Kommu Pradeep*, Athuluri Venu1 *Scholar, Department of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur 1DCRM Pharmacy College, Inkollu A B S T R A C T The main objective of transdermal drug delivery system is to deliver drugs into systemic circulation into the skin through skin at predetermined rate with minimal inter and intra patient variation. Currently transdermal delivery is one of ... Read More »
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Category Archives: Pharmaceutical Sciences and research inventions
Formulation and Evaluation of Keterolac solid lipid nanoparticles
Kommu Pradeep*, Athuluri Venu1 *Scholar, Department of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur 1DCRM Pharmacy College, Inkollu. A B S T R A C T Transdermal patches of Keterolac solid lipid nanoparticles were prepared and evaluated. Stable nanoparticles of SLNs were prepared using high-shear homogenization followed by ultrasonication technique. 32 factorial designs were used in the process of optimization. This ... Read More »
Preparation and evaluation of polyherbal formulation for its hepatoprotective activity against ethanol mediated paracetamol induced intoxication rat model
A. Prathyusha*, Konda Ravi Kumar1 *Department of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur, Andhra Pradesh. 1Hindu College of Pharmacy, Guntur A B S T R A C T Objective: The present work was executed to evaluate the hepatoprotective potency of a polyherbal preparation. The objective of this study is to induce experimental hepatotoxicity using ethanol mediated paracetamol in normal Albino ... Read More »
RP-HPLC Method Development and Validation for the Estimation of Olanzapine in bulk drug and tablet dosage form
Gobalakrishnan P*1, Munisekhar V, Hemanth Kumar V 1Department of Pharmaceutical Analysis, Vagdevi College of Pharmacy and Research Centre, Nellore, Andhra Pradesh, India. A B S T R A C T The methods developed for the determination of Olanzapine are simple, selective and offer the advantages of high sensitivity without the need for extraction.. A new method was developed for Stability ... Read More »
Development and Validation of a Stability Indicating Assay Method for the Determination of Sultiam in Tablet Dosage Form by RP-HPLC
A. Srikanth*, S. Mohammed Yusuf2 *Assistant Professor, Department of Pharmaceutical Analysis, Vasavi Institute of Pharmaceutical Sciences, Kadapa. 2Assistant Professor, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Ethiopia. A B S T R A C T A new method was developed for Stability Indicating Assay Method for the Determination of Sultiam in Tablet Dosage by using RP-HPLC method. ... Read More »
Investigation for Anti-Ulcer Properties of Aqueous Extracts Prepared from the Leaves of Ocimum Sanctum in Rats
G. Ramya1, Dr. Y. Sridhar2, Dr. Gampa Vijay Kumar 3, Murali Sollu4 1,2,3,4KGR Institute of Technology and Management, Rampally (V), Kesara (M), Medchal-501301, Telangana, India. A B S T R A C T Stress causes an ischemic condition in the gastric mucosa by activation of parasympathetic and sympathetic nervous system it indicates vasoconstriction. It causes free radical generation. Aspirin which ... Read More »
Formulation and In-Vitro Evaluation of Ganciclovir Liposome
Kethavath Kumar1, Dr. V. Anjaneyulu2, Dr. G. Vijay Kumar3 1,2,3KGR Institute of Technology And Management, Rampally, Keesara, Medchal-Malkajgiri, Telangana, India. A B S T R A C T Ganciclovir, is an antiviral medication used to treat cytomegalovirus (CMV) infections. In the present work an attempt was being made to formulate and evaluate ganciclovir liposomes. Phosphatidylcholine, Cholesterol, Methanol and Chloroform were ... Read More »
Formulation and In-vitro Evaluation of Cetylpyridinium Chloride Buccal Patch
N. Karnakar1, H. Ramana2, S. Swathi3, K.Pramod4, R. Vasanthi5 1,2,3,4Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Telangana. 5School of Pharmacy, GITAM Deemed to be University, Hyderabad. A B S T R A C T In present study buccal drug delivery of Cetylpyridinium was developed to overcome the first pass metabolism and to reduce frequency of dosing compared to oral route. ... Read More »
Design Development and In-vitro Characterization of Guaiphenesin Sustained Release Tablets
H. Ramana1, N. Karnakar2, K. Nagarjuna3, R. Vasanthi4, Tamrat Balcha5 1,2,3Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Telangana. 4School of Pharmacy, GITAM Deemed to be University, Hyderabad. 5Department of Pharmacy, College of Health Sciences and Medicine, Wolaita Sodo, University, Ethiopia. A B S T R A C T The aim of the present study was to develop sustained release formulation ... Read More »
Identification, Evaluation and Synthesis of Several Process, Degradation impurities of SGLT2 inhibitor Remogliflozin Etabonate
Chander Reddy Kesireddy*a, Dr. Satyavir Singh* Research Scholar*a Department of Chemistry, Shri Venkateswara University, Venkateshwara Nagar, Rajabpur Gajraula, Amroha, UP-244236 Research Supervisor * Department of Chemistry, Shri Venkateswara University, Venkateshwara Nagar, Rajabpur Gajraula, Amroha, UP-244236 Abstract A simple convenient and effective process for Remogliflozin etabonate disclosed, in addition to that several process related and degradation impurities were identified and evaluated ... Read More »