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Category Archives: Pharmaceutical Sciences and research inventions

Identification of structurally unique molecules, phytochemical and immunological activity of medicinal plants

Ajam C. Shaikh, Amit Gupta and Sushama R Chaphalkar* Vidya Pratishthan’s School of Biotechnology (VSBT, Research Centre affiliated to Savitribai Phule Pune University), Baramati, Maharashtra, India A B S T R A C T In the present study, our group analyzed major chemical constituents that are present in fresh aqueous leaves extracts and analyzed through HPTLC (high performance thin layer ... Read More »

Preparation and Evaluation of Mucoadhesive Opthalmic Niosomes of Acyclovir Using Chitosan and Carbopol

Dr. Raghvendra1*, Pragya Sharma1, Nidhi Dhama2 1Assistant Professor, Department of Pharmaceutics, Aligarh College of Pharmacy, Aligarh, U.P., India, 202001 2Assistant Professor, Department  of Pharmaceutics, Translam Institute of Pharmaceutical Education and Research, Meerut, U.P. India, 250001 A B S T R A C T Niosomes have been reported as a possible approach to deliver the drug to ophthalmic cavity. Niosomes were ... Read More »

Formulation and In-Vitro Evaluation of Doxorubicin Microspheres for the Treatment of Lymphoblastic Leukemia

Kondru Lalitha*, Beedha Saraswathi Mother Teresa Pharmacy College, Kothuru, Sathupally- 507303, Khammam, Telangana, India A B S T R A C T In the present work, bioadhesive microspheres of Doxorubicin using Sodium alginate along with Carbopol 934, Carbopol 971, HPMC  K4M as copolymers were formulated to deliver Doxorubicin via oral route. The results of this investigation indicate that ionic cross linking technique Ionotropic gelation ... Read More »

Determination of Total Phenolic and Tannins in different Varities of tea by Colorimetry

G. Somasekhar*, M. Madhavi, S. Jaheeda Bee, G. Sudeer, S. Salraju, M. Shakirbasha Department of Pharmmaceutical Chemistry, Safa College of Pharmacy, B. Tandrapadu, Kurnool A B S T R A C T Camelia Sinensis Linn., commonly known as ‘Tea, is widely distributed in most tropical countries and have been used  for varied purposes; to treat different kinds of pathologies, particularly ... Read More »

Solubility and Dissolution Rate Enhancement of Olmesartan Medoxomil by Hydrotropy and Development of Oral Disintegrating Tablets

Angilicam Avinash*, Avula Sushma, Koneti Lalasa, Siddabathina Prasanth Kumar, Thumati Gowthami, Dr. M. Sreenivasulu   Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh, India-524003. A B S T R A C T This research work was designed to enrich the solubility of olmesartan medoxomil by Hydrotropy technique and to develop the oral disintegrating tablets. Olmesartan medoxomil is an anti-hypertensive drug which ... Read More »

Preparation and Characterization of Novel Co-Crystal Forms of Domperidone

P. Mounika1*, G. Divya1, S. Vijaya Raj1, A. Gowramma2 1Department of Pharmaceutical Analysis, Sree Vidyanikethan College of Pharmacy, A.Rangampet, Tirupati, A.P, India. 2Department of pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati, Andhra Pradesh, India. A B S T R A C T Domperidone is a widely used antiemetic, poorly water soluble drug, erratically absorbed in stomach and possess several ... Read More »

A Review Based on Nasal Drug Delivery System

Navneet Kumar Verma*, J.N. Mishra, D.K. Vishwakarma, Gulzar Alam Department of Pharmacy, Kailash Institute of Pharmacy and Management, GIDA, Gorakhpur, U.P. India-273209 A B S T R A C T Nasal drug delivery system (NDDS) has been used as a substitute route for the systemic accessibility of drugs restricted to intravenous administration. This is due to the porous endothelial membrane, ... Read More »

A Brief Study on Syzygium Cumini Linn- A Review

A Brief Study on Syzygium Cumini Linn- A Review Navneet Kumar Verma*, J.N. Mishra, Gulzar Alam, A.P. Singh Department of Pharmacy, Kailash Institute of Pharmacy and Management, GIDA, Gorakhpur, U.P. India-273209 A B S T R A C T Syzygium cumini, commonly known as black plum or “jamun” is an important medicinal plant in various traditional systems of medicine. It ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Acetaminophene and oxycodone by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

V. Hari Baskar*, V. Pushpalatha, M. Gobinath, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, Andhra Pradesh, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid Chromatographic Method for simultaneous estimation of Acetaminophine and Oxycodone in pure drug form. ... Read More »

HPTLC, LC-MS Aided Qualitative, Quantitative Phytochemical Screening and Immunosuppressive Activity of Medicinal Plants

Ajam C. Shaikh, Amit Gupta and Sushama R Chaphalkar* Vidya Pratishthan’s School of Biotechnology (VSBT, Research Centre affiliated to Savitribai Phule Pune University), Baramati, Maharashtra, India A B S T R A C T This study analyzed major chemical constituents present in fresh leaves extracts of Strychnus nuxvomica, Emblica officinalis, Ficus racemosa and Syzygium cumini was collected, powdered and then ... Read More »

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