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A New RP-HPLC method developed and validated for the estimation of Tolterodine

Gobalakrishnan P*1, Munisekhar V, Hemanth Kumar V 1Department of Pharmaceutical Analysis, Vagdevi College of Pharmacy & Research Centre, Nellore, Andhra Pradesh, India. A B S T R A C T A rapid and sensitive RP-HPLC Method with UV detection (283nm) for routine analysis of Tolterodine in Bulk and in Pharmaceutical formulation was developed. Chromatography was performed with mobile phase containing ... Read More »

Analytical Method Development and Validation of Hydrochlorothiazide and Eposartan in API and its Dosage form by RP-HPLC

R. Narsimha Rao1, N. Karnakar2 J. Sushma3, P. Amani4 1,2,3,4Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Telangana. A B S T R A C T On the basis of experimental results, the proposed method is suitable for the quantitative determination of Hydrochlorothiazide and Eposartan in pharmaceutical dosage form. The method provides great sensitivity, adequate linearity and repeatability. The estimation of ... Read More »

Regulatory Approval Procedures in USA

J. Praveen Kumar1, Rajendran Sai Divya2, Dr. M. Kishore Babu3, Dr. P.V. Murali Krishna4 1Associate Professor, Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh. 2Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh. 3Principal, Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh. 4Associate professor, MNR College of Pharmacy, Sangareddy, Hyderabad, Telangana. A B S T R A C T The Food and Drug Administration ... Read More »

Preparation and Evaluation of Solid dispersions of Febuxostat

Radhika P*, Venkata Ramana M1 *Moonray College of Pharmacy, Hyderabad, Telangana. 1Azad College of Pharmacy, Hyderabad, Telangana A B S T R A C T Among the various methods of enhancement of dissolution rate and oral bioavailability, cyclodextrin complexation and solid dispersion technologies were found to be very successful with Febuxostat. As such their oral bioavailability and efficacy are severely ... Read More »

Nesting and Breeding Success of Red-Whiskered Bulbul, Pycnonotus jocosus (Linnaeus, 1758) in Pratapgarh, Uttar Pradesh, India

Arun Kumar Tripathi Shree Krishna Educational Institute, Sitapur, Uttar Pradesh, India A B S T R A C T The observation of nesting and breeding successofthe red-whiskered bulbul, Pycnonotus jocosus (Linnaeus, 1758) wasmade locallyin Pratapgarh, Uttar Pradesh, India.A pair of red-whiskered bulbul built a cup-shaped nest on potted holy basil (Ocimum sanctum) plant at a height of 96 cm from ... Read More »

Pharmacological Evaluation of Antidepressant Activity of Ethanolic Extract of Magnolia Officinalis in Mice

Srujana, Kakirala Anila, M.G.Anujaah, Akkem Gayatri, Ramdas Mallika, Kondapu Reddy Neethu Reddy Bojjam Narasimhulu Pharmacy College for women, Vinaynagar, Hyderabad-500059, Telangana. A B S T R A C T Depression is the most common of the affective disorders (disorders of mood rather than disturbances of thought or cognition); it may range from a very mild condition, bordering on normality, to severe ... Read More »

Bioanalytical Method for Quantification of Torsemide in Human Urine Using LC-MS/MS

S. Satheshkumar*1, V. Muruganantham2 1Ph.D. Scholar, Department of Pharmaceutics, College of Pharmacy, Vinayaka Mission’s College of Pharmacy, Salem- 636008, Tamilnadu, India 2Professor, Department of Pharmaceutics, College of Pharmacy, Vinayaka Mission’s College of Pharmacy, Salem- 636008, Tamilnadu, India. A B S T R A C T Anaccurate and simple method was developed using high performance liquid chromatography with electron spray ionization ... Read More »

Marketing Authorization of Generic Drugs and Challenges

A. Lavanya1, M. Usha Harika2, Dr. M.Kishore Babu3, Dr. P.V. Murali Krishna4 1Assistant Professor, Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh. 2Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh. 3Principal, Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh. 4Associate professor, MNR College of Pharmacy College, Sangareddy, Hyderabad, Telangana. A B S T R A C T An Abbreviated New Drug Application (ANDA) ... Read More »

Epidemology, Etiology and Management of UTI in Patients with Type-2 Diabetes Mellitus

Ch. Rajyalakshmi Swetha1, J. Mallika2, K. Sravani3, C. Pavithra4, V.S. Premchand5 1Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2,3,4,5Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A B S T R A C T In this present study, the bacteria as etiological agents of urinary tract ... Read More »

Analytical Method Development and Validation of Mupirocin and Bromelain in API and Its Dosage Form by RP-HPLC

N. Karnakar1, B.Manisha2, R. Narsimha Rao3, P. Amani4 1,2,3,4Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Telangana. W. J. Pharm. Biotech., 2021, 8(1): 01-04 A B S T R A C T A new method was established for simultaneous estimation of Mupirocin and Bromelain by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Mupirocin and Bromelain by ... Read More »

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