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Cellular mechanisms involved in Helicobacter pylori induced infection and its eradication strategies by potential root extracts of Plumbago zeylanica L

Author Details G. Renuga*1 and A. Kennath2 1Department of Biotechnology, Ultra College of Pharmacy, Madurai, Tamil Nadu, India. 2Department of Oral Pathology, Ultra Best Dental science college, Madurai, TN,   India. Abstract The research was designed to investigate H. pylori infection induced in mouse can be used as a model to design a drug for the treatment of peptic ulcer. A ... Read More »

Formulation and In-vitro Evaluation of fast Disintegrating Tablets of Zaltoprofen

Author Details Sanjay K. Sharma*, Md. Nawaz Alam, Manish Jaimini, Arindam Chatterjee, Shailender Mohan  Department of Pharmaceutics, Jaipur College of Pharmacy, ISI-15, RIICO, Sitapura Institutional Area, Sitapura, Jaipur (Raj.), India. Abstract An attempt was made to formulate the fast disintegrating dosages form of Zaltoprofen using various superdisintegrants viz. sodium starch glycolate, croscarmellose sodium and crospovidone. FD tablets containing 80 mg of Zaltoprofen ... Read More »

Management of Sub Clinical Mastitis in Crossbred Cows with Herbal Topical Gel “Mastilep”

Author Details P. Hase1, S. Digraskar1, K. Ravikanth2, A Thakur2*, S Maini2 1Department of Veterinary Medicine, College of Veterinary and Animal Sciences, MAFSU, Parbhani, Maharashtra, India 2R&D, Ayurvet Limited, Baddi, HP, India Abstract The prevention of bovine mastitis is the most important component of a mastitis control programme. A clinical trial was conducted to evaluate therapeutic efficacy of Mastilep gel (supplied ... Read More »

Method Development and Validation of Telmisartan in Bulk and Pharmaceutical Dosage Forms by UV Spectrophotometric Method

Author Details N. Samba Siva Naik*, G. Sai Phani, SD. Fathima Zahera, N. Sai Priyanka and CH. Ravi Tej Department of Pharmaceutical Analysis and Q.A, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta Group of Institutions, Narasaraopet, Guntur (Dt.), Andhra Pradesh, India Abstract This research article describes the analytical method suitable for validation of Telmisartan by UV–spectro-photometric method. The method was utilized UV-Spectroscopy ... Read More »

Ketoconazole Solubility Enhancement: Different Techniques and its Comparison

Author Details Ravi Prakash*, Shashi Shekhar Tripathi, Pravin Gupta, Rahul Dev, Anaagat Sir Madanlal Institute of Pharmacy Aalampur Hauz, Etawah-206001, U.P., India Abstract Four techniques namely melt sonocrystallization, solid dispersion, hydrotrophy and inclusion complex with cyclodextrin were used for the solubility enhancement. The order of the techniques for the solubility enhancement was found hydrotrophy>inclusion complex>solid dispersion>sonocrystallization method. Enhancement in the ... Read More »

Ranitidine hydrochloride multiparticulate floating drug delivery system: Formulation and evaluation

Author Details Anaagat*, Shashi Shekhar Tripathi, Pravin Gupta, Rahul Dev, Ravi Prakash Sir Madanlal Institute of Pharmacy AalampurHauz, Etawah-206001, U.P., India Abstract Gastroretentive Drug Delivery Systems (GFDDS) are retained in the stomach for a longer time and assist in improving the oral controlled delivery of drugs that have an absorption window in the particular region of the GI tract as ... Read More »

Development and validation of High Performance Thin Layer Chromatography for estimation of Cefpodoxime Proxetil and Dicloxacillin sodium in combined tablet dosage form

Author Details 1Patel Advaita B*, 2Madhabhai M Patel, 3Bhanubhai N Suhagiya 1Department of pharmaceutical chemistry, Kalol institute of Pharmacy, Kalol, India 2Director and   Principal of Shankersinh Vaghela Bapu Institute of Pharmacy 3Dean at Faculty of Pharmacy, Dharmsinh Desai University, Nadiad Abstract High performance thin layer chromatography for estimation of Cefpodoxime Proxetil and Dicloxacillin Sodium in their combine dosage form was ... Read More »

Stability indicating High Performance Thin Layer Chromatographic determination of Raloxifene Hydrochloride

Author Details Rajasekaran A*, Preethi N, Arivukkarasu R  Department of Pharmaceutical Analysis, KMCH College of Pharmacy, Coimbatore, India Abstract A simple, sensitive, selective, precise and stability indicating high-performance thin-layer chromatographic method was developed and validated for the determination of raloxifene hydrochloride as per the ICH guidelines. Precoated aluminium plates with silica gel 60F254 as the stationary phase and methanol: water: ... Read More »

Validated RP-HPLC Method for Simultaneous Estimation of Lisinopril and Hydrochlorothiazide in Combined Dosage forms

Author Details P. Nagaraju*, G. Indira Priyadarshini, SA. Bilal Ahmed and V. Siddhartha Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur–522 002, Andhra Pradesh, India. Abstract A rapid and sensitive reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for simultaneous estimation of Lisinopril and Hydrochlorothiazide. Chromatographic separation was achieved on reverse phase Agilent LC 1100 ... Read More »

Spectrophotometric Determination of Trace Lead in Biological Samples by using 2,4-di Methoxy benzaldehyde isonicotinoyl Hydrazone (DMBIH)

Author Details Ramakrishna Reddy. K*, Devanna. N, Chandrasekhar. K.B Department of Chemistry, JNTUA, College of Engineering, Anantapur, A.P, India. Abstract A rapid, simple, sensitive and selective spectrophotometric method has been developed for the determination of Lead (II) using newly synthesized Chromogenic reagent 2, 4-Dimethoxy benzaldehyde isonicotinoyl hydrazone (DMBIH). Lead (II) forms bright yellow coloured water soluble complex with DMBIH in ... Read More »

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