K. Jithendra Kumar*, M.V. Jhansipriya, Narapusetty Naidu Department of Pharmaceutics, Bellamkonda Institute of Technology & Sciences, Kambhalapadu, Podili ABSTRACT Carbamazepine (CBZ) is used for epilepsy but has also been reported to have effect in treating bipolar disorder. The absorption is 75% because of first pass hepatic metabolism, Its half life is 10-20 hrs and it is a BCS – class ... Read More »
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Category Archives: Pharmaceutical Sciences and research inventions
Pharmacological and Toxicological Studies of Cyclosporine for Anti-Rheumatoid Activity
Sana Farheen1, *Priyanka.K2, Rangam Chariitha3 1,3Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Palamuru University, Mahabubnagar, Telangana 2Department of Pharmaceutical Analysis, Smt. Sarojini Ramulamma College of Pharmacy, Palamuru University, Mahabubnagar, Telangana ABSTRACT Cyclosporine A (CsA) is an immunosuppressant that has been widely used as a gold standard treatment for various conditions. Beyond its primary role in immunosuppression, CsA has ... Read More »
Evaluation of antidiabetic activity of folklore medicinal extract in streptozotocin induced diabetic rats-10.30904/j.jpbr.2024.4713
Saba Firdous1, Rangam Chariitha*, M.Bhaskar3 Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Palamuru University, Mahabubnagar, Telangana 3Department of Pharmaceutical Analysis, Smt. Sarojini Ramulamma College of Pharmacy, Palamuru University, Mahabubnagar, Telangana A B S T R A C T The present study was designed to emphasize the anti-hyperglycaemic and antioxidant potential of the aqueous extract of the leaf of ... Read More »
Formulation and Evaluation of Sustained Release Mucoadhesive Bilayer Tablets of Nifedipine and Hydralazine HCl Using Statistical Optimization Technique
N. Janaki*, C. Mokshavathi, Dr. U. Mohan Kumar, Dr. S. Shameem, Dr. A. Sai Poojitha, S. Venkata Subbaiah Department of Pharmaceutics, Nirmala College of Pharmacy, Kadapa Dist., Andhra Pradesh A B S T R A C T This study aimed to enhance the bioavailability and sustain the release of antihypertensive drugs nifedipine and hydralazine HCl, both of which suffer from ... Read More »
Fabrication and Evaluation of Micellar Structure of Pluronic Copolymer Nanoaggregates of Cabazitaxel
Shaik Parveen1, G. Mahaboob Basha*2 1M. Pharm Student, Department of Pharmaceutics, Prabhath Institute of Pharmacy, Parnapally (Vil.), Bandiatmakur (MD), Nandyal Dist., Andhra Pradesh 2Associate Professor, Department of Pharmaceutics, Prabhath Institute of Pharmacy, Parnapally (Vil.), Bandiatmakur (MD), Nandyal Dist., Andhra Pradesh A B S T R A C T Conventional therapy available for lung cancer has untended consequences and oral dosage ... Read More »
Evaluation of Clinical Outcomes in Covid 19 Patients Treated with Casirivimab-Imdevimab Antibody Cocktail–A Prospective Observational Study
Sreemantula Divya*, Tummala Vaishnavi1, Tagore Jaya Sree1, Tharigoppula Harini1, P. Naveen Kumar1, Saritha Jyostna Tangeda1 , Venu Talla1 Sarojini Naidu Vanita Pharmacy Maha Vidyalaya, Tarnaka, Hyderabad, India. A B S T R A C T Cocktail is a composition of 2 antibodies Casirivimab and Imdevimab that is mostly given in the omicron variant of covid-19. The objectives of the study ... Read More »
Formulation and Evaluation of Microparticulate Controlled Release Solid Dosage Form of Nateglinide
C. Venkata Sai Manoj Kumar*, A. Deepthi, Dr. U. Mohan Kumar, P. Sravanthi, G. Balachandra, T. Mounika Department of Pharmaceutics, Nirmala College of Pharmacy, Kadapa Dist., Andhra Pradesh A B S T R A C T Nateglinide is a widely used oral antihyperglycemic agent for managing non-insulin-dependent diabetes mellitus (NIDDM), belonging to the meglitinide class of short-acting insulin secretagogues. Due ... Read More »
In vitro α amylase, α glucosidase inhibitory and antioxidant activities of Benincasa hispida (thunb.) Cogn. Fruit and seed extracts
E. Vijay Kumar*, Chappidi Pranaya Veena1, Chilakala Sreelakshmi2, Dhanikela Sneha3, Gownivaripalli Shafiya4, Kattubadi Hameeda5 *Associate Professor, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P, India 1,2,3,4,5Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P, India A B S T R A C T Diabetes mellitus, characterized by impaired carbohydrate utilization due to insulin deficiency, is a prevalent metabolic disorder worldwide. Existing modern pharmacotherapy’s ... Read More »
In-vitro Anti-arthritic Activity of Leaves of Momordica Charantia Linn.,
P. Gobala Krishnan*1, Vonteru Muni Sekhar2, V. Hemanth Kumar3, G. Sadik4 1Professor and Principal, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346. 2,3Associate Professor, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346. 4Assistant Professor, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346 A B S ... Read More »
In-Vitro Evaluation of Moringa oleifera Leaves Powder for Antidiabetic Activity
Cheryl S Raj* 11th Standard, BASE PU College, 62, 2nd Main Rd, 4th Phase, West of Chord Road, Shivanagar, Rajajinagar, Bengaluru, Karnataka-560010 A B S T R A C T Moringa oleifera Lam., also known as the ‘drumstick tree,’ is recognized as a vibrant and affordable source of phytochemicals, having potential applications inmedicines, functional food preparations, water purification, and biodiesel ... Read More »