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Category Archives: Pharmaceutical Sciences and research inventions

Formulation and Evaluation of Sustained Release Tablets of Buclizine Hydrochloride

Aukula Monica, Venugopalaiah P*, K. Gnana Prakash, M. Gobinath, Masaram Saritha Department of Pharmaceutics, Ratnam Institute of Pharmacy, SPSR Nellore, Andhra Pradesh, India-524346 A B S T R A C T Sustained release, sustained action, controlled release, extended action, timed release, depot and repository dosage forms are terms used to identify drug therapy systems that are designed to achieve a ... Read More »

Development and Evaluation of Carvedilol Oral Disintegrating Tablet by Solid Dispersion Technique

Balachandrudu*, Somasekhar.G, Nazemoon.R, Raziya SMD. Department of Pharmaceutics, Safa College of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T Carvedilol is a poorly water soluble oral antihypertensive agent. An attempt has been made to develop fast dissolving the tablet of carvedilol by direct compression and solid dispersion technique the solid dispersion of carvedilol with peg-4000(1:4 ... Read More »

Bioequivalence and Pharmacokinetic Comparison between Extended Release Capsules of Carvedilol Phosphate 40mg: An Open Label, Balanced, Randomized-Sequence, Single-Dose, Two-Period Crossover Study in Healthy Male Volunteers

I. Sarath Chandiran1*, Raghunadha Reddy Seelam2, Seelam Sai Satyanaraya Reddy3, Ravindra Reddy S3 1Professor, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore-524346, Andhra Pradesh, India 2Department of Pharmaceutical Science, School of Pharmacy, University of Maryland, Pine Street, Baltimore, Maryland 21201, USA. 3Vardhaman College of Engineering, Hyderabad, Telangana, India. A B S T R A C T This present bioequivalence study was designed to ... Read More »

Patient Reported Adverse Outcomes on Treatment of Type-2 Diabetes Mellitus and Co-Morbidities in South India

Y. Siva Shankar Reddy*1, B Kumar1, Umesh Kamarthi2, M. Gobinath1 1Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Nellore. 2Clinical Pharmacist, BGS Global Hospitals, Kengeri, Bangalore, Karnataka, India, Pin–524348 A B S T R A C T To evaluate patient reported adverse outcomes in type 2 diabetes mellitus with or without co-morbidities in South India. Mainly to contact the study ... Read More »

Development and Characterization: Proniosomes of Ketoconazole for the Management of Candidiasis

Akanksha Jethmal*1, Amit K Agrawal2, Archana Tiwari2 1Department of Pharmaceutics, Vedica College of B.Pharmacy, Bhopal, M.P, India 2Department of Pharmaceutics, Patel College of Pharmacy, Bhopal, M.P, India A B S T R A C T The aim of present study was to prepare proniosomal gel for the topical drug delivery. Ketoconazole was used as proniosomal gel with sorbitol by using ... Read More »

Bio Activity Guided Separation of Acetyl cholinesterase Inhibitor from Nardostachys jatamansi

K.L. Vegad*1, N.S. Kanaki 1, M.N. Zaveri 1, E.D. Patel2 1Department of Pharmacognosy, K.B. Institute of Pharmaceutical Education and Research Centre, Gandhinagar, Gujarat, India 2Department of Pharmacology, Sharda school of pharmacy, Gujarat, India A B S T R A C T Acetyl cholinesterase (AchE) inhibitors are currently still the best available pharmacotherapy for the treatment of various neurological disorders such as ... Read More »

Evaluation of Antipathogenic Effect of Datura Metal Linn. Leaf Extract on Enterobacter Species

Sk. Salma*, Ch. Lalitha, K. Venkatarameshwar, S. Jagadeesh Babu, M. Vijitha Narayana Pharmacy College, Chintareddypalem, Nellore-524002, Andhra Pradesh, India A B S T R A C T Plants have been used as traditional medicine since time immemorial to control bacterial, viral and fungal disease. Because of the growing bacterial resistance against commercial standard and reserve antibiotics, the search for new ... Read More »

Formulation and Evaluation of Prosopis cineraria (Linn.) Druce Phospholoipid Complex

Formulation and Evaluation of Prosopis cineraria (Linn.) Druce Phospholoipid Complex Sangeeta Asija*1, G. Jeyabalan1, Anil Ahuja2, Rajesh Asija3 1Sunrise University, Alwar, Rajasthan, India 2Rajasthan College of pharmacy, Jaipur, Rajasthan, India 3Maharishi Arvind Institute of Pharmacy, Jaipur, Rajasthan, India A B S T R A C T A novel formulation of Prosopis cineraria extract in combination with the phospholipids was developed ... Read More »

Formulation and Evaluation of Cinnarizine Bilayered Tablets

Ch. Praveen Kumar, D. Mamatha*, K. Gnana Prakash, M. Gobinath  Department of Pharmaceutics, Ratnam Institute of Pharmacy, Pidthapolur(V), Muthkur(M), Nellore-524346, A.P, India A B S T R A C T In the present research work an attempt was made to prepare cinnarizine bilayered tablets, in which the drug is classified as a selective agonist of T-type voltage-operated calcium ion channels, ... Read More »

Formulation and Evaluation of ORO-Dispersible Tablets of Pantoprazole Sodium Using Direct Compression Technique

Masaram Saritha, Venugopalaiah P*, K. Gnana Prakash, M. Gobinath, Aukula Monica Department of Pharmaceutics, Ratnam Institute of Pharmacy, SPSR Nellore, Andhra Pradesh, India-524346 A B S T R A C T Among the different routes of administration , oral route of administration continues to be most preferred route due to various advantages including ease of administration, avoidance of pain, versatility ... Read More »

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