2a, (2Z,3Z)-2-3-bis(4-chlorophenyl) (phenyl) (methylene) succinic acid)], [2b,(2Z,3Z)-2-(4-chlorophenyl) (phenyl) (methylene)-3-(1-phenylethylidene) succinic acid], [2c, (2Z,3E)-2-3-bis(furan-2-ylmethylene) succinic acid)]through green approach. The improved yields of Fulgenic acid were observed by the green approach method as compared with other classical methods employed so far. 
Keywords: Green synthesis, Stobbe condensation, aryl aldehydes & ketones and their products.