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Sravan Kumar. P *, Sabareesh Reddy. M, Umasankar.K, Alagu Sundaram. M, P. Jaya Chandra Reddy Krishna Teja Pharmacy College, Chadalawada Nagar, Tirupathi-517506, Andhra Pradesh, India Abstract In the present study, the tablets were prepared by melt granulation method, using the polymer, hydroxy propyl methyl cellulose (HPMC K4M),Carbopol with different amounts and other excipients and sodium bicarbonate and citric acid as gas ... Read More »
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Category Archives: Pharmaceutical Sciences and research inventions
Synthesis, Characterization and Evaluation of Antimicrobial profile of 4-Thiazolidinone derivatives
Asish Bhaumik*1, M. Upender Kumar1, M. Sucharitha1, Dr. P. Panneerselvam2, Sunil Kumar Sing2 1Dept. of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India 2Dept. of Pharmaceutical Chemistry, C.L. Baid Metha College of Pharmacy, Jyothinagar, Thoraipakkam, Chennai-600097, India. Abstract The objective of the present work was the synthesis of N-[2-(4-substituted phenyl)-4-oxo-1,3-thiazolidine-3-yl]-2-(naphthalene-2-yloxy)acetamide and evaluation of in-vitro antimicrobial activity. Based on this a ... Read More »
Formulation and Evaluation of Floating Matrix Tablets of Telmisartan
1U. Sambamoorthy*, 1D. Yashwant kumar, 2G. Venkata Ramana, 3K. Suresh, 4J. Sunil 1SARC – (Scientific and Applied Research Center) Hyderabad 2Balaji institute of Pharmaceutical sciences, Narsampet, Warangal, Telangana. 3Pratishta Institute of Pharmaceutical Sciences, Durajpally Suryapet, Telangana. 4Geetanjali college of Pharmacy, keesara, Hyderabad, Telangana. Abstract Floating drug delivery systems (FDDS) have a bulk density less than gastric fluids and so remain ... Read More »
In-Vitro Characterization of Amylodipine Besylate Floating Microspheres
Panga Latha1*, K. Umasankar1, M. Alagusundaram1, M. Srikanth Reddy1, G. Devi Nagajyothi1, M. Mallika1, Jagadesh kumar yadav.K2 1Department of pharmaceutics, Krishna Teja College of Pharmacy, Tirupathi, Andhra Pradesh, India 2Department of pharmaceutics, Sree Vidyanikethan College of Pharmacy, Tirupathi, Andhra Pradesh, India Abstract Amylodipine besylate is a anti-hypertensive drug (or) blood pressure reducer, having the 64% bio-availability .in the present study focus ... Read More »
Isatine: A Versatile Heterocyclic Molecule
Shailee Tiwari* Department of Pharmaceutical Chemistry, YB Chavan College of pharmacy, Aurangabad, India Abstract Heterocyclic compounds are present in many of our medicines used today. This article gives detailed information on isatine which is one of the versatile heterocyclic molecule. It is a synthetically versatile molecule, a precursor for a large number of pharmacologically active compounds. Isatin and its derivatives ... Read More »
Solid Dispersion-A Strategy for Improving the Solubility of Lipophilic Drugs
Krishna Moorthy S.B,*1 Sandeep. J2, Rajalakshmi.R1, Rubiya SK1, Saddam hussain. SK1 1Department of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupathi, Andhra Pradesh, India. 517102. 2Department of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupathi, Andhra Pradesh, India. 517503. Abstract Improving oral bioavailability of drugs those given as solid dosage forms remains a challenge for the formulation scientists due to solubility ... Read More »
Efficient Computational Analysis of 4-(butan-2-ylideneamino)-N’-ethylidenebenzohydrazide Derivatives for Design of Anti microbial agents
Manocha Nimita, Bahrani Pankaj, Jain Neha* Department of Pharmaceutical Chemistry, Swami Vivekanand College of Pharmacy, Indore M.P, India-452001 Abstract QSAR studies were performed on selected series of 4-(butan-2-ylideneamino)- N’-ethylidenebenzohydrazide derivatives. The best quantitative structure activity relationship models were further validated by LOO method of cross-validation. The study of best model shows that the steric property like Radius (Rad) contributed negatively ... Read More »
Evaluation of antidiabetic activity of methanolic leaves extract of Lagerstroemia microcarpa in streptozotocin induced diabetic rats
Revitha. L, C.D. Shaji Selvin* Sree krishna College of Pharmacy and Research Centre, Parassala, kerala, India Abstract In the present study, the effect of alcoholic leaves extract of Lagerstroemia microcarpaon blood glucose,plasma insulin, and carbohydrate metabolic enzymes were studied in experimental diabetes. Diabetesmellitus was induced by a single intraperitoneal injection of STZ (60 mg/kg bw). ... Read More »
A Noval Approach of Fast Dissolving Films: A Review
B. Ramesh*, K. Saravanakumar, K. Jagadish kumar, SK. Saddham hussain Department of pharmaceutics, Sree Vidyanikethan College of Pharmacy, Tirupathi, Andhra Pradesh, India Abstract The main objective of proposed work is to enhance the bioavailability of selective drug by rapid dissolving films techniques. Rapidly dissolving films (RDF) are the most advanced form of oral solid dosage form due to more flexibility ... Read More »
Whipple’s Disease: A Mini Review
Kattula Rao Vinay Rajan1*, Pasam Sathish Sreenivas2, Pilla Sree Surya Durga Devi1, Penugonda Vineela1, Haritha Allu1, Prasad Reddy M1, Ravisankar Pasam3 1Doctor of Pharmacy, GIET School of Pharmacy, Rajahmundry, A.P, India 2Department of Medicine, Rangaraya Medical College, Kakinada, A.P, India 3Konaseema Institute of Medical Sciences and Research Foundation, Amalapuram, A.P, India Abstract Whipple’s disease is a rare, multi-systemic chronic infectious ... Read More »
