Friday , 26 July 2024

Category Archives: Pharmaceutical Sciences and research inventions

RP-HPLC Method Development and Validation for Simultaneous Estimation of Paracetmol and Flupirtine Maleate in Tablet Doses Form

K. Puspavathamma, V. Hari Baskar*, B. Prathap, Ramesh Dhani, P. Rameeza Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India Abstract A new method was established for simultaneous estimation of Paracetamol and Flupirtine maleate by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Paracetamol and Flupirtine maleate by using Symmetry C18 ... Read More »

Formulation and In-vitro Evaluation of Olmesartan Medoxomil Solid Dispersions

Radhika Padarthy*1, Dr. M. Venkata Ramana2 1Research Scholar, Department of Pharmaceutics, JNTU Hyderabad, Telangana 2Principal, Gurram Balanarasaiah Institute of Pharmacy, Edulabad, Ghatkesar, Ranga Reddy – 501 301. A B S T R A C T The main objective of the current research was to improve the dissolution rate and solubility of an antihypertensive drug Olmesartan Medoxomil(OM) using cyclodextrin inclusion complexation ... Read More »

Formulation and Evaluation of Apremilast Topical Gel

Adapa Satish Kumar, Marvathu Subash Chandra Bose, Dr. Tanuku Satyanarayana Mother Theresa Pharmacy College, Kothuru Village, Sathupally -507303, Khammam, Telangana, India  A B S T R A C T In the present work an attempt was being made to formulate and evaluate topical gel containing anti inflammatory drug Apremilast. Carbopol 971, Sodium CMC and carbopol 934 were selected as polymers. ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril Maleate and Metoprolol by RP-HPLC Method

Pakir Pranaya* Guru Nanak Institute of Pharmacy, Ibrahimpatnam, Rangareddy, Telangana, India.  A B S T R A C T The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and economical for simultaneous estimation of Metoprolol and Enalapril Maleate in tablet dosage form. From literature review and solubility analysis initial chromatographic conditions Mobile phase ortho phosphoric acid ... Read More »

RP HPLC Method Development and Validation of Bicaultamide and Simvastatin in Bulk and Pharmaceutical Dosage Forms

C. Srinavya*1, P. Sowjanya2, Dr. Gampa Vijaya Kumar3 1,2KGR Institute of Technology and Management,   Rampally,   Kesara,   Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Bicalutamide and Simvastatin by RP-HPLC method.  The chromatographic ... Read More »

Formulation and Evaluation of Simvastatin Nanosponges by Emulsion Solvent Diffusion Method

S. Bhuvaneswaria*, S. Sanjeeva kumara, P. Preethia, B. Josepha, V. Viswanath, B. Narasimha Rao, S. Rahath fathima, B. Syed Salman a*Department of Pharmaceutics, P. Rami reddy memorial college of pharmacy, Kadapa, Andhra Pradesh, India-516003 A B S T R A C T Targeted drug delivery system is based on a method that delivers a certain amount of a therapeutic agent ... Read More »

Formulation and Evaluation of 5-Fluorouracil Floating Beads

Nagadeepa Papireddygari*, Venkata Ramana Bachu, Venkata Badarinath Atluri Dr. K. V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India – 518218 A B S T R A C T The novel design of an oral controlled drug delivery system should be primarily aimed   at achieving more predictable and increased bioavailability of drugs. These considerations have led to the development ... Read More »

Pharmacognostical and Preliminary Phytochemical Evaluation of Orophea Uniflora

M. Purushothaman*1, J. Karthi 2 1Scient Institute of Pharmacy, Ibrahinpatnam, Hyderabad-501506, India. 2Sun Rise University, Alwar, Rajasthan – 301030, India. A B S T R A C T The whole plant material of Orophea Uniflora was collected and powedered. The powdered material was subjected to successive soxhlet extraction with petroleum ether, chloroform, ethanol and finally macerated with water so as ... Read More »

A Review-Cure the Cancer with Amagdalin / Laetrile

Kongi Kavyasudha*, Batamsetty Lakshmi Suja, Suram Sneha, Ballavolu Sandeep, Katta Sridhar Swathi College of Pharmacy, Venkatachalem, Nellore, Andhra Pradesh, India ABSTRACT Many cancer patients treated with conventional therapies also try ‘alternative’ cancer treatments. Laetrile is one such ‘alternative’ that is claimed to be effective by many alternative therapists. Krebs had found the complete control for all cancers with the laetrile. ... Read More »

Analytical Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms by RP-HPLC

G. Madhavi1, S. Sravani1, G. Nikithareddy1, V. Mounika1, B. Divya1, M. Chaithanya*1, Bijjiga Sravanthi2 1Bojjam Narasimhulu Pharmacy College, Sayeedabad, Hyderabad, Telangana-500059. 2KP Labs, Kothapet, Hyderabad-500035 A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid Chromatographic Method for simultaneous estimation of Valsartan and Sacubitril in ... Read More »

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