Sunday , 28 July 2024

Category Archives: Pharmaceutical Sciences and research inventions

Determination of Febuxostat by Complexation with Mercury (Hg II) Ions Using Spectrophotometry

G. Somasekhar*, P. Mamatha, S. Nirosha rani, N. Raja Kumar, S. Ismail Zabiullah, M. Mahaboob Basha Department of Pharmaceutical Chemistry, Safa College of pharmacy, Dupadu, Kurnool, A.P. India A B S T R A C T A simple, sensitive and accurate Colorimetric method was described for the determination of Febuxostat (FBX) an antigout drug. The method is based on yellow coloured ... Read More »

Synthesis and Evaluation of Anti-Inflammatory, Analgesic, Ulcerogenicity, and Nitric Oxide Releasing studies of Novel Pyrimidine Analogs as non-Ulcerogenic Derivatives

Nileema S. Modhave1*, Trupti S Chitre2, Vidya P Pawar2, 1Pad. Dr. D. Y. Patil Institute of Pharmacy, Sec.29, Nigadi Pradhikarn, Akurdi, Pune-411044 2A.I.S.S.M.S. College of pharmacy, Near RTO, Kennedy Road, Pune-411001, Maharashtra, India A B S T R A C T Most non-steroidal anti-inflammatory drugs (NSAIDs) suffer from the deadlier gastrointestinal (GI) toxicities. In the present research work, the main ... Read More »

Preparation and Evaluation of Cosmetic Cream Containing Fruits

Lavanya M1, Naresh Gorantla1, Srinivasa Reddy Bhavanam2 1Balaji College of Pharmacy, Anantapur, Andhra Pradesh, India. 2CDSCO, SR Nagar, Hyderabad, Telangana, India. A B S T R A C T The present study was aimed to prepare and evaluate the cosmetic cream containing fruit juices of five different fruits. Different types of formulations of oil in water (o/w) type creams namely ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Albuterol & Ipratropium Bromide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Chatla Sunil Kumar*, G. Devikasubramaniyan Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Albuterol and Ipratropium bromide in bulk and Pharmaceutical dosage form. The separation was effected on an Inertsil ODS (250×4.6mm) 5µm Column by using a mixture ... Read More »

Formulation and Evaluation of Lornoxicam Loaded Solid Lipid Nanoparticles

Yeduru Krishna Raddy*1, Dr. Shailesh Sharma2 1Pharmaceutical Sciences, NIMS Institute of Phrmacy, NIMS University, Shobhanagar, Jaipur, Rajasthan 2Associate Professor, NIMS Institute of Phrmacy, NIMS University, Shobhanagar, Jaipur, Rajasthan A B S T R A C T Inflammation is a common phenomenon involving interrelationships of humoral and cellular reactions through a number of inflammatory mediators. Lornoxicam, a new non-steroidal anti-inflammatory drug ... Read More »

Formulation and Comarative Evaluation of Amlodipine Besylate Fast Disintegrating Tabltes Prepared by Dry and Wet Granulation Techniques

B.V. Ramana1*, T.E.G.K. Murthy2 1Research Scholar, Rayalaseema University, Kurnool, Andhra Pradesh, India 2Bapatla College of Pharmacy, Bapalta, Guntur Dist, A.P, India A B S T R A C T An Attempt was made to improve the disintegration capacity and Dissolution efficiency of the prepared formulations with the use of mixture of superdisintegrants. Amlodipine Besylate prepared alone with super disintegrates has ... Read More »

Formulation and Evaluation of Topical Proniosomal Gel of an Anti Fungal Drug-Itraconazole

Srividhya Vardhani CH*, Nirosha M Department of Pharmaceutics, Oil Technological and Pharmaceutical Research Institute, JNTUA Ananthapuramu, India A B S T R A C T Proniosomal gels are the liquid crystalline compact Niosomal hybrids that can be converted into niosomes immediately upon hydration or used as such in the topical/ transdermal applications. Itraconazole is an Anti fungal drug which on ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ezetamibe and Simvastatin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Y. Krishna Reddy1, Dr. P.M Patel2 1Associate Professor, Bomma Institute of Pharmacy, Khammam, Telangana, India 2Principal, Kalol Institute of Pharmacy, kalol, Gujarat, India A B S T R A C T A new method was established for simultaneous estimation of Ezetamibe and Simvastatin by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Ezetamibe and Simvastatin by ... Read More »

Formulation and Evaluation of Desvenlafoxacine Succinate Hydrogel

M. Siddeswara*, M. Purushothaman, M. Pradeep Kumar, M. Santhosh Raja, S. Yasmin, R. Swathi  Department of Pharmaceutics, Vasavi Institute of Pharmaceutical Sciences, Kadapa, A.P, India A B S T R A C T Corn starch is abundantly available in nature with the help of it we can prepare controlled release dosage form.  Starch hydrogel is the current area of research ... Read More »

Preparation, In-vitro Characterization of Transdermal Proniosome Gel Containing Nifedipine

P. Anitha*, M. Purushothaman, P. Gowthami, D. Bhargavi, M. Krishnaveni, M. Rajesh, O. Sudheer Kumar  Department of Pharmaceutics, Vasavi Institute of Pharmaceutical Sciences, Kadapa, A.P, India A B S T R A C T As an alternative to oral route, transdermal route of drug delivery was developed because of its limitations. This delivery has limitations in permeation of most drugs. One ... Read More »

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