Determination of anti-antimicrobial activity of vitis vinifera peels and seeds extracts

Bhimana Sasidhar¹, Dr. K. Harinadha Baba¹, Dasaradhan Kavitha², Edara Neeharika², Nutheti Lakshmi priya², Talla Mahitha², Venumbaka Charitha^2
1Department of Pharmaceutical Biotechnology, Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh-524002, India.
²B. Pharmacy IV^th year, Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh-524002, India.

A B S T R A C T
Vitis vinifera is rich in phenolic compounds. This fruit’s seed and peel extractions have secondary metabolites, like poly phenols and mixture of oligomeric, polymeric flavon-3-ols and monomers like gallic acid, (+)-catechin, epicatechin, dimeric procyanidin, proanthocyanidins, myricetin, quercetin, kaempferol, trans-resveratrol. These bioactive phenolic compounds possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This article carried out determination of anti-microbial activity of vitis vinifera peel and seed extractions by using vinegar and aqueous solvents. These vinegar and aqueous extractions had shown anti-microbial activity against gram-negative bacteria Escherichia coli, gram-positive bacteria Staphylococcus aureus and anti-fungal activity against black mould Aspergillus niger. The zones of Inhibition of peel and seed extraction were observed and recorded for respective microbes. It is concluded that Staphylococcus aureus, Escherichia. Coli, Aspergillus. Niger had shown high extent of zones of inhibition with vinegar thanaqueous extraction.
Keywords: Vitis vinifera, vinegar extracts, aqueous extracts, phenolic compounds, poly phenolics, antibacterial activity, anti-fungal activity