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Seelam Manasa*, Y. Krishna Reddy Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana A B S T R A C T The present investigation of the development of floating tablets are used in the treatment of high blood pressure in the lungs (pulmonary arterial hypertension). The Bosentan floating tablets were prepared by direct compression method. The evaluation of Precompression Blend Flow ... Read More »
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Category Archives: Pharmaceutical Sciences and research inventions
A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms
Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »
Antioxidant and Antimicrobial Activity of Grape Skin
Ms. Sneha V & Dr. V. Judia Harriet Sumathy Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai – 600 006. A B S T R A C T Grape (Vitis vinifera) skins and seeds are considered to be rich sources of poly-phenolic compounds.Using the sap of grapevines, European folk healers sought to cure skin and eye diseases. Other ... Read More »
Pharmacovigilance Methods: A Review
Musali Muni kumari*, Saritha Chandra, Dr. P. Venkatesh Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukur (M), SPSR Nellore-524348. A B S T R A C T Pharmacovigilance is “defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, principally long term and short term adverse effects of medicines. It is an important and ... Read More »
Medicinal Chemistry of Tyrosine Kinase Inhibitor Drug: A Review
Amol S Dighe*1, Sagar D. Magar1, Nachiket S. Dighe2 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India. A B S T R A C T Tyrosine kinases are a part of many cell functions, including cell signaling, growth, and division. These enzymes may be too active or found at high levels in some types of ... Read More »
Antimicrobial Activity of Crude Extract and Carotenoid Pigments from Flowers
Ms. Ancilla Senoretta B. & Dr. V. Judia Harriet Sumathy Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai – 600 006. A B S T R A C T All human pharmaceuticals now in use are originally derived from natural sources. According to studies conducted by the World Health Organization (WHO), about 80% of the world’s population relies ... Read More »
Review on Nanosuspensions
Siddeswara*, M. Pradeep Kumar, M. Santhosh Raja, S. Yasmin, Vijay Kumar Vasavi Institute of Pharmaceutical Sciences, Kadapa, Andhra Pradesh, India-516247 A B S T R A C T Solubility is the crucial factor for drug effectiveness, independence of the route of administration. Large proportions of newly discovered drugs are water insoluble, and therefore poorly bioavailable contributing to deserted development effort. These ... Read More »
Review on Stem Cell Therapy
S.P. Likitha Rao*1, Dr. Anil Middah1, Dr. Neeraj Tandan2 1OPJS University, Rajasthan, India 2SARC (Scientific and Applied Research Centre), Meerut, India A B S T R A C T Stem cells have the ability to differentiate into specific cell types. The two defining characteristics of a stem cell are perpetual self-renewal and the ability to differentiate into a specialized adult ... Read More »
Stability indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Olmesertan Medoxomil and Chlorthalidone in Pharmaceutical Formulation
Haribaskar*, T. Revathi, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, Andhra Pradesh, India A B S T R A C T A new method was established for simultaneous estimation of Olmesertan medoxomol and Chlothalidone by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Olmesertan medoxomil and Chlorthalidone by using C18, 250 ... Read More »
Simple, Convergent Synthesis and Characterization of benzimidazole derivatives (pyrazole linked pyridine): Micro-wave, Sonication and Conventional methods
Dr. Bommera Sammaiah, M. Venkanna, Dr. R. Madhusudhan Raju* Department of Chemistry, University College of Science, Osmania University, Hyderabad, India. A B S T R A C T The preparation of skeleton is an important in the novel drug development. Herein, the skeleton is developed based on anti-ulcerative drugs. A convergent synthesis, approached to simplify the synthesis and succeeded to ... Read More »
