Sunday , 28 July 2024

Category Archives: Pharmaceutical Sciences and research inventions

Formulation and In-vitro Evaluation of Dofetilide Fast Dissoloving Tablets

Narayana Rao Alla*, Usha Tatikonda, Dr. Satya Narayana Tanuku Mother Theresa Pharmacy College, Sathupally, Khammam, Telangana, India ABSTRACT The present study was aimed to formulate fast dissolving tablets of Dofetilide. In the present work Sodium starch glycollate, Cross povidone and Cross carmellose sodium were employed as super disintegrating agents to enhance the solubility and dissolution rate of selected drug molecule. ... Read More »

A Study of Drugs Prescribing Pattern in Upper Respiratory Tract Infections in Tertiary Care Hospital

Saritha Chandra*, Mudda Rajasekhar, Tatiparthi Dana Abhishek, Pasala Sai Mounika, Jugunta Anusha Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukuru (M), Nellore, Andhra Pradesh, India. ABSTRACT Scope of prescribing pattern emphasize study on every pattern of therapy impose in treatment goal of Upper respiratory tract infections. Especially use and choice of drugs as mono therapy, dual therapy, triple therapy. The ... Read More »

A Review on Diabetic Nephropathy

D. Saikoteswar sarma, Dr. M. Alagusundaram, N. Viharika, SK. Asha Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukuru (M), Nellore, Andhra Pradesh, India. ABSTRACT Diabetic Nephropathy is defined as a persistent albuminuria and more commonly diagnosed by a urinary excretion of more than 300 mg/24 hour. It develops in around one third of patients with diabetes, with the Asia, Pacific ... Read More »

Method Development and Validation for Simultaneous Estimation of Velpatasvir and Sofosbuvir by Using RP-HPLC in Bulk and Pharmaceutical Dosage Form

Durbhakula Pradhathri*, P. Sirisha, AVSS. Gupta, A. Mohan Goud, P. Nagaraju, M. Shyamala, J. V. C. Sharma, G. Srimounika, B. Anusha Reddy, V. Revathi Department of Pharmaceutical Analysis & Quality Assurance, Joginpally BR Pharmacy College, Moinabad, Rangareddy, Hyderabad, Telangana. ABSTRACT A New method was established for simultaneous estimation of Velpatasvir And Sofosbuvir by RP-HPLC method.   Chromatographic separations were carried using YMC (4.6 ... Read More »

Formulation and Evaluation of Gastro Retentive Effervescent Floating Tablets of Diltiazem

Katta Sridhar*, Kongi Kavya Sudha, Ballavolu Sandeep, Chirumanu Ramadevi Swathi College of Pharmacy, Venkatachalem, Nellore, Andhra Pradesh, India ABSTRACT In the present research work controlled release floating matrix formulations of Diltiazem by using various concentrations of polymers sodium bi carbonate were developed. After the preformulation studies the formulation blends were subjected to evaluation tests of various precompression and post compression ... Read More »

Formulation and In-vitro Evaluation of Daclatasvir Dihydrochloride Oral Dispersible Tablets

Dr. Satyanaraya Tanuku, Sravani Annapureddy, AdapaSatish Kumar, Dr. N. Dora Babu, B. Saraswathi Mother Theresa Pharmacy College, Kothuru Village, Sathupally -507303, Khammam, Telangana, India Abstract In the present work, an attempt has been made to develop fast disintegrating tablets of Daclatasvir dihydrochloride. In the present work Solutab, Polyplasdone XL and Explotab were employed as super disintegrating agents to enhance the ... Read More »

Formulation and In-vivo Evaluation of Atovaquone Solid Dispersions

Dr. M.V. Ramana1, Radhika Padarthy2 1Principal, Gurram Balanarasaiah Institute of Pharmacy, Edulabad, Ghatkesar, Ranga Reddy–501 301. 2Research Scholar, Department of Pharmaceutics, JNTU Hyderabad, Telangana A B S T R A C T In the present study Atovaquone solid dispersions were prepred in order to improve the bioavailability and solubility of the drug by using PVP, PEG 5000, Poloxamer 188 as ... Read More »

Analytical Method Development and Validation for Rabeprazole and Itopride in API and Combine Pharmaceutical Dosage Forms by RP-HPLC

Sanju Srinivas1, M. Suman2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana ABSTRACT A new method was established for simultaneous estimation of Rabeprazole and Itoprideby RP- HPLC method. The chromatographic conditions were successfully developed for the separation of Rabeprazole and Itopride by using Agilent C18 column (4.6×150mm) 5µ , ... Read More »

Study of Validation Procedure for Ezetimibe and Simvastatin in its Pure and Pharmaceutical Dosage Form using HPLC and its Behavior in FT-IR

Sanju Srinivas1, A. Jayalaxmi2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana ABSTRACT A new method was established for simultaneous estimation of Ezetimibe  and Simvastatin by RP-HPLC method. The chromatographic conditions were success fully developed for the separation of Ezetimibe   and Simvastatin by using Thermosil C18 column (4.0×125mm) 5µ ... Read More »

Evalaution of Antihyperlipidemic Activity of Boerhavia Diffusa Plant Leaves Extarct in Mice

Gampa Vijaya Kumar1, S. Raju2, G. Sridhar3 1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Assistant Professor, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. Abstract Major complications of hyperlipidemia are atherosclerotic heart disease, heart attack and ... Read More »

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