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Category Archives: Pharmaceutical Sciences and research inventions

Insulin Secretagogue Effect of Bombax Ceiba on Glucose Induced Insulin Release from Rat Pancreatic Islets

Khan Majid Shabbir1, I. Sarath Chandiran*2, P.D. Chaudhari3 1Research Scholar, Prist Univesity, Vallam, Thanjavur, Tamilnadu, India 2Professor, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore-524346, Andhra Pradesh, India 3Principal, Modern College of Pharmacy, Nigdi, Pune-44, Maharashtra, India. A B S T R A C T In the present study, the effect of methanolic leaf extract of Bombax ceiba (MEBC) was studied ... Read More »

Mucoadhesive Microspheres – A Review

Sandeep Kumar*, Vinod, Rakesh Kumar Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak – 124001, India A B S T R A C T The current article focuses on the principles of mucoadhesive drug delivery systems based on adhesion to biological surfaces. Microspheres constitute a major part of novel drug delivery system because of their small size and other efficient ... Read More »

Wheat Grass as Green blood therapy: A Review

Kiran B. Kotade*1, Swati V. Wagh1, Vijay D. Wagh2 1Department of Pharmacology, P.R.E.S.’s, College of Pharmacy (For Women), Chincholi, Nashik-422 103. 2Department of Pharmaceutics, P.R.E.S.’s, College of Pharmacy (For Women), Chincholi, Nashik-422 103 A B S T R A C T Juice of wheat grass is termed as green blood. Wheatgrass is a variety of grass that is used like ... Read More »

Hepatoprotective Activity of Ethanolic Extract of Rhizomes of Curculigo Orchioides

D. Bargavi*, Anupam Kanti Bag, Sk. Karimulla, M. Gobinath Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. A B S T R A C T Hepatotoxicity in one of the major parameters need to be consider in drug therapy, because most of the drugs in single at low/high doses for a prolonged period or multiple ... Read More »

Analytical Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Linagliptin and Metformin in Bulk and Combined Tablet Dosage Form

G. Varun Kumar*, V. Pavan kumar, M. Gobinath, V. Hari Baskar, Ramesh Dhani, Y. Vijitha Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A new simple accurate and suitable reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Linagliptin in ... Read More »

Microwave Assisted Synthesis and Antimicrobial activities of 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro-2H-pyrrolo[2,3-c,5,4-c] di pyrazole

Ravindra S. Dhivare1, S. S. Rajput*2 1Department of Chemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2Department of Chemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T The novel pyrazole derivatives were synthesized by reacting substituted bis-chalcones with 4-hydroxy-3-methoxy benzaldehyde to get 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro -2H-pyrrolo [2,3-c,5,4-c] dipyrazole using solvent-free microwave method. All these derivatives were screened ... Read More »

Development and Validation of RP-HPLC Method for the Estimation of Olmesartan Medoxomil and Cilnidipine in Tablet Dossage Form

Devalam Madhu*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, N. Vamsi Krishna Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Olmesartan medoxomil and Cilnidipine in Tablet dosage form. Chromatogram was run ... Read More »

Evaluation of levels of minerals and trace elements of Cocoa (Theobroma cacao) in Côte d’Ivoire.

Dion-Laine Massiata1, Trebissou Jonhson Noel D2*, Lohoues Essis Esmel C 1, Sess E Daniel1 1Biochemistry Laboratory, Faculty of Medical Sciences, University of Félix Houphouët-Boigny,  BP 582 Abidjan 22- Côte d’Ivoire. 2Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University. PO Box, 582, Abidjan 22- Côte d’Ivoire. A B S T R A C T Evaluate the levels of minerals and ... Read More »

Antidepressant Activity of Different Extracts of Nelumbo Nucifera Leaves in Laboratory Animals

Krishna Prasad D*1,2, Sriharsha SN2, Madhusudan Rao Y1, V.  Naveena1 1*Vaagdevi Institute of Pharmaceutical Sciences, Bollikunta, Warangal, Telangana, India. 2Pacific College of Pharmacy, Pacific University, Udaipur, Rajasthan, India. A B S T R A C T In the present study, the anti-depressant activity of Nelumbo nucifera Gaertn. leaves (Nymphaeceae) was studied in acute model forced swimming test (FST)  and tail ... Read More »

Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles

B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »

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