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Synthesis of s-Triazine substituted analogues of 1,5-benzodiazepines of medicinal interest

Vandana Singh*, Aditi Anand and D. Kishore  Department of Chemistry, Banasthali University, Banasthali-304022 (Rajasthan), India Abstract Synthesis of a series of 1,5-benzodiazepines substituted on its 3 and 4 positions with 2’-(amino /ethylamino/ piperidino-(4,6-biscyclopropylamino)) -1,3,5-triazines 12,10,7 and 14 respectively, from 2-methyl-1,5-benzodiazepin-4-one (4) has been described. Keywords: 1,5-Benzodiazepine, 2,4,6-trichloro-1,3,5-triazine.   Read More »

A Study on Phytoremediation of Heavy Metals from Paper Mill Effluent Soil Using Croton Sparsiflorus

B.Ashokkumar1*, S.Jothiramalingam2, S.K.Thiyagarajan3, T.Hidhayathullakhan4 and R. Nalini5  1Research scholar, Khadir Mohideen College, Adirampattinam – 614701, Thanjavur (Dt), Tamilnadu, India. 2 & 3 P.G and Research Department of Chemistry, A. V. V. M. Sri Pushpam College (Autonomous), Poondi-613 503, Thanjavur (Dt), Tamilnadu, India. 4Department of chemistry, Khadir Mohideen College, Adirampattinam – 614 701, Thanjavur (Dt), Tamilnadu, India. 5Department of Chemistry, Periyar Maniammai University, ... Read More »

Nanoparticles Based Therapeutics and Drug Delivery–A Review

Krishna moorthy S.B*, Rajalakshmi R, Rupangada V, Sravanthi R.R, Ramya sudha EM.  Department of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupathi, Andhra Pradesh, India-517102 Abstract Nanocarriers are colloidal particulate systems which size ranges from 10-1000 nm. They have been successfully utilized in the diagnosis, treatment and monitoring of various diseases. Targeted delivery of drug molecules is one of ... Read More »

Anti-inflammatory activity of aqueous extract of Mimusops elengi in human whole blood and peripheral blood mononuclear cells

Amit Gupta*, Pallavi R Khamkar and Sushama R Chaphalkar  Department of Immunology, Vidya Pratishthan’s, School of Biotechnology (VSBT), Baramati, District Pune, Maharashtra, India Abstract The aim of the present study is to present a simple, fast and reliable method of anti-inflammatory activity of medicinal plants especially Mimusops elengi in human whole blood and peripheral blood mononuclear cells using flow cytometry. To ... Read More »

Estimation of chlorophyll content of some medicinal plants of genus Terminalia of Marathwada region in Maharashtra

Kadam V.B*, Salve S. B, Sonawane M.D, Ahire P.P  P.G. Department of Botany & Research Centre, K.T.H.M. College, Nasik–422002 Abstract The seasonal variation (summer, Monsoon and winter) of chlorophyll a, chlorophyll b and carotenoid have been investigated in leaves of Terminalia cuneata Roth. Terminalia bellirica Roxb, Terminalia chebula Retz. and Terminalia catappa Linn. are important medicinal plants of family Combretaceae ... Read More »

Preparation and Evaluation of Physical properties Ibuprofen matrix tablet using Tamarand indica as colon targeted drug

Prashant Patil1*, S.N.Sriharsha1, Yashwant Kumar.D1, K.S.S.N. Neelima2 1Pacific College of Pharmacy, Pacific University (PAHER), Udaipur, India 2SARC- (Scientific and Applied Research Centre) – Hyderabad Abstract The present study was undertaken to assess the potential of Tamarind seed polysaccharide (TSP) to act as a biodegradable carrier for colon specific drug delivery. Hence an attempt was made to develop matrix tablet based ... Read More »

Formulation and Evaluation of Fluoxetine Fast Dissolving Tablets

Ajay Kumar A*, Haranath C Raghavendra Institute of Pharmaceutical Education & Research, Ananthapuramu, AP, India. Abstract The main aim of the present study was develop and evaluate the fast dissolving tablets of Fluoxetine by direct compression method. Sodium starch glycolate, Crospovidone and Croscarmellose sodium were used as super disintegrants to achieve the desired disintegration time required for the fast dissolving ... Read More »

Evaluation of Potential Effect of Terminalia Arjuna against Inflammatory Bowel Disease

Bariya Aditi Hemrajbhai1*, Patel Madhabhai Manohardas2, Anand Indermeet Singh3  1Assistant Professor, Department of Pharmacology, Kalol Institute of Pharmacy, Kalol-382721, Gujarat, India. 2Principal & Director, Shankersinh Vaghela Bapu Institute of Pharmacy, Vasan, Gandhinagar, Gujarat, India. 3Professor & Head, Department of Pharmacology, Shree Sarvajanik Pharmacy College, Mehsana, Gujarat, India. Abstract Terminalia arjuna wight & Arn. is a deciduous and evergreen tree, belongs ... Read More »

Design and Evaluation of Labetalol Bilayered Tablets

M. Ravi*, Dr. S.K. Umadevi, Dr.B. Venkateswara Reddy, K. Navaneetha Department of Pharmaceutics, St.Pauls College of Pharmacy, Turkayamjal (V), Hayathnagar (M), R.R.Dist-501510 Abstract Bilayered Tablets are used to produce repeat action or prolonged action by separating physically or chemically incompatible ingredients. The present study was carried out to exploit the feasibility of using controlled delivery bilayered tablets of labetalol as ... Read More »

A Study on Phytochemical and Antioxidant Activity of Merremia Turpethum

Syeda Jeelani Basri T*1, Dr. G.V. Subba Reddy2, Dr. K.N. Jayaveera3  1Department of Chemistry, Research Scholar JNTUA, Anantapur-515001, A.P, India. 2Department of Chemistry, Vice Principal, JNTU A College of Engineering Pulivendula, Pulivendula, A.P, India. 3Department of Chemistry, JNTUA, Anantapur-515001, A.P, India. Abstract Phytochemical analysis of Merremia turpethum plant samples revealed presence of Alkaloids, Amino acids, Carbohydrates, Glycosides, Anthraquinone, Saponin, Tannin ... Read More »

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