Formulation and Evaluation of Controlled Release Matrix Tablets of Ketoprofen

Sukanya V^*, Naresh G, Hindustan Abdul Ahad, Gangadhar D 
PG Department of Pharmaceutics, Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India
APOTHEKE-2014, 8 Nov 2014, Organized by Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India

Abstract
The Present exploration work was planned to prepare matrix controlled discharge tablets of ketoprofen with Ketoprofen-β-cyclodextrin complex. Different formulations of ketoprofen-β-Cyclodextrins complexes were readied and the Polymers were examined for its practically as a network framing property to control the ketoprofen discharge from the dose structure. The formed tablets were assessed for pre-compression and post compression parameters which were discovered agreeable inside the points of confinement. The swelling conduct and discharge rate energy were contemplated. The in vitro dissolution study demonstrated that the ketoprofen-β-Cyclodextrins mixtures can be utilized as a lattice shaping polymers for making controlled discharge grid tablets.
Keywords: Ketoprofen, β-Cyclodextrins, Matrix tablets, Controlled release