Thursday , 25 July 2024

Category Archives: Pharmaceutical Sciences and research inventions

Simple Validated UV method for Lamivudine in bulk and It’s Tablets Dosage form

Asma Khanam S, Ishaq B, Hindustan Abdul Ahad*, Anusha G, Ananda Lakshmi K, Roja G Balaji College of Pharmacy, Rudrampeta bypass, Anantapur, Andhra Pradesh, India A B S T R A C T Lamivudine is prescribed to HIV patients. The present research work is to develop and validate Lamivudine by UV spectrometric method. Simple, accurate, precise and cost efficient spectrophotometric ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Gemigliptin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Y. Krishna Reddy*, Kedhareshwari, Y. Harikha, V. Harikrishna, Muzahid, K. Gopi Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Metformin and Gemigliptin by using RP-HPLC. The Phosphate buffer was pH 3.0 and the mobile phase was optimized with consists of Methanol: Phosphate buffer ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ezetamibe acid and Simvastatin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Y. Krishna Reddy*, B. Ratna Kumari, M. Sampath, B. Naresh, CH. Kavya, CH. Ramadevi Bomma Institute of Pharmacy, Khammam, Telangana, India  A B S T R A C T The chromatographic conditions were successfully developed for the separation of Ezitamibe and Simvastatin by using Agilent C18 5µm (4.6*250mm) column, the flow rate was 1ml/min, mobile phase ratio was Methanol: ACN  ... Read More »

A New RP-HPLC Method Development and Validation for the Amlodipine and Perindopril in Bulk and Tablet Dosage Form

Y. Krishna Reddy*, A. Harikrishna, B. Tharun, B. Kishore, B. Saidhulu, B. Rajitha Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Amlodipine and Perindopril  by using Kromosil C 18  (250×4.6mm, 5µ) Column, The flow rate was 1ml/min, mobile phase ratio ortho phosphoric acid ... Read More »

Study of Effect of Various-Natural Polymers in the Formulation Development of Mucoadhesive Buccal Tablets of Labetalol HCl

Y. Krishna Reddy*, G. Ganagaraju, G. Sravanthi, K. Srinivas Rao, K. Manisha, K. Mounika Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T Labetalol was formulated as buccal tablets to improve its bioavailability by avoiding first pass metabolism. HPMC K4M, HPMC K15M and HPMC K100M were selected as polymers and various formulations were prepared ... Read More »

Formulation and In-Vitro Evaluation of Effervescent Floating Tablets of Voriconazole

Y. Krishna Reddy*, T. Lavanya, T. Pulliah, T. Nagendra, T. Soundarya, Praveen kumar Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The aim of the present study was to develop effervescent floating tablets of Voriconazole to maintain constant therapeutic levels of the drug for over 12 hrs. Various grades of polymethacrylate polymers and ... Read More »

Formulation and In vitro evaluation of colon targeted mesalazine tablet for the treatment of chronic pancreatitis

Y. Krishna Reddy*, S. Krishnaveni, S. Kishore Reddy, SK. Reshma, SK. Shameem, SK. Rafiya, S. Uma Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T In the present research work sustained release matrix formulation of Mesalazine targeted to colon by using various polymers developed. To achieve pH-independent drug release of mesalazine, pH modifying agents ... Read More »

Development and Evaluation of fast dissolving tablets of Fenofibrate by enhancing dissolution rate and bioavailability

Y. Krishna Reddy*, M. Vanaja, N. Akhila, N. Mamatha, M. Sruthi, P. Srilekha Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T In the present work, an attempt has been made to develop fast disintegrating tablets of Fenofibrate. In the present work Sodium starch glycolate, Cross povidone and Cross carmellose sodium were employed as ... Read More »

Formulation Evaluation of Flunarizine Oro dispersible tablets

Y. Krishna Reddy*, S. Rakesh, S. Roja, S. Mounika, S. Bhargavi, Sd. Umma Salma Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The present dissertation work is an attempt to select the best possible diluent- disintegrant combination to formulate rapidly disintegrating tablets of Flunarizine, which disintegrates in matter of seconds in the oral ... Read More »

Analytical Method Development and Validation for the Estimation of Ceritinib by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Krishna Reddy*, K. Pranaya, K. Babu, MA. Tanjeema, N. Ravi kumar, Udayasri Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Ceritinib by using Kromosil C18 4.5×150 mm 5.0 µm, flow rate was 0.8ml/min, and mobile phase ratio was 65:35% v/v methanol: water, detection ... Read More »

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