Sunday , 28 July 2024

Category Archives: Pharmaceutical Sciences and research inventions

Design and Evaluation of Entecavir Sustained Release Microspheres

B. Venkateswara Reddy*, G. Shankar, K. Navaneetha Department of Industrial Pharmacy, St.Paul’s College of Pharmacy, Hayathnagar, Hyderabad, R.R.Dist-501510, India A B S T R A C T The present research work is aimed to design oral twice a daily sustained release microspheres of Entecavir, used for the treating or preventing Hepatitis B which can release the drug for 10 to ... Read More »

Method Development and Validtion of Melphalan Injection by RP-HPLC Method

Gummi Vishwanth*, P. Sunith, Naga Jyothi. C Pharmaceutical Analysis and Quality Control,   JNTUH, Hyderabad, India A B S T R A C T A simple, rapid, sensitive, accurate and precise RP-HPLC method has been developed and validated for the estimation of melphalan in injection dosage form. The mobile phase used was a combination of Methanol, Acetonitrile, TEA in the ratio ... Read More »

Anti-Depressant Activity of Alstonia Venenata R.Br Stem Bark Extracts in In-vivo Methods

C. Pradeep Kumar*, T. Sravanthi, Dr. Vijaya Kuchana, CH. Maheswara Reddy Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana, India A B S T R A C T The ethanolic extract of Alstonia venenata R.Br stem bark was subjected for phytochemical investigation and LD50 studies. It was found that ethanolic extract contained reducing sugars, proteins. Aminoacids, flavonoids, phenolic compounds and ... Read More »

Method Development and Validation studies of Pregabalin Drug by RP-HPLC Method

Eswara Rao Bammidi*1, Vaikuntarao Lakinani1, Subrahmanyam Lanka1, Mallikarjun Rao Duvvada2 1Departmernt of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, A.P., India 2Departmernt of Environmental Sciences, GITAM Institute of Science, GITAM University A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of related substances in Pregabalin in bulk and ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Ambroxol HCL and Levocetrizine in Its Bulk and Dosage Form by RP-HPLC

R. Vivek*, Dr. T. Rama Mohan Reddy, Dr. V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Hyderabad, Rangareddy, India A B S T R A C T A simple Reverse phase liquid chromatographic method has been developed and subsequently validated for simultaneous determination of Levocetirizine and Ambroxol HCl in combination. The separation ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Albendazole and Ivermectin Tablet of Dosage Form by RP-HPLC

B. Saidulu*, G. Usha Sree, Dr. V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Hyderabad, Rangareddy, India A B S T R A C T A reverse phased liquid chromatography (LC) method was developed and validated for simultaneous estimation of albendazole and ivermectin in tablet dosage form. The isocratic LC analysis was ... Read More »

A Novel RP-UPLC Method for the Simultaneous Estimation of Domperidone and Rabeprazole in Pharmaceutical Dosage Form

K. Spandana*1, N. Venkatesh1, K. Suresh2, U. Sambamoorthy1 1SARC – (Scientific and Applied Research Center) Hyderabad, India 2Pratishta Institute of Pharmaceutical Sciences, Durajpally, Suryapet, Hyderabad, India A B S T R A C T A simple, accurate, rapid, precise and novel Reverse phase Ultra Pressure liquid chromatographic method has been developed and validated for simultaneous determination of Domperidone and Rabeprazole ... Read More »

Thalassemia: An Inherited Autosomal Recessive Disorder of Human Blood

Subha Ganguly* Faculty of Fishery Sciences, West Bengal Univerity of Animal and Fishery Sciences, 5, Budherhat Road P.O. Panchasayar, Chakgaria, Kolkata-700 094, WB, India A B S T R A C T Thalassemia is a form of inherited autosomal recessive blood disorders characterized by abnormal formation of hemoglobin. Thalassemia is caused by variant or missing genes that affect how the ... Read More »

Inductively coupled plasma emission spectroscopy an overview

*M. Hari Krishna, G. Nagasowjanya, V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Rangareddy, Hyderabad, India A B S T R A C T Inductively coupled plasma/optical emission spectrometry (ICP/OES) is a powerful tool for the determination of metals in a variety of different sample matrices. With this technique, liquid samples are ... Read More »

Nanorobots–A sensor based control applied to Nanomedicine

*Sonalika patro, Ch. Praveen Kumar Ratnam Institute of Pharmacy, Pidathapolur, Nellore – 524346, Andhra Pradesh, India A B S T R A C T The ability to manipulate matter at the nano scale is one core application for which nanorobots could be the technological solution. Nanorobots would constitute any passive or active structure capable of actuation, sensing, signalling, intelligence and ... Read More »

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