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About author : Ramesh Dhani JNTUA-OTRI, Anantapur, India Dept. of Pharmaceutical Chemistry E-mail: dhanipharmachem@gmail.com ABSTRACT: Oxazole is the parent compound for a vast class of heterocyclic aromatic organic compounds. These are azoles with oxygen and nitrogen separated by one carbon. Oxazoles are aromatic compounds but less so than the thiazoles. Oxazole is a weak base; its conjugate acid has a ... Read More »

About author : Ramesh Dhani Dept. of  Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS ... Read More »

About author : Ramesh Dhani Dept. of  Pharmaceutical Chemistry JNTUA-OTRI, Anantapur,India ABSTRACT: Quinazoline is a bicyclic compound earlier known as benzo-1, 3-diazine. The name quinazolinone (German: Chinazolin) was proposed for its compound by wedding, on observing that this was isomeric with the then compound crinoline and quinaoxaline. The numbering of the quinazoline ring system which is currently used was suggested ... Read More »

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Oxazole is a heterocyclic organic compound that has a five-member ring molecular structure, containing oxygen, nitrogen as heteroatoms at its 1, 3-positions.  Benzoxazoles are derivatives of oxazoles. Benzoxazoles is a planar molecule with conjugated p electrons sextets in the cyclic systems. The lone pair of ... Read More »

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Quinazolinones and several of their derivatives have been found to be of greater interest in view of their varied biological and pharmacological properties. The ... Read More »

About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5, 6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12. Diversity ... Read More »

About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Herbal Medicine can be broadly classified into various basic systems: Traditional Chinese Herbalism, which is part of Traditional Oriental Medicine, Ayurvedic Herbalism, which is derived from Western Herbalism, which originally came from Greece and Rome to Europe and then spread to North and South America. Indian ... Read More »

About author Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Many important biochemical compounds and drugs of natural origin contain heterocyclic ring structures. Among these e.g. Carbohydrates, essential amino acids, vitamins, alkaloids, glycosides etc. the presence of heterocyclic structures in such diverse types of compounds is strongly indicative of the diverse types of the pharmacological activity. ... Read More »

 About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: The process of establishing a new drug is exceedingly complexioned involves the talents of people from a variety of disciplines including Pharmaceutical chemistry, biochemistry, physiology, pharmacology, pharmaceutics and medicine. Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the ... Read More »

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT:  Heterocyclic drug having wide spectrum of activity, Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, antihistaminic, anticancer and so on. All the synthesized quinazolinone derivatives were confirmed preliminarily by M.P and TLC ... Read More »