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Bioequivalence Comparison between two Different Formulations of Alverine Citrate 120mg Capsules: An Open Label, Balanced, Randomized-Sequence, Single-Dose, Two-Period Crossover Study in Healthy Male Volunteers

I. Sarath Chandiran*1, Raghunadha Reddy Seelam2, Seelam Sai Satyanaraya Reddy3, Ravindra Reddy S3 1Professor, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore-524346, Andhra Pradesh, India 2Department of Pharmaceutical Science, School of Pharmacy, University of Maryland, Pine Street, Baltimore, Maryland 21201, USA. 3Vardhaman College of Engineering, Hyderabad, Telangana, India. A B S T R A C T This present bioequivalence study was designed ... Read More »

Synthesis and Biological Evaluation of Novel Pyrimidine Derivatives as Potential Anticancer agents

Khalid M.H. Hilmy*a, Mohamed M.M. Solimana, Esmat B.A. Shahinb, Maha M.A. Khalifac aDepartment of Chemistry, Faculty of Science, Monufyia University, Shebin El-Kom, Egypt. bDepartment of Biochemistry, Faculty of Medicine for girls, Al-Azahar University, Naser City, Cairo, Egypt. c Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azahar University, Naser City, Cairo, Egypt A B S T R A C T A ... Read More »

Efficient Ultrasound Synthesis and Antimicrobial Studies of Novel Schiff Bases of Isoniazid

Ganesh S. Kulkarni, Priyanka L. Anandgaonker, Sidharth D. Janrao, Digambar D. Gaikwad and D. M. Janrao* 1Department of chemistry J.E.S. College Jalna-431203 2Deptment of Chemistry, Govt. College of Arts & Science, Aurangabad-431001 A B S T R A C T Hydrazones possessing an azometine -NHN=CH– proton constitute an important class of compounds for new drug development. In the present protocol ... Read More »

Biochemical Evaluation of Some Medicinal Plants of Genus Terminalia (Combretaceae) of Marathwada Region in Maharashtra

Kadam V.B*1, Salve S.B1, Deore S.V1, Patil Vikas2, Khandare K.R3 1P. G. Department of Botany & Research Centre, K. T. H. M. College, Nasik, India-422002 2Dy. Registrar, Savitribai Phule Pune University, Pune, India 3Department of Botany, Arts, Commerce and Science College, Satana, Nashik, India A B S T R A C T The seasonal variation of total ash, acid soluble ... Read More »

Method Development and Validation for Simultaneous Determination a Multiple Drug Dosage Form of Paracetamol, Phenylepherine and Caffeine by RP-HPLC

Dr. Samson Israel Deta*1, Dr. Kommana Balaram Kumar2, Hayelom G/Kirstos Mangesha3 1Asst. Prof, Adigrat University, Ethiopia 2Asst.Prof, University of Gondar, Ethiopia 3Lecturer, Adigrat University, Ethiopia A B S T R A C T This method describes a procedure to quantify the assay of Paracetamol, Phenylepherine and caffeine tablet using a mobile phase containing containing mixture of 880 mL of sodium ... Read More »

Evaluation of an Expired Non-Toxic Amlodipine Besylate Drug as Corrosion Inhibitor for Low Carbon Steel in Hydrochloric Acid Solutions

A.S. Fouda*1, M. S. Motawee2, H. S. Megahid2, H. A. Abdul Mageed1 Chemistry Department, Faculty of Science, Mansoura University, Mansoura-35516, Egypt. A B S T R A C T Inhibition of low carbon steel corrosion by Amlodipine Besylate in 1M HCl was investigated by weight loss, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS) & electrochemical frequency modulation (EFM) measurements. The inhibition ... Read More »

Synthesis and Screening of (E)-1-(4-(2(((Phenylamino) Methyl) amino) acetyl) phenyl)-4-(2-phenylhydrazono)-3-(Trichloromethyl)-1H-pyrazol-5(4H)-one

G.S.S. Anjaneya Vasavi, M. Uma Maheshwar Rao, S. Sreenivasulu*, M. Venu Gopal   Department of Chemistry, R.G.M. College of Engineering Technology (Autonomous) Nandyala A B S T R A C T Synthesis of (E)-1-(4-(2-(((phenylamino) methyl) amino) acetyl) phenyl)-4-(2phenyl hydrazono)-3-(trichloromethyl)-1H-pyrazol-5(4H)-onewasachievedbyreactionofE-2-(4-(5-o4(2phenylhydrazono)-3-(trichloromethyl acetic acid (2)) in presence of DMF, aq NaNO3, isobutyl formamide afforded corresponding compound (3) which was subjected to mannich reaction ... Read More »

Synthesis, Characterization and In-vitro evaluation of Antibacterial Profile of 1, 4-dihydropyridine derivatives

Asish Bhaumik1*, Prasenjit Das2, Shibu Das3, M. Swapna4, Mahendar Boddupally5 1,4Department of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana State, India. 2,3Department of Pharmaceutical Chemistry, Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala-799005, India 5Department of Pharmacology, Pratishta Institute of Pharmaceutical Sciences, Durajpally, Chivemla, Nalgonda-508214, Telangana State, India. A B S T R A C T The ... Read More »

Co-ordination Polymers of Schiff Bases and Their Applications: A Review

J. B. Devhade*  P. G. Department of Chemistry, Jijamata Mahavidyalaya Buldana, Maharashtra– 443001, India Abstract The condensation of primary amines with carbonyl compounds was first reported by Schiff and condensation products often referred as Schiff bases. These bases have general structure RC=NR’ where R and R’ are alkyl, cyclohexyl, aryl or heterocyclic radicals which may be differently substituted.  Schiff bases ... Read More »

A Novel Method for the Simultaneous Estimation of Imipenem and Cilastatin by Using RP-HPLC in its Bulk and Pharmaceutical Dosage Form

Satheesh thotla*, R. Vasanthi, Dr. Alagar Raja.M, K.N.V Rao, Devid Banji Departmernt of Pharmaceutical Analysis, Nalanda College of Pharmacy, Nalgonda, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Imipenem and cilastatin by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Imipenem and cilastatin by using ... Read More »

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